Protein C News and Research

RSS

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Melanomas caused by sun exposure have been matched with targeted treatments and immunotherapies, in many cases dramatically extending patients' lives. However, there are other kinds of melanoma not related to sun exposure and because they are caused by different genetic changes, they are not susceptible to the same targeted treatments.

23 Oct 2017

People with depressive symptoms before disaster may experience increase in inflammation

People who exhibit even a few depressive symptoms before a major life stressor, such as a disaster, may experience an increase in inflammation -- a major risk factor for heart disease and other negative health conditions -- after the event, according to new research from Rice University.

23 Oct 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Research could pave way to cure for type 2 diabetes

In healthy people, exosomes - tiny structures secreted by cells to allow intercellular communication - prevent clumping of the protein that leads to type 2 diabetes.

23 Oct 2017

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Many people associate the word "bacteria" with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. "The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens and educate our immune system on what to fight."

23 Oct 2017

Research provides insight on Y-shape in proteins associated with glaucoma

So unheard of was what researchers discovered in a protein associated with glaucoma that for over two years they ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially saw.

23 Oct 2017

Health scientists uncover gene linked to lung fibrosis

Health scientists at the University of Leicester and University of Nottingham have heralded the discovery of a gene associated with lung fibrosis as 'a potential new avenue of treatment for further research into this terrible disease.'

23 Oct 2017

RAND researchers estimate health care savings over next decade from biosimilars

Introducing "biosimilar" versions of complex biologic drugs used to treat illnesses such as cancer and rheumatoid arthritis could cut health care spending in the United States by $54 billion over the next decade, according to new analysis from the RAND Corporation.

23 Oct 2017

Osteocytes play crucial role as major source of RANKL during orthodontic tooth movement

Tokyo Medical and Dental University research team demonstrated that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor-κB ligand (RANKL), a protein crucial to bone remodeling.

23 Oct 2017

Study identifies predictors of poor outcomes in Duchenne muscular dystrophy patients

A new study from UT Southwestern suggests that more people with Duchenne muscular dystrophy could live longer by identifying and more aggressively treating patients with certain risk factors.

20 Oct 2017

New synthetic genetic tool measures and manipulates protein aggregation in live cells

A common thread ties seemingly unlinked disorders like Alzheimer's disease and type II diabetes together. This thread is known as protein aggregation and happens when proteins clump together. These complexes are a hallmark of many diseases but have recently been linked to beneficial functions as well.

20 Oct 2017

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked.

20 Oct 2017

New vaccine for pneumonia holds promise to save thousands of lives

In 2004, pneumonia killed more than 2 million children worldwide, according to the World Health Organization. By 2015, the number was less than 1 million.

20 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

Study unlocks complexities of cell death process that plays key role in health and disease

University of Pittsburgh scientists are unlocking the complexities of a recently discovered cell death process that plays a key role in health and disease, and new findings link their discovery to asthma, kidney injury, and brain trauma.

20 Oct 2017

Chromosomes may be entangled, research finds

Everyone knows that long bits of yarn, or charging cables and the like, tend to get quickly tangled and form nasty knots. Little is known about the structures of our genetic material, chromosomes, which also consist of long strings that -- according to our experience -- should be likely to become knotted. However, up to now it has not been possible to study this experimentally.

20 Oct 2017

Researchers discover new function in gene-regulatory protein

Researchers at Umeå and Stockholm universities in Sweden and Johns Hopkins University School of Medicine in the US have published a new study in the journal Molecular Cell.

20 Oct 2017

Protein identified as promising novel obesity treatment

This week Amgen published data showing that injection of a protein known as growth differentiation factor 15 (GDF15) facilitated weight loss in obese mice and primates.

20 Oct 2017

Protein C News and Research

Study finds lung cancer driver ALK-fusion in mucosal melanoma

People with depressive symptoms before disaster may experience increase in inflammation

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

Researchers discover new regulatory role for protein that links diet and disease

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Research could pave way to cure for type 2 diabetes

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Research provides insight on Y-shape in proteins associated with glaucoma

Health scientists uncover gene linked to lung fibrosis

RAND researchers estimate health care savings over next decade from biosimilars

Osteocytes play crucial role as major source of RANKL during orthodontic tooth movement

Study identifies predictors of poor outcomes in Duchenne muscular dystrophy patients

New synthetic genetic tool measures and manipulates protein aggregation in live cells

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

New vaccine for pneumonia holds promise to save thousands of lives

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

Study unlocks complexities of cell death process that plays key role in health and disease

Chromosomes may be entangled, research finds

Researchers discover new function in gene-regulatory protein

Protein identified as promising novel obesity treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News