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Transcription factors work together to drive cancer cell proliferation

Scientists have discovered that a well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to findings published in Science Advances.

16 Mar 2022

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

Researchers determined the immune signature of the multisystem inflammatory syndrome in children among hospitalized children diagnosed with SARS‐CoV‐2 infection.

16 Mar 2022

Within-host mathematical model provides insight into dynamics of SARS-CoV-2 infection

Researchers used a within-host mathematical model to determine the dynamics of viral RNA and infectious virus titers in both aerosols and the URT.

15 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Study results in three new co-amorphous drug systems with great anti-COVID-19 potential

Researchers demonstrated that the bioavailability of matrine-type alkaloids could be prolonged by employing a co-former, resveratrol.

15 Mar 2022

One-step ELISA experiments

AMSBIO announces the launch of the QuicKey Pro™ range of ELISA kits – new easy-to-use assays that require just one step of washing, and one step of sample addition, resulting in a whole experiment taking only 90 minutes.

From AMS Biotechnology 15 Mar 2022

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

In a paper published on Small recently, a collaborated research team led by Prof. WANG Hui from High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences reported the synthesis of hollow cuprous carbon (HCONC) by one-step hydrothermal method as well as their applications in efficient chemodynamic therapy.

14 Mar 2022

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

Researchers conducted an in vitro analysis to assess the efficacy of monoclonal antibodies against the SARS-CoV-2 Omicron BA.2 and BA.1 variants.

14 Mar 2022

New insight about how blood clots are formed during wound healing

Research carried out by RCSI University of Medicine and Health Sciences has revealed new information about how blood clots are formed during wound healing.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

Researchers Dr Yansong Feng and Prof. Hong Zhang at the Van 't Hoff Institute for Molecular Sciences at the University of Amsterdam (UvA) have designed and synthesized novel multi-layered, multi-functional nanoparticles that enable a combination of radiotherapy and photodynamic therapy for deep cancer tissue.

10 Mar 2022

The Nucleic Acid Experts – Certified Twice!

BioEcho Life Sciences receives two important hallmarks for its quality management – DIN EN ISO 9001:2015 and DIN EN ISO 13485:2016.

From BioEcho Life Sciences GmbH 10 Mar 2022

IPD pooled analysis quantifies the underlying hematological response following malaria infection

A new malaria study using a very large analysis of pooled individual patient data (IPD) from more than 70,000 patients of all ages, has been published today in BMC Medicine.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

Mushroom-derived compounds have potential for use as COVID-19 therapeutic

Researchers conducted virtual screening and validation of molecules derived from mushrooms for their activity against the main protease SARS-CoV-2.

9 Mar 2022

A new view of SARS-CoV-2 genome structure

Researchers performed DMS mutational profiling with sequencing and DREEM clustering to determine the SARS-CoV-2 RNA secondary structure.

8 Mar 2022

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Researchers developed a vaccine candidate termed Ad26.COV2.S.529, encoding a stabilized Omicron-based S protein resembling ancestral SARS-CoV-2 Wuhan-Hu-1 S protein.

8 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Women with one ovary less likely to have a successful IVF outcome, study shows

Women who have had one ovary surgically removed (unilateral oophorectomy) are less likely to become pregnant after in vitro fertilization and give birth to fewer babies than women with both ovaries.

8 Mar 2022

in vitro News and Research

Transcription factors work together to drive cancer cell proliferation

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

Within-host mathematical model provides insight into dynamics of SARS-CoV-2 infection

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Study results in three new co-amorphous drug systems with great anti-COVID-19 potential

One-step ELISA experiments

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

New insight about how blood clots are formed during wound healing

Novel genetic relationships with severe SARS-CoV-2

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

The Nucleic Acid Experts – Certified Twice!

IPD pooled analysis quantifies the underlying hematological response following malaria infection

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Mushroom-derived compounds have potential for use as COVID-19 therapeutic

A new view of SARS-CoV-2 genome structure

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Current and future perspectives of mRNA technology

Women with one ovary less likely to have a successful IVF outcome, study shows

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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