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NIBIB-funded researchers develop microscopic technique to improve Mohs surgery

A common surgery for non-melanoma skin cancer, known as Mohs surgery typically achieves excellent results but can be a long process, as the surgeon successively removes the area of concern until the surrounding tissue is free of cancer.

29 Jan 2014

Therapath signs contract with United Healthcare to provide neuropathology services

Therapath LLC, the leader in comprehensive diagnostic and consultative neuropathology laboratory services, has signed a national contract with United Healthcare, a division of UnitedHealth Group (NYSE: UNH), to provide the pathology analysis for these specialty services.

29 Jan 2014

Researcher receives 2014 Japan Prize in Life Sciences for extraordinary work in the field of epigenetics

C. David Allis, a pioneer in the field of epigenetics whose discovery that chemical modifications of DNA-packaging proteins play a key role in regulating the activity of individual genes, will be awarded the 2014 Japan Prize in Life Sciences. The announcement, by the Japan Prize Foundation, was made at a press conference in Tokyo this morning.

29 Jan 2014

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia.

29 Jan 2014

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which can be far from ideal for imaging cells in their in vivo state. We report on the biological application of a label-free, high contrast microscopy technique known as ptychography, in which the image producing step is transferred from the microscope lens to a high-speed phase retrieval algorithm.

From Phase Focus Limited 28 Jan 2014

Human visual system can retain plasticity even after extended blindness

Deprivation of vision during critical periods of childhood development has long been thought to result in irreversible vision loss.

28 Jan 2014

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

If the content of many a situation comedy, not to mention late-night TV advertisements, is to be believed, there's an epidemic of balding men, and an intense desire to fix their follicular deficiencies.

28 Jan 2014

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

St. Jude Children's Research Hospital scientists have discovered a promising new class of antibiotics that could aid efforts to overcome drug-resistance in tuberculosis (TB), a global killer.

28 Jan 2014

Novel brain-scanning technique maps flow of visual information in brain with unique accuracy

Every time you open your eyes, visual information flows into your brain, which interprets what you're seeing. Now, for the first time, MIT neuroscientists have noninvasively mapped this flow of information in the human brain with unique accuracy, using a novel brain-scanning technique.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

Study to evaluate connections between brain networks and religious thought

Building on previous evidence showing that religious belief involves cognitive activity that can be mapped to specific brain regions, a new study has found that causal, directional connections between these brain networks can be linked to differences in religious thought.

28 Jan 2014

New versions of old antibiotic offers strategy for overcoming drug resistance

Research led by St. Jude Children's Research Hospital scientists has produced new versions of an old antibiotic that are active against difficult-to-treat tuberculosis; offers new strategy for overcoming drug resistance

28 Jan 2014

Study shows taking vitamin D2 supplements may result in higher muscle damage in athletes

Power athletes and others looking for an edge to improve their performance should avoid taking vitamin D2.

28 Jan 2014

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Scientists have begun the first human clinical trial of EDP-788, an investigational oral antibiotic intended to treat methicillin-resistant Staphylococcus aureus (MRSA) infections.

27 Jan 2014

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

Jackson Laboratory Associate Professor Jeffrey Chuang, Ph.D., has been awarded a two-year grant totaling $519,750 from the National Human Genome Research Institute for his studies of how RNA (molecules vital to protein formation in cells) interacts with proteins to change how genes are expressed.

27 Jan 2014

ResearchDx expands operations to focus on Middle East clinical laboratory and diagnostics markets

ResearchDx, LLC of Irvine, California, USA today announced an expansion of its operations to focus on the important Middle East clinical laboratory and diagnostics markets.

27 Jan 2014

Research: Architecture of DNA maintained by protein ANP32E

A team of scientists from the National Cancer Centre Singapore (NCCS), the Institut de G-n-tique et de Biologie Moleculaire et Cellulaire (Strassbourg France), and the Institut Albert Bonniot (Grenoble, France) have made an important finding on how genes are regulated. This study will be released in the January 30th, 2014 print issue of the journal Nature.

27 Jan 2014

NIBIO signs collaboration agreement for clinical development of new mucosal TB vaccines

Japan's National Institute of Biomedical Innovation ("NIBIO"), Aeras and Create Vaccine Company, Ltd ("CREATE") announce today that they signed a collaboration agreement on December 26, 2013, on the preclinical and clinical development of new mucosal tuberculosis (TB) vaccines based on NIBIO's human parainfluenza type-2 (rhPIV2) vector technology.

27 Jan 2014

Study reveals neurons in brain can combine signals of individual elements into behavioural sequence

When you learn how to play the piano, first you have to learn notes, scales and chords and only then will you be able to play a piece of music. The same principle applies to speech and to reading, where instead of scales you have to learn the alphabet and the rules of grammar.

26 Jan 2014

New biomarker for stress in wild animals facing global climate change

Chemical analyses by neuroscientist Jerrold Meyer and colleagues at the University of Massachusetts Amherst are helping to establish hair cortisol concentration (HCC) as an important new biomarker for stress in wild animals facing global climate change.

25 Jan 2014

Laboratory News and Research

NIBIB-funded researchers develop microscopic technique to improve Mohs surgery

Therapath signs contract with United Healthcare to provide neuropathology services

Researcher receives 2014 Japan Prize in Life Sciences for extraordinary work in the field of epigenetics

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Human visual system can retain plasticity even after extended blindness

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

Novel brain-scanning technique maps flow of visual information in brain with unique accuracy

Researchers discover unusually large bacteriophage that infects anthrax bacterium

Study to evaluate connections between brain networks and religious thought

New versions of old antibiotic offers strategy for overcoming drug resistance

Study shows taking vitamin D2 supplements may result in higher muscle damage in athletes

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

ResearchDx expands operations to focus on Middle East clinical laboratory and diagnostics markets

Research: Architecture of DNA maintained by protein ANP32E

NIBIO signs collaboration agreement for clinical development of new mucosal TB vaccines

Study reveals neurons in brain can combine signals of individual elements into behavioural sequence

New biomarker for stress in wild animals facing global climate change

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