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Pregabalin drug can help reduce incidence of chronic pain following cardiac surgery

The incidence of chronic pain following cardiac surgery can be reduced in patients when the drug pregabalin is used before surgery and for 14 days post-surgery, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Researchers discover new approach to tackle global threat of antibiotic drug resistance

Researchers at McMaster University are addressing the crisis in drug resistance with a novel approach to find new antibiotics.

13 Oct 2013

NIH selects Salk scientist for EUREKA grant

The National Institutes of Health has selected Axel Nimmerjahn for a highly competitive EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant. Dr. Nimmerjahn is an Assistant Professor in the Waitt Advanced Biophotonics Center and holds the Richard Allan Barry Developmental Chair.

13 Oct 2013

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick.

12 Oct 2013

UTHealth professor receives Oswald Avery Award for Early Achievement from IDSA

Cesar Arias, M.D., Ph.D., associate professor in the Division of Infectious Diseases at The University of Texas Health Science Center at Houston Medical School, was bestowed the Oswald Avery Award for Early Achievement from the Infectious Diseases Society of America.

12 Oct 2013

Yale Launches Collaboration With ARO, CRO Partners

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11 Oct 2013

New gene transfer strategy effective for achieving persistent immunotherapy to treat tumors

Cancer immunotherapy can successfully use the body's own immune system to kill tumor cells. But some current approaches to stimulate an antitumor immune response are short-lived, with limited clinical effectiveness. A new gene transfer strategy that introduces modified, immune-stimulating human stem cells is both feasible and effective for achieving persistent immunotherapy to treat leukemias and lymophomas, according to a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

11 Oct 2013

HSCI researchers discover on-off switch for gene expression

Harvard Stem Cell Institute researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before they are methylated.

11 Oct 2013

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

In an unprecedented move, the California Academy of Sciences today will induct two scientists from the Gladstone Institutes', President R. Sanders "Sandy" Williams, MD, and Investigator Katherine Pollard, PhD, as Academy Fellows, bestowing yet another honor on two of San Francisco's most esteemed scientists.

11 Oct 2013

TSRI scientists discover viable strategy for weight loss in people

Scientists at The Scripps Research Institute have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from the worm versions of the neurotransmitters serotonin and adrenaline, and there are reasons to suspect that it exists in a similar form in humans and other mammals.

11 Oct 2013

Evidence shows vaccination pilot campaigns highly successful during 2010 cholera epidemic

The deadly cholera epidemic that rocked earthquake-shattered Haiti in 2010, claiming 8,000 lives and counting, has rallied the public health community to seek water and sewer improvements that, combined with vaccination, could prevent some 89,000 future cholera infections.

11 Oct 2013

Finding highlights new ways of treating inflammation disorders

A team led by scientists at The Scripps Research Institute (TSRI) has identified key signaling proteins in the inflammation process that contribute to the development of inflammatory diseases such as rheumatoid arthritis, psoriasis, sepsis and inflammatory bowel diseases.

11 Oct 2013

J&J Innovation, Janssen, And Joslin Diabetes To Pump Up Exercise-Related Targets

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10 Oct 2013

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Constellation Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company in the field of epigenetics, today announced that it has been awarded a research grant in collaboration with the University of Pittsburgh School of Medicine from the Cystic Fibrosis Foundation to explore the potential use of BET bromodomain inhibitors for the control of inflammation in cystic fibrosis.

10 Oct 2013

$New report provides fracture prevention, management solutions for postmenopausal woman$

New report provides fracture prevention, management solutions for postmenopausal woman

According to a new report published today by the International Osteoporosis Foundation, women may expect to live longer but their quality of life will be seriously jeopardized if action to protect their bone health is not taken. Postmenopausal women are the most vulnerable to osteoporosis and fractures. Worldwide, an estimated 200 million women are affected by osteoporosis and around one in three women aged over 50 will suffer from a fracture due to the disease.

10 Oct 2013

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Scientists at The Scripps Research Institute (TSRI) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, the compounds boost a population of progenitor cells that can in turn repair MS-damaged nerve fibers.

10 Oct 2013

Neuroscientist receives CAREER grant to research on auditory processing and sound localization

Twenty years ago Khaleel A. Razak was an electronics engineering student focused on creating a telephone for hearing-impaired children in Chennai, India. Today he is a neuroscientist at the University of California, Riverside whose research on how the brain processes everyday sounds may lead to therapies for age-related hearing problems and Fragile X Syndrome.

10 Oct 2013

Study proposes novel treatment for narcolepsy

Lancet Neurology, a prestigious journal in its domain, publishes in its last issue, an article entitled "Pitolisant versus placebo and modafinil in patients with narcolepsy: a double-blind randomised trial" authored by Y. Dauvilliers and others from the HARMONY I study group which proposes a novel treatment for this orphan disease. It is accompanied by a Commentary entitled "A need for new treatments in narcolepsy".

10 Oct 2013

Mechanism preserving genome integrity help develop new therapies against DiGeorge syndrome

An international team of scientists-including researchers at GENYO, the Centre for Genomics and Oncological Research (Pfizer-University of Granada- Andalusian Regional Government)-has described a molecular mechanism that facilitates the defence of the human genome against "bombarding" by mobile DNA sequences.

10 Oct 2013

CHD Bioscience's lead product can help mitigate increasing threat of HAIs

According to a recent report issued by the Centers for Disease Control, every year more than two million people develop infections that are resistant to antibiotics. Specific healthcare-associated infections are classified as urgent threats and affect approximately 1.7 million people annually across the United States, leading to death in nearly 99,000 patients.

9 Oct 2013

Laboratory News and Research

Pregabalin drug can help reduce incidence of chronic pain following cardiac surgery

Researchers discover new approach to tackle global threat of antibiotic drug resistance

NIH selects Salk scientist for EUREKA grant

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

UTHealth professor receives Oswald Avery Award for Early Achievement from IDSA

Yale Launches Collaboration With ARO, CRO Partners

New gene transfer strategy effective for achieving persistent immunotherapy to treat tumors

HSCI researchers discover on-off switch for gene expression

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

TSRI scientists discover viable strategy for weight loss in people

Evidence shows vaccination pilot campaigns highly successful during 2010 cholera epidemic

Finding highlights new ways of treating inflammation disorders

J&J Innovation, Janssen, And Joslin Diabetes To Pump Up Exercise-Related Targets

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

New report provides fracture prevention, management solutions for postmenopausal woman

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Neuroscientist receives CAREER grant to research on auditory processing and sound localization

Study proposes novel treatment for narcolepsy

Mechanism preserving genome integrity help develop new therapies against DiGeorge syndrome

CHD Bioscience's lead product can help mitigate increasing threat of HAIs

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