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ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

Brain response patterns to rewards may be influenced by gene variants affecting pain sensitivity

Patterns of brain responses to rewards are a significant predictor of pain symptoms—a link that is already present by adolescence—and may be influenced by gene variants affecting pain sensitivity, reports a study in PAIN, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer.

28 Jan 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Consumers estimate quantity decreases more accurately than increases

But whenever a brand tries to shave a few percentages off the size of their product, consumers immediately notice and complain.

28 Jan 2017

Educated African immigrant mothers rarely passed cultural views regarding sex to children, research finds

While many African immigrants make efforts to retain their culture, when it comes to sex education, acculturation can occur three times faster than average.

28 Jan 2017

Survey: Health care, unemployment, immigration, and education are top priorities for Americans

Health care, unemployment, immigration, and education top a lengthy and varied list of the American public's policy priorities for 2017, according to a new national survey conducted by The Associated Press-NORC Center for Public Affairs Research.

28 Jan 2017

New study examines link between scope-of-practice regulations and retail-based clinic growth

Just as primary care provider shortages are becoming acute, retail-based clinics in pharmacies and grocery stores are set to fill the gap in accessible patient care. Yet in some states, access to this convenient care is constrained due to restrictive scope-of-practice laws.

28 Jan 2017

Study analyses differences in voluntary pregnancy terminations between immigrant and native women

A study by the UPV/EHU-University of the Basque Country analyses the differences between immigrant women and native women in voluntary pregnancy termination rates between 2009 and 2013.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

In patients with severe obstructive sleep apnea (OSA), oral appliances that treat the condition by moving the lower jaw forward appear to improve sleep but not reduce key risk factors for developing heart and other cardiovascular disease, according to new research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

28 Jan 2017

Young and middle-aged adults may be over-treated for colon cancer, study suggests

Young and middle-aged patients with colon cancer are nearly two to eight times more likely to receive postoperative chemotherapy than older patients, yet there seems to be no added survival benefits for these patients, according to a study published today in JAMA Surgery by researchers at the Uniformed Services University of the Health Sciences.

28 Jan 2017

Study shows evidence that intestinal microorganisms can serve as link between diet and colorectal cancer

A new study provides some of the strongest evidence to date that microorganisms living in the large intestine can serve as a link between diet and certain types of colorectal cancer, the lead authors at Dana-Farber Cancer Institute and Massachusetts General Hospital report.

28 Jan 2017

Globe-trotting pollutants can last longer and travel much farther than previously predicted

A new way of looking at how pollutants ride through the atmosphere has quadrupled the estimate of global lung cancer risk from a pollutant caused by combustion, to a level that is now double the allowable limit recommended by the World Health Organization.

28 Jan 2017

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from University of Alabama at Birmingham scientists presented today in JCI Insight, a journal of the American Society for Clinical Investigation.

27 Jan 2017

Robotic telemedicine could provide reliable assessment of comatose patients

Reliable assessment of comatose patients in intensive care units is critical to the patients' care. Providers must recognize clinical status changes quickly to undertake proper interventions.

27 Jan 2017

Premature infants do not show brain response to expectations that may be key to neural development

Babies born prematurely don't use their expectations about the world to shape their brains as babies born at full term do, important evidence that this neural process is important to development.

27 Jan 2017

Penn researchers shed new light on potential causes of premature birth

Depending on the specific type, bacteria in a woman's vagina and cervix may increase the risk of premature birth or protect against it, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jan 2017

Dartmouth study examines impact of health insurance status on cancer care

Millions of Americans acquire their health insurance under the Affordable Care Act, including individuals from disadvantaged communities (as defined by a summary measure comprised of U.S. Census measures of income, education, and employment). Patients with one of the four leading causes of cancer deaths have lower rates of cancer-specific survival based on where they live, specifically based on their social determinants of health.

27 Jan 2017

Quality improvement interventions in hospitals linked to reduced Cesarean delivery rate

A new study led by clinician-researchers at Beth Israel Deaconess Medical Center has found that hospital-led interventions over a seven-year period were associated with a significant reduction in the hospital's Cesarean delivery rate.

27 Jan 2017

Education News and Research

ACMG issues new Points to Consider statement on potential clinical application of genome editing

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

Brain response patterns to rewards may be influenced by gene variants affecting pain sensitivity

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Consumers estimate quantity decreases more accurately than increases

Educated African immigrant mothers rarely passed cultural views regarding sex to children, research finds

Survey: Health care, unemployment, immigration, and education are top priorities for Americans

New study examines link between scope-of-practice regulations and retail-based clinic growth

Study analyses differences in voluntary pregnancy terminations between immigrant and native women

UAB researchers find how gut fails to prevent HIV-1 infection

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

Young and middle-aged adults may be over-treated for colon cancer, study suggests

Study shows evidence that intestinal microorganisms can serve as link between diet and colorectal cancer

Globe-trotting pollutants can last longer and travel much farther than previously predicted

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Robotic telemedicine could provide reliable assessment of comatose patients

Premature infants do not show brain response to expectations that may be key to neural development

Penn researchers shed new light on potential causes of premature birth

Dartmouth study examines impact of health insurance status on cancer care

Quality improvement interventions in hospitals linked to reduced Cesarean delivery rate

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