Syndrome News and Research

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Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Researchers have identified a molecular suspect in a disorder similar to multiple sclerosis (MS) that attacks the optic nerve and spinal cord, according to a report presented at the 130th annual meeting of the American Neurological Association in San Diego. The protein, called aquaporin-4, is a channel protein that allows water to move in and out of cells.

26 Sep 2005

Increasingly virulent Staph infections

In a "Brief Report" in the 22 September 2005 issue of the New England Journal of Medicine, researchers at the University of Chicago describe three cases of rapidly progressive and ultimately fatal Staphylococcus aureus infections in small children.

26 Sep 2005

Possible molecular origin of at least nine human diseases of nervous system degeneration

These neurodegenerative diseases, including Huntington's disease, share an abnormal deposit of proteins inside nerve cells. This deposition of protein results from a kind of genetic stutter within the cell's nucleus asking for multiple copies of the amino acid glutamine, a building block of protein structure.

26 Sep 2005

New nutritional challenges in HIV/AIDS care have emerged

Nutritional therapy for HIV-infected patients is shifting focus. Drug treatments designed to combat the HIV virus have improved, decreasing some nutritional problems, while bringing others to light.

26 Sep 2005

First-of-its kind atlas of the folds of the cerebral cortex

Neuroscientists at Washington University School of Medicine in St. Louis have assembled a first-of-its kind atlas of the folds of the cerebral cortex, the wrinkled surface layer of the brain credited with many of the higher cognitive functions that make us human.

26 Sep 2005

Key neural system at risk from prenatal exposure to alcohol

In a study of adult monkeys who were exposed to moderate amounts of alcohol in utero, scientists have found that prenatal exposure to alcohol - even in small doses - has pronounced effects on the development and function later in life of the brain's dopamine system, a critical component of the central nervous system that regulates many regions of the brain.

21 Sep 2005

Adult sickle cell drug hydroxyurea proves effective in young children

A drug used for the treatment of sickle cell anemia in adults has now been shown to cause significant improvements in very young children with the disorder.

20 Sep 2005

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

A large-scale study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that heavy alcohol consumption - 35 or more drinks per week -- can significantly increase men's risk of developing atrial fibrillation, a dangerous type of arrhythmia and one of the leading risk factors for stroke.

20 Sep 2005

SARS can infiltrate brain tissue

Severe acute respiratory syndrome (SARS), by its very name, indicates a disease of the respiratory tract. But SARS can also infiltrate brain tissue, causing significant central nervous system problems, according to an article in the Oct. 15 issue of Clinical Infectious Diseases, now available online.

20 Sep 2005

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

The study by Bucala and his colleagues in Dublin, Ireland, included experiments in mice that are resistant to developing asthma because they lack the gene, and an examination of a human population in Dublin chosen for their similar ethnic and geographic identity.

20 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

HOXA1 is a gene that's been looking for a disorder for a long time

Researchers at Children's Hospital Boston, who specialize in studying the genetics of rare eye-movement disorders, have found a rare genetic syndrome whose implications go far beyond the eye, raising intriguing questions about human cardiovascular and brain development.

12 Sep 2005

Unexpected link between the viruses that cause feline and human AIDS

A University of Florida researcher has discovered an unexpected link between the viruses that cause feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS virus appear to be at least as well-protected against the feline version of the disease as those immunized with the vaccine currently used by veterinarians.

10 Sep 2005

New tool to measure coma depth

Mayo Clinic neurologists have created the first new, reliable and easy-to-use clinical tool in 30 years for measuring coma depth, a proposed replacement for the Glasgow Coma Scale. The new scoring system, called the FOUR (Full Outline of UnResponsiveness) Score, will be described in the October issue of Annals of Neurology.

10 Sep 2005

Nitric oxide could one day help women in their 30s and 40s remain fertile longer

Researchers have found that an important chemical compound, nitric oxide, appears to slow or reverse the aging of eggs in mouse ovaries. The finding suggests nitric oxide could one day help women in their 30s and 40s remain fertile longer and increase their chances of having healthy babies, the scientists say.

7 Sep 2005

Researchers recommend multidisciplinary approach of low back pain

Researchers calculated the costs of management of low back pain and found that an integrated and step-wise approach within a multidisciplinary setting forms a better use of the available resources. The study is published in the September issue of Pain Practice.

7 Sep 2005

Australian Medical Association highlights dangers of alcohol during pregnancy

Australian Medical Association President, Dr Mukesh Haikerwal, said recently that the National Health and Medical Research Council (NHMRC) should revise its guidelines on alcohol consumption during pregnancy.

6 Sep 2005

Strong social gradient in the metabolic syndrome

It is well documented that individuals with higher social status have lower risk of coronary heart disease (CHD). This is generally not explained by differences in lifestyle factors such as smoking and lack of exercise.

6 Sep 2005

Amnioinfusion does not reduce the risk of meconium aspiration syndrome

An international randomized trial, funded by the Canadian Institutes of Health Research (CIHR), has revealed that amnioinfusion, the infusion of saline into the uterus, does not reduce the risk of meconium aspiration syndrome (MAS), as previously believed.

6 Sep 2005

Design of wide-spectrum inhibitors targeting coronavirus main proteases

Coronaviruses - the family of viruses that causes the common cold - gained widespread recognition when the deadly severe acute respiratory syndrome, familiarly known as SARS, killed at least 800 people in 2003.

6 Sep 2005