Laboratory News and Research

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Topokine initiates Phase 2 clinical trial of XAF5 Gel for double chin treatment

Topokine Therapeutics has initiated dosing in a Phase 2, randomized controlled clinical trial of XAF5 Gel for reduction of excess submental fat, commonly known as "double chin." XAF5 Gel is a proprietary skin formulation of a compound already known to reduce fat around the human eye. Study participants are applying XAF5 Gel or placebo once a night to skin under the chin.

20 Nov 2013

Penn researchers advance towards new DNA sequencing technique using graphene nanoribbon

The instructions for building all of the body's proteins are contained in a person's DNA, a string of chemicals that, if unwound and strung end to end, would form a sentence 3 billion letters long. Each person's sentence is unique, so learning how to read gene sequences as quickly and inexpensively as possible could pave the way to countless personalized medical applications.

19 Nov 2013

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

A multicenter team of researchers within the NIH-funded Cardiothoracic Surgical Trials Network, led by Icahn School of Medicine at Mount Sinai, have found end-stage heart failure patients who receive a surgically implanted left ventricular assist device heart pump may also benefit from a single dose of millions of powerful cells injected directly into their heart during surgery.

19 Nov 2013

Scientists at Salk Institute develop novel platform to study kidney diseases

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

19 Nov 2013

University of Wisconsin scientist to present revolutionary stem cell technology to Australian bioindustry

Internationally recognised stem cell scientist, Associate ProfessorIgor Slukvin, University of Wisconsin – Madison, is visiting Australia as the key-note speaker at a Stem Cell Meeting and Workshop in Sydney next week.

19 Nov 2013

New technology to give voice to people with severe speech impairment

The first speech recognition aid to give a voice to people with severe speech impairment is the flagship technology on display today [19 November] at the launch of the University of Sheffield’s new Centre for Assistive Technology and Connected Healthcare.

19 Nov 2013

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Findings may help scientists better understand prognosis of advanced prostate cancer

Many patients diagnosed with prostate cancer have indolent, slow-growing forms of the disease that are not life-threatening. However, more than 30,000 American men will die from aggressive prostate cancer this year alone. This sharp contrast between low-risk and aggressive disease presents a challenge for many researchers and physicians as they diagnose patients and also determine the prognosis of the men with the most aggressive forms of prostate cancer.

19 Nov 2013

New method could cut hours off the time it takes to diagnose blood infections

A new method could cut hours off the time it takes to diagnose blood infections while also eliminating the need for complicated manual processing and expensive equipment, according to a report to be published in mBio-, the online open-access journal of the American Society for Microbiology, on November 19.

19 Nov 2013

OSU researchers make breakthrough in solving 50-year-old problem in hearing technology

Computer engineers and hearing scientists at The Ohio State University have made a potential breakthrough in solving a 50-year-old problem in hearing technology: how to help the hearing-impaired understand speech in the midst of background noise.

19 Nov 2013

Layers of skin that form first line of defence in body's fight against infection reveal secret

The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret.

19 Nov 2013

Cranberries' unique bioactive compounds improve heart health and temper inflammation

Cranberries are more than a holiday favorite, given their remarkable nutritional and health benefits. A new research review published in the international journal Advances in Nutrition provides reasons why these tiny berries can be front and center and not just a side dish. The review authors conclude that cranberries provide unique bioactive compounds that may help reduce the incidence of certain infections, improve heart health and temper inflammation.

19 Nov 2013

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called 'PRH', is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.

19 Nov 2013

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer.

19 Nov 2013

Researchers solve structure of key protein in Nipah virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses.

18 Nov 2013

Habitual dietary intake of monozygotic twins associated with fecal microbiota composition

The establishment of microbial populations in the gastrointestinal-tract is a complex process, involving microbial and host interactions eventually resulting in a dense and stable population.

18 Nov 2013

Researchers take close look at medicine's highest volume activity

Laboratory testing is health care's single highest volume activity, with over 5 billion tests performed each year in the U.S.

18 Nov 2013

Close to 100 novel human gene regions that code for proteins may be linked to cancer

By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.

18 Nov 2013

Researchers develop more accurate way to calculate "bad" cholesterol

Johns Hopkins researchers have developed a more accurate way to calculate low-density lipoprotein (LDL) cholesterol, the so-called "bad" form of blood fat that can lead to hardening of the arteries and increase the risk of heart attack and stroke.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

18 Nov 2013

Laboratory News and Research

Topokine initiates Phase 2 clinical trial of XAF5 Gel for double chin treatment

Penn researchers advance towards new DNA sequencing technique using graphene nanoribbon

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

Scientists at Salk Institute develop novel platform to study kidney diseases

University of Wisconsin scientist to present revolutionary stem cell technology to Australian bioindustry

New technology to give voice to people with severe speech impairment

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Findings may help scientists better understand prognosis of advanced prostate cancer

New method could cut hours off the time it takes to diagnose blood infections

OSU researchers make breakthrough in solving 50-year-old problem in hearing technology

Layers of skin that form first line of defence in body's fight against infection reveal secret

Cranberries' unique bioactive compounds improve heart health and temper inflammation

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Researchers solve structure of key protein in Nipah virus

Habitual dietary intake of monozygotic twins associated with fecal microbiota composition

Researchers take close look at medicine's highest volume activity

Close to 100 novel human gene regions that code for proteins may be linked to cancer

Researchers develop more accurate way to calculate "bad" cholesterol

Researchers generate three-dimensional kidney structures from human stem cells

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