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New method for estimating LDL-C levels more accurate than standard measure

Seth S. Martin, M.D., of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, and colleagues developed a method for estimating low-density lipoprotein cholesterol (LDL-C) levels that is more accurate than the standard measure.

18 Nov 2013

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Arvin Dar, PhD, structural and chemical biologist in oncological sciences at the Icahn School of Medicine at Mount Sinai, is one of 41 national recipients of the prestigious National Institutes of Health (NIH) Director's New Innovator Awards for High-Risk, High Reward Research. The award will support Dar's research into Ras-dependent cancers, specifically investigating how to combat mutations in Ras, a protein implicated in at least one of every five cancers.

16 Nov 2013

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

A new five-year, $23.8 million National Institutes of Health (NIH) grant will support a multi-center, multidisciplinary study on a deadly bleeding syndrome - called coagulopathy - that occurs without warning in some trauma patients.

16 Nov 2013

Scientists join patients to address Friedreich's Ataxia

The Spanish Federation of Ataxia (FEDAES)—in representation of the GENEFA Platform for a Friedreich's Ataxia cure—, the Babel Family association for biomedical research into Friedreich's Ataxia, the "Centro de Biología Molecular Severo Ochoa" (CMBSO), and the Institute for Research in Biomedicine (IRB Barcelona) have signed an agreement through which these patients' associations will fund, by means of donations, a 3-year research project addressing Friedreich's Ataxia.

16 Nov 2013

Former status as elite athlete reduces risk of type 2 diabetes later in life

A study of almost 400 former elite male athletes shows that former status as an elite athlete reduces the risk of developing type 2 diabetes in later life by 28%. The research appears in Diabetologia, the journal of the European Association for the Study of Diabetes, and is by Dr Merja Laine, University of Helsinki, Helsinki, Finland, and colleagues.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

Bleach solution could provide new way to treat skin damage

Processes that age and damage skin are impeded by dilute bleach solution, according to a new study by researchers at the Stanford University School of Medicine.

16 Nov 2013

Study: Surgical weight loss may be able to reverse the effects of aging

Stanford University researchers say surgical weight loss may turn back the effects of aging at a genetic level, in the first study* of its kind presented here during ObesityWeek 2013, the largest international event focused on the basic science, clinical application and prevention and treatment of obesity.

16 Nov 2013

Zafgen presents safety, efficacy data from beloranib Phase 2 study at Obesity Week 2013

Zafgen, Inc., a leading biopharmaceutical company dedicated to addressing the unmet needs of severely obese patients, today announced final efficacy and safety data from its recently completed Phase 2 study of beloranib, a selective inhibitor of methionine aminopeptidase 2.

15 Nov 2013

Early detection of breast cancer could soon be possible with blood test

What could someday be the first blood test for the early detection of breast cancer was shown in preliminary studies to successfully identify the presence of breast cancer cells from serum biomarkers, say the Houston Methodist Research Institute scientists who are developing the technology.

15 Nov 2013

Study finds consistent sleep pattern can reduce risk of illness among adolescents

Newly released findings from Bradley Hospital published in the Journal of Sleep Research have found that acute illnesses, such as colds, flu, and gastroenteritis were more common among healthy adolescents who got less sleep at night. Additionally, the regularity of teens' sleep schedules was found to impact their health.

15 Nov 2013

Researchers exploit power of evolution to create new drug for use against heart disease

An international team of researchers led by the University of Leicester has "harnessed the power of evolution" to create a new drug for possible use against heart disease, inflammation and other illnesses.

15 Nov 2013

Kaiser Permanente to open doors to brand new specialty center in Lone Tree, Colorado

After years of planning, construction and preparation, Kaiser Permanente will open the doors to a brand new specialty center in Lone Tree on December 2nd. This is the largest construction project and the most significant addition to the health plan's brick-and-mortar presence in Colorado in nearly a decade.

15 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

FDA approves ibrutinib for treatment of mantle cell lymphoma

Today's U.S. Food and Drug Administration approval of ibrutinib to treat patients with mantle cell lymphoma is a significant advance for patients with this blood cancer. It was approved as a single agent for treatment of patients with MCL who have received at least one prior therapy.

14 Nov 2013

Diagnosing influenza with rapid tests leads to more efficient care

When patients in the emergency department (ED) are diagnosed with influenza by means of a rapid test, they get fewer unnecessary antibiotics, are prescribed antiviral medications more frequently, and have fewer additional lab tests compared to patients diagnosed with influenza without testing, according to a new study. Published online in the Journal of the Pediatrics Infectious Diseases Society, the findings suggest that diagnosing influenza with a rapid diagnostic test leads to more appropriate, specific, and efficient care.

14 Nov 2013

Study reveals how cocaine permanently damages proteins in the body

A new study on cocaine, the notorious white powder illegally snorted, injected or smoked by nearly 2 million Americans, details how it may permanently damage proteins in the body. That information, gleaned from laboratory tests, could be used to potentially detect the drug in biofluids for weeks or months - instead of days - after use, say scientists. The findings, which appear in the ACS journal Chemical Research in Toxicology, could also help explain cocaine's long-term health effects.

14 Nov 2013

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

Researchers at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai have successfully tested a powerful gene therapy, delivered directly into the heart, to reverse heart failure in large animal models.

14 Nov 2013

Groundbreaking study reveals novel approach to treat, eliminate MRSA infection

Recent work from University Distinguished Professor of Biology Kim Lewis promises to overcome one of the leading public health threats of our time. In a groundbreaking study published Wednesday in the journal Nature, Lewis' team presents a novel approach to treat and eliminate methicillin resistant staphylococcus aureus, or MRSA, a potent bacterium whose resistance to antibiotics has kept it one step ahead of researchers.

14 Nov 2013

Laboratory News and Research

New method for estimating LDL-C levels more accurate than standard measure

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

$23.8M NIH grant supports multi-center, multidisciplinary study on deadly bleeding syndrome

Scientists join patients to address Friedreich's Ataxia

Former status as elite athlete reduces risk of type 2 diabetes later in life

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

Bleach solution could provide new way to treat skin damage

Study: Surgical weight loss may be able to reverse the effects of aging

Zafgen presents safety, efficacy data from beloranib Phase 2 study at Obesity Week 2013

Early detection of breast cancer could soon be possible with blood test

Study finds consistent sleep pattern can reduce risk of illness among adolescents

Researchers exploit power of evolution to create new drug for use against heart disease

Kaiser Permanente to open doors to brand new specialty center in Lone Tree, Colorado

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

FDA approves ibrutinib for treatment of mantle cell lymphoma

Diagnosing influenza with rapid tests leads to more efficient care

Study reveals how cocaine permanently damages proteins in the body

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

Groundbreaking study reveals novel approach to treat, eliminate MRSA infection

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