Chronic News and Research

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Research findings may offer clues to help prevent stress-related health problems

Researchers hope to discover why some people struggle with their spirituality or religious beliefs and practices in the face of life's challenges while others don't.

13 Nov 2013

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

Study on MRIUS-guided prostate biopsy wins first prize for best poster at EAU13th CEM

Using Magnetic Resonance Imaging-Ultrasound (MRIUS)- guided prostate biopsy has high sensitivity to detect prostate abnormalities compared with transrectal ultrasonography (TRUS biopsy) of MRI positive findings.

13 Nov 2013

Researchers use bioelectrical impedance analysis ratios to assess Lymphedema in breast cancer patients

Viewed as one of the most feared outcomes of breast cancer treatment, doctors struggle detecting and diagnosing breast-cancer related Lymphedema--a condition affecting the lymphatic system and causing psychosocial distress and physical challenges for patients.

13 Nov 2013

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Collaborating with researchers from the Northwestern University Feinberg School of Medicine in Chicago, a research team at Wayne State University's School of Medicine led by Kezhong Zhang, Ph.D., has contributed to an important discovery in the inflammatory stress mechanism and specific inhibitor for the treatment of rheumatoid arthritis.

13 Nov 2013

Study outlines “sobering reality” of the U.S. health care system

Over the last decade, the biggest driver of the high health care costs in the United States has been neither the aging of the population nor the large numbers of tests and treatments being prescribed.

13 Nov 2013

Study explains why south Asians have high susceptibility to developing type 2 diabetes

Lower amounts of brown adipose tissue (BAT, or ‘brown fat’) could help explain why south Asians—who make up a fifth of the world’s population—have an exceptionally high susceptibility to developing metabolic problems such as obesity and type 2 diabetes.

13 Nov 2013

People suffering from chronic pain, emotional distress likely to receive long-term opioid therapy

People suffering from chronic non-cancer pain and severe emotional distress, such as depression, anxiety and substance use, are likely to receive long-term opioid therapy despite a lack of evidence that this treatment helps, reports a new review in General Hospital Psychiatry.

13 Nov 2013

African Americans with APOL1 gene variant experience faster progression of CKD

A large study co-authored by Penn Medicine published this week in the New England Journal of Medicine found that African Americans with the APOL1 gene variant experience faster progression of chronic kidney disease and have a significantly increased risk of kidney failure, regardless of their diabetes status.

13 Nov 2013

Studies suggest novel therapies for nicotine, heroin and gambling addiction

Studies released today suggest promising new treatments for nicotine and heroin addiction, and further our understanding of pathological gambling and heroin abuse in those suffering chronic pain.

12 Nov 2013

Novel approach confirms dysfunctional energy production in schizophrenia

A method of directly assessing creatine kinase in the brain provides “direct and compelling” evidence for abnormal bioenergetics in the brains of patients with schizophrenia, say the study authors.

12 Nov 2013

Hebrew University to participate in new European research project on chronic pain

The Hebrew University of Jerusalem is one of 11 universities, medical centers and research institutes in seven countries participating in ncRNAPain, a new European research project that aims at further exploring the biological mechanisms underlying chronic pain.

12 Nov 2013

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Northwestern Medicine- scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.

12 Nov 2013

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that it has filed an investigational new drug application with the US Food and Drug Administration to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease.

12 Nov 2013

Researchers discover new pathway for treating allergic diseases

A collaboration among researchers in Israel and the United States has resulted in the discovery of a new pathway that has broad implications for treating allergic diseases - particularly eosinophil-associated disorders.

12 Nov 2013

Researchers discovers key genetic culprit responsible for growth, metastasis of colon cancer

Chronic inflammation has long been known as a key risk factor for cancer---particularly colon cancer---but the exact mechanisms of how inflammation heightens the immune response, and ultimately influences the initiation and progression of cancer have remained elusive.

12 Nov 2013

Obesity in older women linked with higher risk of death, disability, disease before age of 85

Obesity and a bigger waist size in older women are associated with a higher risk of death, major chronic disease and mobility disability before the age of 85, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

12 Nov 2013

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

An antibody to a protein critical to enabling the brain to talk to muscles has been identified as a cause of myasthenia gravis, researchers report.

12 Nov 2013

Occupational therapist receives $1M grant to develop virtual world programs that help amputees improve skills

Some people use alternate virtual world programs like Second Life- to escape reality, but one researcher is examining whether these same virtual worlds that are used to stimulate the imagination could help amputees develop the skills needed to navigate the real world.

11 Nov 2013

ICS overuse warning in COPD

Researchers from the UK caution that inhaled corticosteroids are being overused in patients with chronic obstructive pulmonary disease, in light of a lack of solid evidence for their efficacy, limited guideline support, and growing concerns over their association with pneumonia.

11 Nov 2013

Chronic News and Research

Research findings may offer clues to help prevent stress-related health problems

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

Study on MRIUS-guided prostate biopsy wins first prize for best poster at EAU13th CEM

Researchers use bioelectrical impedance analysis ratios to assess Lymphedema in breast cancer patients

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Study outlines “sobering reality” of the U.S. health care system

Study explains why south Asians have high susceptibility to developing type 2 diabetes

People suffering from chronic pain, emotional distress likely to receive long-term opioid therapy

African Americans with APOL1 gene variant experience faster progression of CKD

Studies suggest novel therapies for nicotine, heroin and gambling addiction

Novel approach confirms dysfunctional energy production in schizophrenia

Hebrew University to participate in new European research project on chronic pain

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Researchers discover new pathway for treating allergic diseases

Researchers discovers key genetic culprit responsible for growth, metastasis of colon cancer

Obesity in older women linked with higher risk of death, disability, disease before age of 85

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

Occupational therapist receives $1M grant to develop virtual world programs that help amputees improve skills

ICS overuse warning in COPD

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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