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Next-generation sequencing may help discover genetic changes that might lead to cancer

A pilot study led by the Translational Genomics Research Institute and the Virginia G. Piper Cancer Center at Scottsdale Healthcare shows that, even for patients with advanced and rapidly transforming cancer, researchers can find potential therapeutic targets using the latest advances in genomic sequencing.

31 Oct 2013

Mediterranean diet exerts greater cardioprotective effect than low-fat diet, shows study

The Nutrition and Obesity Research Group of the UPV/EHU-University of the Basque Country is studying the effects of diet composition on people's body weight and health. Its participation in the PREDIMED project features among the many pieces of research it has conducted.

30 Oct 2013

High-definition transcranial direct current stimulation helps treat pain in fibromyalgia patients

Imagine significantly reducing a persistent migraine or fibromyalgia by a visit to a doctor who delivers low doses of electricity to the brain.

30 Oct 2013

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

One of the commonest parasites in the world is Toxoplasma gondii. Toxoplasma can infect most warm-blooded animals, including humans, and causes significant damage to the unborn child if a woman becomes infected for the first time during pregnancy.

30 Oct 2013

Researchers identify new drug for treating irritable bowel syndrome with constipation

An international team led by University of Adelaide researchers has identified the mechanism of pain relief of a new drug for treating Irritable Bowel Syndrome with Constipation (IBS-C), based on nonclinical studies, and quantified its effectiveness in pain relief in human trials.

30 Oct 2013

Seward releases new online Resource Centre for microbiological analyses

Seward Ltd., manufacturers of the world leading range of Stomacher paddle blenders and Stomacher® accessories used in sample preparation for microbiological analyses, has introduced a new application focused Resource Centre within its website – www.seward.co.uk.

29 Oct 2013

Mount Sinai cardiologists use FDA-approved device for severely calcified coronary arteries

Leading interventional cardiologists at The Mount Sinai Hospital are the first in the world to use a newly U.S. Food and Drug Administration approved device for the treatment of severely calcified coronary arteries before the placement of a cardiac stent to open a blocked artery.

29 Oct 2013

New understanding of sperm capacitation may improve IVF success rates

Two new papers from reproductive biologists at the University of Massachusetts Amherst, with international partners, report advances in understanding the basic processes of sperm capacitation that may one day improve success rates of in vitro fertilization (IVF) by providing a shortcut to bypass problems, and may eventually lead to a male contraceptive.

29 Oct 2013

WUSTL's Igor Efimov studies new potential treatment for irregular heartbeat

Although an irregular heartbeat is a common malady in the United States, affecting an estimated 5 million people, the treatments for it are limited in scope and effectiveness.

29 Oct 2013

Palliative care often errantly reduced to end-of-life care

Palliative care, a specialized, multidisciplinary team approach to caring for seriously ill people and their families, is often errantly reduced to end-of-life care. This misconception has led to palliative care involvement being introduced late in an illness, often depriving patients and their families of comprehensive symptom control, support and assistance with complex decision-making throughout the course of their illness when it could provide the most benefit.

29 Oct 2013

Research findings could help define new vaccination applications

New research from the Masonic Cancer Center, University of Minnesota, and the University of Minnesota Center for Immunology has identified key proteins that influence immune response strategies, a finding that could influence new vaccination approaches.

29 Oct 2013

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University. "Because they also lower cholesterol levels, they are extensively used in the food industry and as dietary supplements."

25 Oct 2013

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Nanyang Technological University (NTU) today launched a new electron microscopy lab led by world renowned scientist Professor Daniela Rhodes. Named the NTU Cryo-Electron Microscopy Laboratory, it is also the world's first university research facility to be equipped with an advanced cryo transmission electron microscope fitted with the latest detector/camera ten times more sensitive than a regular electron microscopy camera.

25 Oct 2013

Viewpoints: Republicans new-found interest in the workings of the health website; fixing the problem crucial to Obama's presidency

Republicans are apoplectic about Healthcare.gov, the official Web site for the Affordable Care Act. They are trying desperately to change the subject from their disastrous government shutdown by ranting about the failures of a government Web site that cost a tiny fraction of what was lost as a result of the shutdown. Republicans are pretending that they care about the problems encountered in signing up for a system that many of them are bent on destroying (Charles M. Blow, 10/23).

25 Oct 2013

Johns Hopkins joins with imec to advance silicon applications in health care

Researchers and physicians at The Johns Hopkins University will collaborate with Belgian nanoelectronics research center imec to advance silicon applications in health care, beginning with development of a point-of-care device to enable a broad range of clinical tests to be performed outside the laboratory.

25 Oct 2013

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome.

25 Oct 2013

Hypoxia can be detected prior to incapacitating physical symptoms, say researchers

A team of Mayo Clinic researchers have found that hypoxia can be detected prior to incapacitating physical symptoms which can be a safety threat at high altitudes. The findings were published as the lead article in the October issue of Aviation, Space, and Environmental Medicine.

25 Oct 2013

Researchers measure stiffness of ankle using "Anklebot" robot

For most healthy bipeds, the act of walking is seldom given a second thought: One foot follows the other, and the rest of the body falls in line, supported by a system of muscle, tendon, and bones.

25 Oct 2013

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

An international team of scientists has identified an association between heritable, rare mutations in the RINT1 gene and increased risk of early onset breast cancer, according to research reported today (Oct. 24) at the American Society of Human Genetics 2013 annual meeting in Boston.

25 Oct 2013

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

Parkinson's disease continues to puzzle physicians and biologists alike - even though it is well-established that symptoms like muscle tremors, rigidity, and, during the final stages, immobility can all be traced back to the death of a certain type of brain cell called a dopaminergic neuron. The underlying cause of this cellular death is a complex web of interrelated genetic molecular processes as well as external factors, most of the details of which are well-known. But how the various factors correlate and influence each other continues to elude the scientific community.

24 Oct 2013

Laboratory News and Research

Next-generation sequencing may help discover genetic changes that might lead to cancer

Mediterranean diet exerts greater cardioprotective effect than low-fat diet, shows study

High-definition transcranial direct current stimulation helps treat pain in fibromyalgia patients

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

Researchers identify new drug for treating irritable bowel syndrome with constipation

Seward releases new online Resource Centre for microbiological analyses

Mount Sinai cardiologists use FDA-approved device for severely calcified coronary arteries

New understanding of sperm capacitation may improve IVF success rates

WUSTL's Igor Efimov studies new potential treatment for irregular heartbeat

Palliative care often errantly reduced to end-of-life care

Research findings could help define new vaccination applications

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Viewpoints: Republicans new-found interest in the workings of the health website; fixing the problem crucial to Obama's presidency

Johns Hopkins joins with imec to advance silicon applications in health care

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

Hypoxia can be detected prior to incapacitating physical symptoms, say researchers

Researchers measure stiffness of ankle using "Anklebot" robot

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

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