Laboratory News and Research

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Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

When it comes to finding cures for heart disease, scientists at Icahn School of Medicine at Mount Sinai are working to their own beat. They may have developed a tissue model for the human heart that can bridge the gap between animal models and human clinical trial patients.

4 Feb 2014

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Researchers at Oregon State University have discovered a genetic function that helps one of the most important "tumor suppressor" genes to do its job and prevent cancer.

4 Feb 2014

Deficit in microglia during development can have long-lasting effects on brain wiring, behavior

In many people with autism and other neurodevelopmental disorders, different parts of the brain don't talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about.

3 Feb 2014

Researchers may solve riddle about inner workings of the brain

Stanford researchers may have solved a riddle about the inner workings of the brain, which consists of billions of neurons, organized into many different regions, with each region primarily responsible for different tasks.

3 Feb 2014

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

In recognition of his seminal work on adenoviral vectors, which accelerated the translation of gene therapy from the research laboratory to the clinic, Ronald G. Crystal, MD (Weill Cornell Medical College, Cornell University, New York City), has received a Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2014

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression.

31 Jan 2014

Study describes new tack in treatment of lung adenocarcinomas

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

31 Jan 2014

Scientists develop tissue model for human heart

When it comes to finding cures for heart disease scientists are working to their own beat. That's because they may have finally developed a tissue model for the human heart that can bridge the gap between animal models and human patients.

31 Jan 2014

Scientists discover potential cure for triple negative breast cancer

Scientists have discovered a potential cure for one of the most aggressive and least treatable forms of breast cancer called "triple negative breast cancer." In laboratory experiments involving human cancer cells, scientists used a virus similar to the one that helped eradicate smallpox to coax cancer cells to produce a protein which makes them susceptible to radioactive iodine.

31 Jan 2014

Llama-derived antibodies open door to development of new treatments for C. difficile infections

Researchers from the Alberta Glycomics Centre at the University of Calgary and the University of Alberta, in collaboration with researchers at the National Research Council of Canada in Ottawa, have revealed the first molecular views showing how highly specific antibodies derived from llamas may provide a new method for controlling deadly infections from the opportunistic bacterial pathogen Clostridium difficile (C. difficile).

31 Jan 2014

Researchers gain better understanding of HIV infection through electron microscopy

The human intestinal tract, or gut, is best known for its role in digestion. But this collection of organs also plays a prominent role in the immune system. In fact, it is one of the first parts of the body that is attacked in the early stages of an HIV infection. Knowing how the virus infects cells and accumulates in this area is critical to developing new therapies for the over 33 million people worldwide living with HIV. Researchers at the California Institute of Technology are the first to have utilized high-resolution electron microscopy to look at HIV infection within the actual tissue of an infected organism, providing perhaps the most detailed characterization yet of HIV infection in the gut.

30 Jan 2014

Third-hand smoke as deadly as first-hand smoke

Do not smoke and do not allow yourself to be exposed to smoke because second-hand smoke and third-hand smoke are just as deadly as first-hand smoke, says a scientist at the University of California, Riverside who, along with colleagues, conducted the first animal study of the effects of third-hand smoke.

30 Jan 2014

Thermo Fisher Scientific fourth quarter revenue increases 6% to $3.47 billion

Thermo Fisher Scientific Inc., the world leader in serving science, today reported its financial results for the fourth quarter and full year ended December 31, 2013.

30 Jan 2014

Researchers engineer skin cells for first time containing blood and lymphatic capillaries

Researchers at the University Children's Hospital Zurich and the University of Zurich have engineered skin cells for the very first time containing blood and lymphatic capillaries. They succeeded in isolating all the necessary types of skin cells from human skin tissue and engineering a skin graft that is similar to full-thickness skin.

30 Jan 2014

Scientists receive new awards from CIRM to advance revolutionary stem cell science in medicine

Scientists from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received new awards from the California Institute of Regenerative Medicine (CIRM), the state stem cell research agency, that will forward revolutionary stem cell science in medicine.

30 Jan 2014

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.

30 Jan 2014

EGPAF donates medical equipment to Swaziland to improve health of mothers and children

The Elizabeth Glaser Pediatric AIDS Foundation in collaboration with Project C.U.R.E (Commission on Urgent Relief and Equipment) today donated medical equipment and supplies worth more than U.S. $500,000 to the Government of the Kingdom of Swaziland's Ministry of Health to help strengthen health services provided to mothers, infants, and children in the country.

30 Jan 2014

Running is more effective than walking for breast cancer survivors

Previous studies have shown that breast cancer survivors who meet the current exercise recommendations (2.5 hours of moderate intensity physical activity per week) are at 25% lower risk for dying from breast cancer.

29 Jan 2014

Researchers discover potential treatment for viral infection that causes illnesses in children

Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.

29 Jan 2014

Laboratory News and Research

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Deficit in microglia during development can have long-lasting effects on brain wiring, behavior

Researchers may solve riddle about inner workings of the brain

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Study describes new tack in treatment of lung adenocarcinomas

Scientists develop tissue model for human heart

Scientists discover potential cure for triple negative breast cancer

Llama-derived antibodies open door to development of new treatments for C. difficile infections

Researchers gain better understanding of HIV infection through electron microscopy

Third-hand smoke as deadly as first-hand smoke

Thermo Fisher Scientific fourth quarter revenue increases 6% to $3.47 billion

Researchers engineer skin cells for first time containing blood and lymphatic capillaries

Scientists receive new awards from CIRM to advance revolutionary stem cell science in medicine

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

EGPAF donates medical equipment to Swaziland to improve health of mothers and children

Running is more effective than walking for breast cancer survivors

Researchers discover potential treatment for viral infection that causes illnesses in children

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