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Icahn School of Medicine receives $2.7M to investigate narrow pathway targeted immune therapy

The National Institutes of Health has awarded a research team at the Icahn School of Medicine at Mount Sinai $2.7 million to study systemic treatments for patients with moderate to severe atopic dermatitis (AD), also known as eczema.

26 Nov 2013

Natural compound coumarins exhibit anti-inflammatory as well as anticoagulant activities

New methods for the laboratory-scale synthesis of coumarin-based drugs were developed in a recent study completed at the University of Eastern Finland. In his doctoral thesis, Lic. Phil. Juri Timonen also developed new analytical methods for the fast identification of natural and non-natural coumarins.

26 Nov 2013

Dysregulation of epigenetic marks may play role in chronic kidney disease, shows study

The research of physician-scientist Katalin Susztak, MD, PhD, associate professor of Medicine in the Renal Electrolyte and Hypertension Division, at the Perelman School of Medicine, University of Pennsylvania, strives to understand the molecular roots and genetic predisposition of chronic kidney disease.

26 Nov 2013

New diabetes has little impact on outcomes in elderly hypertensives

Established, but not newly diagnosed, diabetes is associated with reduced survival among elderly patients with hypertension, shows an analysis of the ANBP2 study.

25 Nov 2013

Anti-epileptic drugs, bone loss and supplements

Antiepileptic drugs are medications used to prevent and control seizure disorders. These medications are also frequently used for other diagnoses other than seizures, however this current study concentrated on patients with a seizure disorder.

25 Nov 2013

Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it recently filed an application for approval to begin a phase 2a clinical trial of its RNAi-based therapeutic candidate, ARC-520, for the potential treatment of chronic hepatitis B virus infection.

25 Nov 2013

Japanese health authorities approve Aerocrine's NIOX MINO for assessing airway inflammation

Aerocrine AB announces today that Japanese health authorities have approved the use of its FeNO-measuring device NIOX MINO as a tool for assessing patients with airway inflammation such as asthma.

25 Nov 2013

Scientists find link between airborne allergies and risk of blood cancers in women

A team of scientists looking into the interplay of the immune system and cancer have found a link between a history of airborne allergies - in particular to plants, grass and trees - with risk of blood cancers in women.

25 Nov 2013

UCSF investigator receives $89 M grant to research on anal cancer in people with HIV

A UC San Francisco investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.

25 Nov 2013

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Janssen Therapeutics, Division of Janssen Products, LP, announced today the U.S. Food and Drug Administration has approved OLYSIO (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.

23 Nov 2013

Chronic bronchitis could indicate COPD subtype

Chronic bronchitis is common among patients with chronic obstructive disease and may represent a subtype of the disease that places patients at risk for increased severity and exacerbations, say researchers.

22 Nov 2013

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

During Antibiotic Awareness Week (18-24 November) NPS MedicineWise is urging health professionals to use vaccinations as one important way to limit Australia’s use of antibiotics.

22 Nov 2013

New bill offers hope to HIV patients on transplant waiting lists

A bill scheduled to be signed into law today by President Obama reverses the longtime ban on letting HIV-infected people donate their organs for transplantation after death, a move that offers hope to thousands of HIV patients on transplant waiting lists.

22 Nov 2013

Sinai Hospital reports results from Phase 2a trial of apo A-I infusion therapy CSL112

Researchers from the Sinai Center for Thrombosis Research presented findings from a Phase 2a trial substudy that examined the antiplatelet effects of CSL112, a novel apolipoprotein A-I (apo A-I) infusion therapy, at the American Heart Association 2013 Scientific Sessions.

22 Nov 2013

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

During Antibiotic Awareness Week (18-24 November) NPS MedicineWise is urging health professionals to use vaccinations as one important way to limit Australia’s use of antibiotics.

22 Nov 2013

New documentary reveals how antiretroviral therapy transformed lives of HIV people in Africa

A new documentary produced by the University of East Anglia reveals how the lives of people with HIV in Africa have been transformed by antiretroviral therapy and highlights the crucial need for continued funding of the lifesaving treatment.

22 Nov 2013

First molecular test developed to detect eosinophilic esophagitis

Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis, a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago.

22 Nov 2013

Scientists hope to find new treatments for traumatic brain injury

In the most wide-reaching project of its kind, scientists at the University of Texas Medical Branch are expanding their research on traumatic brain injury, examining its progressive, chronic effects on the body in hopes of treating its immediate and long-term consequences. The project is funded by a three-year, $9 million grant from The Moody Foundation of Galveston.

22 Nov 2013

BonAlive Biomaterials launches osteostimulative BonAlive putty

BonAlive Biomaterials Ltd, a manufacturer of implantable medical devices, today announced the launch of a patented, ready-to-use and mouldable version of their osteostimulative BonAlive bioactive glass bone regeneration technology.

22 Nov 2013

Longer looks: Parents' crusade on rare diseases; fighting obesity; experts' view of alternative medicine

In the beginning, Chris Hempel noticed the clumsiness. Her girls tripped over toys on the floor. Their grandfather said he couldn't teach them to pedal their tricycles. … The Hempels learned of people who called themselves citizen-scientists. Many shared research papers and their day-to-day experience. Some talked of their willingness to try any promising drug. Others sought a role as equal partners with researchers. Scientists, while sympathetic, generally believe their work should be left to experts. Families are encouraged to raise money if they want to help, but the traditional view is that amateurs can't shape research or find cures. The Hempels found a maddening gap between the search for scientific knowledge and the search for treatments (Amy Docker Marcus, 11/2013).

22 Nov 2013

Chronic News and Research

Icahn School of Medicine receives $2.7M to investigate narrow pathway targeted immune therapy

Natural compound coumarins exhibit anti-inflammatory as well as anticoagulant activities

Dysregulation of epigenetic marks may play role in chronic kidney disease, shows study

New diabetes has little impact on outcomes in elderly hypertensives

Anti-epileptic drugs, bone loss and supplements

Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

Japanese health authorities approve Aerocrine's NIOX MINO for assessing airway inflammation

Scientists find link between airborne allergies and risk of blood cancers in women

UCSF investigator receives $89 M grant to research on anal cancer in people with HIV

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Chronic bronchitis could indicate COPD subtype

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

New bill offers hope to HIV patients on transplant waiting lists

Sinai Hospital reports results from Phase 2a trial of apo A-I infusion therapy CSL112

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

New documentary reveals how antiretroviral therapy transformed lives of HIV people in Africa

First molecular test developed to detect eosinophilic esophagitis

Scientists hope to find new treatments for traumatic brain injury

BonAlive Biomaterials launches osteostimulative BonAlive putty

Longer looks: Parents' crusade on rare diseases; fighting obesity; experts' view of alternative medicine

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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