Chronic News and Research

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Mild COPD phenotype discovery offers treatment hope

Research indicates that smokers with and without mild chronic obstructive pulmonary disease can be classified into distinct phenotypes on the basis of computed tomography findings.

23 Sep 2013

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

Novartis announced today that the European Commission approved once-daily Ultibro® Breezhaler® (indacaterol 85 mcg / glycopyrronium 43 mcg) as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD). In addition, the Japanese Ministry of Health, Labour and Welfare (MHLW) approved once-daily Ultibro® Inhalation Capsules (glycopyrronium 50 mcg / indacaterol 110 mcg), delivered through the Breezhaler® device, for relief of various symptoms due to airway obstruction in chronic obstructive pulmonary disease (COPD). Ultibro® Breezhaler® / Ultibro® Inhalation Capsules were developed under the name QVA149.

23 Sep 2013

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Janssen Biotech, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved STELARA® (ustekinumab) alone or in combination with methotrexate for the treatment of adult patients (18 years or older) with active psoriatic arthritis.

23 Sep 2013

Undersize school chairs, low desks and overweight backpacks contribute to chronic back pain in adolescents

Undersize school chairs, low desks and overweight backpacks are contributing to chronic back pain in adolescents, according to a study from researchers in Portugal to be published in the International Journal of Human Factors and Ergonomics.

23 Sep 2013

Older women with newly diagnosed breast cancer are more likely to experience functional disability

Many older women with newly diagnosed breast cancer have difficulty accomplishing daily tasks, and African-Americans seem to be disproportionately affected.

23 Sep 2013

Study explains why survival is low in peritoneal dialysis patients

Clinicians and scientists from Keele and Cardiff universities have published data from a landmark study that explains why survival in patients on peritoneal dialysis is low.

23 Sep 2013

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Ablynx and AbbVie today announced that they have entered into a global license agreement to develop and commercialize the anti-IL-6R Nanobody, ALX-0061, to treat inflammatory diseases.

23 Sep 2013

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood.

23 Sep 2013

Research roundup: 'Cadillac' plan taxes; 'chronic care management' for substance abusers; long-term care services

As health coverage expands to tens of millions of Americans--through Medicaid expansion in states and the new state health insurance exchanges that will soon begin selling individual health coverage--some Americans with employer-sponsored health coverage are seeing their benefits decrease.

21 Sep 2013

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

The University of North Carolina at Chapel Hill received two separate grants from the U.S. Food and Drug Administration and the National Institutes of Health today as part of an on-going interagency partnership. UNC will house two of 14 Tobacco Centers of Regulatory Science, which are receiving a total of up to $53 million for tobacco-related research in fiscal year 2013.

21 Sep 2013

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin analogs and phosphodiesterase 5 inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension.

21 Sep 2013

Regular reminders improve preventative screening for primary care patients

Regular reminders for health care providers and patients to schedule preventative health screening tests and procedures resulted in improved provider performance in ordering overdue preventative screening for primary care patients, according to research published in the September special issue "Emerging Models of Care and Payment Delivery" of the Journal for Healthcare Quality, the peer-reviewed publication of the National Association for Healthcare Quality (NAHQ), www.nahq.org.

21 Sep 2013

Natural eradication of Helicobacter from human populations

Gut-dwelling bacteria are attracting increasing attention, particularly those associated with human diseases. Helicobacter pylori is found in the stomach of humans, where it may cause chronic gastritis and gastric ulcers, although the majority of infections are asymptomatic.

21 Sep 2013

MRE imaging technique accurately detects chronic liver disease in children

A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.

21 Sep 2013

Viewpoints: Rove warns GOP that defunding could be 'self-defeating;' Jonathan Cohn says latest Obamacare fight reveals Republicans' will to overlook gains from law

Today, independents look more like Republicans than Democrats, especially when it comes to health care. In a new Crossroads GPS health-care policy survey conducted in 10 states likely to have competitive Senate races and in House districts that lean Republican or are swing seats, 60 percent of independents oppose President Obama's Affordable Care Act. If this holds through 2014, then Republicans should receive another big boost in the midterms. There is, however, one issue on which independents disagree with Republicans: using the threat of a government shutdown to defund ObamaCare (Karl Rove, 9/18).

20 Sep 2013

Chronic News and Research

Mild COPD phenotype discovery offers treatment hope

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Undersize school chairs, low desks and overweight backpacks contribute to chronic back pain in adolescents

Older women with newly diagnosed breast cancer are more likely to experience functional disability

Study explains why survival is low in peritoneal dialysis patients

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Research roundup: 'Cadillac' plan taxes; 'chronic care management' for substance abusers; long-term care services

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Regular reminders improve preventative screening for primary care patients

Natural eradication of Helicobacter from human populations

MRE imaging technique accurately detects chronic liver disease in children

Viewpoints: Rove warns GOP that defunding could be 'self-defeating;' Jonathan Cohn says latest Obamacare fight reveals Republicans' will to overlook gains from law

Older adults who gain little weight live longer

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Now is the best time to get immunized against influenza, says UAB expert

Study explains indirect burden of malaria on childhood deaths

Intentional weight loss can have positive health benefits in older adults

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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