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Researchers uncover mechanism that contributes to patterns of degeneration in AD

Alzheimer's disease (AD) is known to cause memory loss and cognitive decline, but other functions of the brain can remain intact.

17 Nov 2017

Hibernating ground squirrels offer clues to fight against stroke-induced brain damage

In the fight against brain damage caused by stroke, researchers have turned to an unlikely source of inspiration: hibernating ground squirrels.

17 Nov 2017

Biologists resolve immune protein structure to provide insight into pathogen-defense strategies

Biologists have resolved the structure of a ring of proteins used by the immune system to summon support when under attack, providing new insight into potential strategies for protection from pathogens.

17 Nov 2017

Groundbreaking study identifies protein as potential factor in cancer metastasis

U of G scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues.

17 Nov 2017

Scientists identify biomarkers that predict risk of death in Ebola patients

Scientists have identified a set of biomarkers that indicate which patients infected with the Ebola virus are most at risk of dying from the disease.

17 Nov 2017

Drug used to prevent and treat malaria may also be effective for Zika virus

A new collaborative study led by researchers at Sanford Burnham Prebys Medical Discovery Institute and UC San Diego School of Medicine has found that a medication used to prevent and treat malaria may also be effective for Zika virus.

17 Nov 2017

Researchers identify possible genetic basis for coronary artery disease

The buildup of plaque in the heart's arteries is an unfortunate part of aging. But by studying the genetic makeup of people who maintain clear arteries into old age, researchers led by UNC's Jonathan Schisler, PhD, have identified a possible genetic basis for coronary artery disease (CAD), as well as potential new opportunities to prevent it.

17 Nov 2017

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

Astrocytes, the supporting cells of the brain, could play a significant role in the pathogenesis of Alzheimer's disease (AD), according to a new study from the University of Eastern Finland. This is the first time researchers discovered a direct association between astrocytes and AD. Published in Stem Cell Reports, the study investigated the brain cell function of familial AD patients by using stem cell technologies.

17 Nov 2017

Researchers map first-ever proteome of healthy human heart

A healthy heart beats about two billion times during a lifetime – thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry and the German Heart Centre at the Technical University of Munich have now determined which and how many individual proteins are present in each type of cell that occurs in the heart.

17 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

FDA approves new drug to treat bleeding in hemophilia A patients

The U.S. Food and Drug Administration today approved Hemlibra (emicizumab-kxwh) to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients with hemophilia A who have developed antibodies called Factor VIII (FVIII) inhibitors.

17 Nov 2017

Research reveals fundamental process used by immune system to recognize invading pathogens

The body's homeland security unit is more thorough than any airport checkpoint. For the first time, scientists have witnessed a mouse immune system protein frisking a snippet of an invading bacterium. The inspection is far more extensive than researchers imagined: the immune system protein, similar to those in humans, scans the bacterial protein in six different ways, ensuring correct identification.

16 Nov 2017

New pain relievers reduce opiate overdose risk

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have developed new opioid pain relievers that reduce pain on par with morphine but do not slow or stop breathing - the cause of opiate overdose.

16 Nov 2017

New discovery about immune system could pave way for better allergy treatment

Scientists have made a fundamental discovery about how our body's immune system clears harmful infections.

16 Nov 2017

Study: People less likely to have high-quality diet when healthier food is pricier than unhealthy items

When healthier food, like vegetables and dairy products, is pricier compared to unhealthy items, like salty snacks and sugary sweets, Americans are significantly less likely to have a high-quality diet, a new Drexel University study found.

16 Nov 2017

Skin patch offers hope for people with peanut allergy

People who suffer from life-threatening peanut allergies may soon be able to cure their condition by wearing a skin patch, according to the findings of a phase 2 trial.

16 Nov 2017

New research shows how a gene can fuel obesity in mice

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.

16 Nov 2017

New study identifies chemical receptors in cells to reduce drug resistance

The bacterium Pseudomonas aeruginosa is the leading cause of hospital-acquired infections. The pathogen is resistant to many antibiotics so treating those infections, particularly in patients with compromised immune systems, is difficult.

15 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017