Laboratory News and Research

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Paired exchange and incompatible kidney transplant program launched by UAB

Ann Marie Reynolds, a 32-year-old who has been in and out of hospitals fighting chronic kidney disease since she was a teenager, had a less than 1 percent chance of receiving a kidney without the University of Alabama at Birmingham's groundbreaking organ donation system that helped her and two other hard-to-match patients get kidneys in a three-way, incompatible kidney exchange earlier this year.

24 Dec 2013

Study finds link between genes affected by testosterone and antibody responses to influenza vaccine

A new study has identified a link between certain genes affected by testosterone and antibody responses to an influenza vaccine. The findings, published in Proceedings of the National Academy of Sciences, suggest that testosterone levels may partially explain why men often have weaker responses to vaccines than women.

24 Dec 2013

Changes to LZTR1 gene predispose people to develop schwannomas

Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature Genetics and led by researchers from the University of Alabama at Birmingham.

24 Dec 2013

Stakeholders agree that regulators not adequately prepared to manage risks posed by nanotechnology

Three stakeholder groups agree that regulators are not adequately prepared to manage the risks posed by nanotechnology, according to a paper published in the peer-reviewed journal PLOS One. In a survey of nano-scientists and engineers, nano-environmental health and safety scientists, and regulators, researchers at the UCSB Center for Nanotechnology in Society (CNS) and at the University of British Columbia found that those who perceive the risks posed by nanotechnology as "novel" are more likely to believe that regulators are unprepared.

23 Dec 2013

Research proves effectiveness of computerized neurocognitive testing for concussions

Computerized neurocognitive testing for concussions is widely used in amateur and professional sports, but little research over the past decade proves its effectiveness, a paper published this month in the journal Neuropsychology Review says.

23 Dec 2013

TSRI scientists identify compound that shows promise for treating obesity-linked diabetes

Scientists at The Scripps Research Institute (TSRI) have demonstrated a drug-discovery strategy with a double payoff-it enables the rapid selection of chemical compounds that have a desired effect on cells and also highlights how the compounds work.

23 Dec 2013

Engineered immune cells show antitumor activity in two patients with advanced cancers

Engineered immune cells, called CARTmeso cells, designed to direct antitumor immune responses toward tumors that carry a protein called mesothelin, showed antitumor activity in two patients with advanced cancers that had not responded to prior treatments, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

22 Dec 2013

Six common diseases arise from DNA changes, finds new research

Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions - for example, rheumatoid arthritis - has evaded scientists for years.

22 Dec 2013

Neuroscience researchers discover gene that controls response to cocaine

UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related strains of mice often used to study addiction and behavior patterns.

22 Dec 2013

ATS, Springer to collaborate on book series, Respiratory Medicine

Springer and the American Thoracic Society (ATS) have entered into a partnership to collaborate on the book series Respiratory Medicine.

20 Dec 2013

AMP proposes new, service-oriented terminology for high quality laboratory testing

The Association for Molecular Pathology (AMP) released a special article in the January 2014 issue of the Journal of Molecular Diagnostics titled "Revisiting Oversight and Regulation of Molecular-Based Laboratory-Developed Tests"(LDTs).

20 Dec 2013

Researchers discover way to identify artemisinin-resistant malaria

An international team of researchers has discovered a way to identify, at a molecular level, malaria-causing Plasmodium falciparum parasites that are resistant to artemisinin, the key drug for treating this disease.

20 Dec 2013

Submicrometer line focusing reduces protein crystal damage, enhances drug development

New recommendations for using X-rays promise to speed investigations aimed at understanding the structure and function of biologically important proteins - information critical to the development of new drugs.

20 Dec 2013

European research project to develop new rapid diagnostic devices

Led by the Basque R&D Alliance IK4, 13 organisations in 8 different countries have been conducting research for three years under the European LabOnFoil project to develop new rapid diagnostic devices.

19 Dec 2013

Tryton Medical launches Bifurcation Institute to advance care for bifurcated coronary artery disease

Tryton Medical, Inc., the leading developer of stents designed to treat bifurcation lesions, today announced the launch of the Bifurcation Institute. The Bifurcation Institute is a comprehensive education resource established to advance the standard of care for bifurcated coronary artery disease, a common, and often untreated, clinical need.

19 Dec 2013

Researchers use 3D technology from film industry to analyze rehabilitation for stroke patients

Researchers in Gothenburg have been using 3D technology from the film industry to analyze the everyday movements of stroke patients. The results, which are reported in a doctoral thesis at the Sahlgrenska Academy, indicate that computerized motion analysis increases our knowledge of how stroke patients can improve their ability to move through rehabilitation.

19 Dec 2013

LSDF announces research and development grants to commercialize health-related technologies

The Life Sciences Discovery Fund (LSDF) today announced $1.1 million in five Proof of Concept grants to Washington for-profit and non-profit organizations to foster the translation of health-related products from the laboratory into the commercial marketplace.

19 Dec 2013

Cells grown in ISS could help patients recover from stroke, says Mayo Clinic researcher

Abba Zubair, M.D., Ph.D, believes that cells grown in the International Space Station could help patients recover from a stroke, and that it may even be possible to generate human tissues and organs in space. He just needs a chance to demonstrate the possibility.

19 Dec 2013

Researchers discover series of compounds possessing anti-HIV activity

University of Minnesota researchers have discovered a first-of-its-kind series of compounds possessing anti-human immunodeficiency virus (HIV) activity. The compounds present a new target for potential HIV drug development and future treatment options.

18 Dec 2013

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

The Ben & Catherine Ivy Foundation today announced a $3 million grant to the Translational Genomics Research Institute (TGen), Nemucore Medical Innovations Inc., and Barrow Neurological Institute at St. Joseph's Hospital and Medical Center to help fund significant brain tumor research in Arizona.

18 Dec 2013

Laboratory News and Research

Paired exchange and incompatible kidney transplant program launched by UAB

Study finds link between genes affected by testosterone and antibody responses to influenza vaccine

Changes to LZTR1 gene predispose people to develop schwannomas

Stakeholders agree that regulators not adequately prepared to manage risks posed by nanotechnology

Research proves effectiveness of computerized neurocognitive testing for concussions

TSRI scientists identify compound that shows promise for treating obesity-linked diabetes

Engineered immune cells show antitumor activity in two patients with advanced cancers

Six common diseases arise from DNA changes, finds new research

Neuroscience researchers discover gene that controls response to cocaine

ATS, Springer to collaborate on book series, Respiratory Medicine

AMP proposes new, service-oriented terminology for high quality laboratory testing

Researchers discover way to identify artemisinin-resistant malaria

Submicrometer line focusing reduces protein crystal damage, enhances drug development

European research project to develop new rapid diagnostic devices

Tryton Medical launches Bifurcation Institute to advance care for bifurcated coronary artery disease

Researchers use 3D technology from film industry to analyze rehabilitation for stroke patients

LSDF announces research and development grants to commercialize health-related technologies

Cells grown in ISS could help patients recover from stroke, says Mayo Clinic researcher

Researchers discover series of compounds possessing anti-HIV activity

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

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