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High-fat diet during lactation alters RNA activity in breast milk, research suggests

New research suggests that following a high-fat diet during lactation - regardless of diet during pregnancy - alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.

21 Nov 2017

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Columbia University biologists have revealed a mechanism by which bacterial cells in crowded, oxygen-deprived environments access oxygen for energy production, ensuring survival of the cell. The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen-poor environments like biofilms and resist antibiotics.

21 Nov 2017

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Diabetes patients’ immune system can regulate insulin production

Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.

21 Nov 2017

Study finds sensors to detect biomarkers

A new study conducted at Purdue University suggests that small vibrating sensors or microelectromechanical resonators can be used to identify biological markers in small amounts of blood. This method is expected to be useful for detecting a myriad of diseases, infections, and different medical conditions in their early stages.

21 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Sensors for identifying biomarkers could help detect myriad of diseases at early stages

Purdue University researchers have found a method of identifying biological markers in small amounts of blood that they believe could be used to detect a myriad of diseases, infections and different medical conditions at early stages.

21 Nov 2017

Heart disease risk factors linked to walking difficulties in people under age of 78

Problems with balance, walking speed, and muscle strength become more common as we age, and can lead to disability. In fact, studies show that for older adults, having a slower walking speed can help predict chronic illness, hospitalization, and even death.

21 Nov 2017

UVA scientists working to find end-around method to stop triple-negative breast cancer

So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.

20 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Some scientists call it the "final frontier" of our DNA -- even though it lies at the center of every X-shaped chromosome in nearly every one of our cells.

20 Nov 2017

Over-the-counter decongestant found to be effective inhibitor of tumor stroma

CANCER researchers seeking non-toxic alternatives to harmful chemotherapy are reporting a highly significant result for a humble cold remedy.

20 Nov 2017

Mother's diet can protect nursing newborns against food allergies, research shows

Research published in the Journal of Experimental Medicine today indicates that a mother's diet can protect nursing newborns against food allergies.

20 Nov 2017

New technique holds promise to screen cancer cells for drug susceptibility

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn't working.

20 Nov 2017

Cancer drugs may offer new way to control high blood pressure

Drugs designed to halt cancer growth may offer a new way to control high blood pressure (hypertension), say Georgetown University Medical Center investigators.

20 Nov 2017

Amish people live longer due to mutation in blood clotting gene

Scientists have stumbled upon a genetic mutation that is found among the Indiana Amish community people that leads to impaired or defective blood clotting but predicts a longer life span for them. The study was published this week in Science Advances.

19 Nov 2017

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified a protein that can be targeted to suppress growth of a common type of breast cancer known as "estrogen receptor positive" (ER+), including ER+ cancers that are resistant to standard treatments.

17 Nov 2017

Researchers find way to switch tumor cells between 2D and 3D morphology

Paving the way for testing experimental drugs in more realistic environments, scientists at the National Institute of Standards and Technology have discovered how to make tiny colonies of cells grow in useful new ways inside petri dishes.

17 Nov 2017

Protein C News and Research

High-fat diet during lactation alters RNA activity in breast milk, research suggests

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

Scientists develop novel technology that uses CRISPR to map genetic mutations

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Diabetes patients’ immune system can regulate insulin production

Study finds sensors to detect biomarkers

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Sensors for identifying biomarkers could help detect myriad of diseases at early stages

Heart disease risk factors linked to walking difficulties in people under age of 78

UVA scientists working to find end-around method to stop triple-negative breast cancer

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Over-the-counter decongestant found to be effective inhibitor of tumor stroma

Mother's diet can protect nursing newborns against food allergies, research shows

New technique holds promise to screen cancer cells for drug susceptibility

Cancer drugs may offer new way to control high blood pressure

Amish people live longer due to mutation in blood clotting gene

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

Researchers find way to switch tumor cells between 2D and 3D morphology

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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