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UC Santa Barbara extends research contract with Army Research Laboratory

UC Santa Barbara's Institute for Collaborative Biotechnologies has received an extension of its contract with the U.S. Army Research Laboratory-Army Research Office, providing an additional $48 million over three years to support research that is inspired by biological systems. The continuation in ICB funding speaks to the success of a decade of fundamental research in the areas of biotechnology, chemistry, engineering, physics, materials science, computer science, neuroscience and medicine.

9 Dec 2013

Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans.

9 Dec 2013

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Researchers have uncovered a potential biological factor that may contribute to disparities in prostate cancer incidence and mortality between African-American and non-Hispanic white men in the United States, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Scientists identify important new genes for epilepsy

Scientists screening the DNA of large cohorts for known and suspected epilepsy associated genes are finding that, while some genes are implicated in discrete phenotypes or forms of epilepsy, other genes are implicated in a wider range of phenotypes. Although ion channel genes are a common cause of epilepsy, the researchers also report a significant number of epilepsy patients with mutations in non-ion channel genes. The studies have important implications for treatment, prognosis and risk counseling.

9 Dec 2013

Researchers find how olfactory receptor variation impacts human odor perception

According to Gertrude Stein, "A rose is a rose is a rose," but new research indicates that might not be the case when it comes to the rose's scent. Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.

9 Dec 2013

Researchers find huge diversity in how different organisms age

In our youth we are strong and healthy and then we weaken and die - that's probably how most would describe what ageing is all about. But, in nature, the phenomenon of ageing shows an unexpected diversity of patterns and is altogether rather strange, conclude researchers from The University of Southern Denmark.

9 Dec 2013

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain.

9 Dec 2013

Scientists target protein-detection approach to systematically measure human repertoire of proteins

An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.

9 Dec 2013

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Edvard and May-Britt Moser of the Norwegian University of Science and Technology (NTNU), and John O'Keefe, from University College London have been awarded the 2013 Louisa Gross Horwitz Prize for discoveries that have illuminated how the brain calculates location and navigation.

9 Dec 2013

Skin is capable of communicating with liver, say researchers

Researchers from the University of Southern Denmark have discovered that the skin is capable of communicating with the liver. The discovery has surprised the scientists, and they say that it may help our understanding of how skin diseases can affect the rest of the body.

9 Dec 2013

Gene discovered to play a part in one per cent of all cancers

Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.

9 Dec 2013

Scientists recommend testing for Pearson syndrome in patients with congenital anemia

Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

8 Dec 2013

Novel device may simplify monitoring of patients' response to treatment for ovarian cancer

A microchip-based device developed by Massachusetts General Hospital investigators may greatly simplify the monitoring of patients' response to treatment for ovarian cancer - the most lethal form of gynecologic cancer - and certain other malignancies.

6 Dec 2013

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Kolltan Pharmaceuticals, a privately held biopharmaceutical company, today announced the Company has signed a license agreement with the University of Toronto for novel anti-KIT receptor tyrosine kinase antibodies identified in the laboratories of Dr. Sachdev Sidhu at the University of Toronto and the laboratory of Dr. Joseph Schlessinger of Yale University.

6 Dec 2013

Ancon Technologies unveils new cancer-screening device

Ancon Technologies, a company devoted to finding new ways to beat cancer, recently unveiled a new cancer-screening device to the public, the NBT detector. The company's latest product aims to bring cancer detection to the next level: it uses Nanoparticle Biomarker Tagging technology to identify cancer biomarkers in exhaled air.

6 Dec 2013

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Avian influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect humans easily, according to a new study by scientists at The Scripps Research Institute. In contrast to some initial studies that had suggested that H7N9 poses an imminent risk of a global pandemic, the new research found, based on analyses of virus samples from the Chinese outbreak, that H7N9 is still mainly adapted for infecting birds, not humans.

6 Dec 2013

Scientists to deliver lecture on innovations in chemistry at ACS meeting

One scientist is developing breakthrough electronic sutures and medical implants that dissolve when their jobs are done. Another is a pioneer in the field of energy conversion that could lead to development of high-performance solar cells and new types of electronic devices that could integrate into the body.

6 Dec 2013

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

6 Dec 2013

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Today Biocartis and VIB announced their exclusive license agreement on a novel panel of microsatellite instability biomarkers for several cancers, in particular colorectal cancer.

From Biocartis 6 Dec 2013

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

A group of University of Illinois researchers, led by Centennial Chair Professor of the Department of Chemical and Biomolecular Engineering Huimin Zhao, has demonstrated the use of an innovative DNA engineering technique to discover potentially valuable functions hidden within bacterial genomes.

6 Dec 2013

Laboratory News and Research

UC Santa Barbara extends research contract with Army Research Laboratory

Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Scientists identify important new genes for epilepsy

Researchers find how olfactory receptor variation impacts human odor perception

Researchers find huge diversity in how different organisms age

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Scientists target protein-detection approach to systematically measure human repertoire of proteins

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Skin is capable of communicating with liver, say researchers

Gene discovered to play a part in one per cent of all cancers

Scientists recommend testing for Pearson syndrome in patients with congenital anemia

Novel device may simplify monitoring of patients' response to treatment for ovarian cancer

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Ancon Technologies unveils new cancer-screening device

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Scientists to deliver lecture on innovations in chemistry at ACS meeting

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

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