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Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Machine learning can pinpoint "genes of importance" that help crops to grow with less fertilizer, according to a new study published in Nature Communications. It can also predict additional traits in plants and disease outcomes in animals, illustrating its applications beyond agriculture.

25 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Pinning down Pin1: Potential COVID-19 therapy

In a recent study scientists have demonstrated that Pin1 is one of the key cellular molecules necessary for SARS-CoV-2 propagation.

22 Sep 2021

The role of nanomaterials during the COVID-19 pandemic

A new review published in Rare Metals has focused on the applications of nanomaterials to fight the ongoing COVID-19 pandemic.

22 Sep 2021

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway. These findings were published online in Cancer Research, a journal of the American Association for Cancer Research, and point to a new therapeutic opportunity for this type of ovarian cancer for which new solutions are urgently needed.

22 Sep 2021

Scientists use statistical mechanics to make sense of DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Our ability to heal and regenerate new tissue after an injury has much to do with biological sex. For instance, following menopause, the loss of sex-hormone signaling in women can lead to degenerative diseases such as osteoporosis and osteoarthritis, where bone and cartilage degrade and become more delicate and brittle because of tissue loss.

21 Sep 2021

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

Three US COVID-19 vaccines provide substantial protection against hospitalization

A new study reports that a head-to-head comparison of the efficacy of the three vaccines used in the USA indicates substantial protection against hospitalization with COVID-19 following vaccination with any of these vaccines.

21 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

In a recent study, Swiss researchers use improved techniques to understand the biological significance behind the Delta variant.

19 Sep 2021

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

18 Sep 2021

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Results from this study provided evidence for the hypothesis that sex-defining factors influence the expression of ACE2 and other SARS CoV-2 machinery.

17 Sep 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time, and the survival of such patients is often dismal.

16 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Transcription News and Research

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Exploring the polymerase of poxviruses at an atomic level

Design of mRNA vaccines to combat COVID-19

New discovery offers clues to overcoming resistance to cancer therapies

Study provides novel insights into how KLF4 influences gene expression

Pinning down Pin1: Potential COVID-19 therapy

The role of nanomaterials during the COVID-19 pandemic

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Scientists use statistical mechanics to make sense of DNA folding

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Three US COVID-19 vaccines provide substantial protection against hospitalization

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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