Protein C News and Research

RSS

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Cassava could partially replace wheat flour in bread to prevent scarcity

In coming decades, the rise in global temperatures owing to climate change may hinder the production of wheat in many temperate regions where the crop is grown today. The raw material for bread, one of the world's most consumed foods, may become scarce and more expensive as a result.

25 Oct 2017

New blood test can reliably detect breast cancer in women with dense and non-dense breast tissue

A new study published in PLOS ONE demonstrates that Videssa® Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue. Nearly half of all women in the U.S. have dense breast tissue.

25 Oct 2017

UH professors developing new home test kit for kidney nephritis

With a four-year $1.4 million grant from the National Institutes of Health, two University of Houston engineering professors are developing a home test kit for kidney nephritis, or inflammation, in patients who have Systemic Lupus Erythematosus.

25 Oct 2017

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Patients with gallbladder cancer often show few or no symptoms for long periods of time. As a result, the tumors are only detected at a late stage of the disease when treatment is often no longer possible.

25 Oct 2017

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

A new class of drugs for blood cancers such as leukemia and multiple myeloma is showing promise. But it is hobbled by a problem that also plagues other cancer drugs: targeted cells can develop resistance.

25 Oct 2017

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Scientists discover 'molecular pencil sharpener' that releases powerful antibiotics

Picture a brand-new, unsharpened pencil. The graphite at its core can't be used for writing until a pencil sharpener chews away its wooden tip.

24 Oct 2017

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Genetically modified leaner pigs are on the cards soon. Researchers in china used the gene-editing technology, CRISPR, to create pigs that are less fatty and leaner with more muscle. This could mean genetically modified bacon on the plates.

24 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

New genetic variants contribute to the risk of breast cancer in women, study reveals

A new study reveals seventy-two novel genetic variants that are responsible for breast cancer risk. Published in the journals Nature and Nature Genetics, of these 72 variants, 65 are common variants that predispose patients to breast cancer and a further seven variants predispose particularly to estrogen -receptor negative breast cancer - the subcategory of cases that do not respond to hormonal treatments.

24 Oct 2017

Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells.

24 Oct 2017

Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

New drug offers hope for treatment of aggressive T-PLL leukemia

Hitherto there has been no adequate treatment available for the rare and highly aggressive malignant blood disease T-PLL leukemia.

24 Oct 2017

Study identifies protein that plays crucial role in diabetic retinopathy

For millions of Americans, their world is dissolving into an unrecognizable blur. Diabetic retinopathy is an eye disease affecting one-third of the estimated 30 million Americans who struggle with diabetes. As the patients' vision slowly fades, it never recovers and few treatments are available.

24 Oct 2017

Protein C News and Research

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Cassava could partially replace wheat flour in bread to prevent scarcity

New blood test can reliably detect breast cancer in women with dense and non-dense breast tissue

UH professors developing new home test kit for kidney nephritis

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Researchers discover mechanism that corrects protein misfolding in plants

Researchers mine blood-based epigenetic data to gain insights into autism biology

Scientists discover 'molecular pencil sharpener' that releases powerful antibiotics

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

APC gene mutations play dual role in development of colorectal cancer, research suggests

New genetic variants contribute to the risk of breast cancer in women, study reveals

Pollutant from forest and crop fires induces genetic damage in human lung cells

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

Research provides insight into how two stands of double helix separate during replication

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

New drug offers hope for treatment of aggressive T-PLL leukemia

Study identifies protein that plays crucial role in diabetic retinopathy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News