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Latency reversing agent makes dormant HIV-infected cells vulnerable to clearance

The ability for HIV to hide in the body in a dormant state makes curing the 40 million people living with the virus a challenge. Researchers at the University of North Carolina at Chapel Hill have shown the drug Vorinostat reverses this latency, causing resting CD4 T-cells to express HIV.

1 Aug 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

Doctoral student works toward developing gluten-free children’s snack

Research to develop a gluten-free children's snack made of millet and quinoa has earned doctoral student Gabriela John Swamy the Gerber Endowment in Pediatric Nutrition Graduate Scholarship.

1 Aug 2017

Researchers streamline beta cell differentiation process to develop safer cell therapy for diabetes

More than 36 million people globally are affected by type 1 diabetes (T1D), a lifelong disorder where insulin producing cells are attacked and destroyed by the immune system resulting in deficient insulin production that requires daily blood glucose monitoring and administration of insulin.

1 Aug 2017

WPI researchers receive NIH grant to develop heart muscle patch using biopolymer microthreads

A research team at Worcester Polytechnic Institute has been awarded a $452,000 National Institutes of Health grant to bioengineer a patch to help cardiac muscle beat more strongly and efficiently after a heart attack.

31 Jul 2017

Penn researchers discover how DNA damage turns immune cells against cancer

Cancer is essentially a disease of the cell replication cycle. The goal of treating the disease is to permanently kill off the cells that replicate with abandon without any molecular brakes.

31 Jul 2017

Biomedical researcher wins $1.9 million federal grant to develop enhanced influenza vaccines

Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has renewed a four-year, $1.9 million federal grant to develop influenza vaccines that offer enhanced protection against a broad range of influenza virus strains.

31 Jul 2017

Simple blood test could help identify patients at greater risk of cardiac event after orthopedic surgery

A new study published today in the HSS Journal, the leading journal on musculoskeletal research, found the incidence of myocardial ischemia (defined by an elevated troponin level) after major orthopedic surgery in patients with cardiac risk factors is high, although the incidence of serious cardiac complications remains low.

31 Jul 2017

New substance restores brain function in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments.

28 Jul 2017

Structure of protein in salmon virus could inform strategies to treat flu in humans

The structure of a protein key to the survival and spread of a virus that affects salmon could inform strategies to treat the flu in humans, according to scientists at Rice University.

28 Jul 2017

Researchers compare bone-healing effects of three low-dose growth factors

Researchers compared the effects of three bone growth factors to bone morphogenetic protein 2 (BMP2) -- the most commonly used agent for repair of large bone defects, which is not without risks at the doses required--and showed significant bone-healing effects including the formation of new blood vessels at low doses relative to BMP2.

28 Jul 2017

Researchers unravel how acidic conditions favor protein misfolding in deadly diseases

Using an array of modern biochemical and structural biology techniques, researchers from Boston University School of Medicine have begun to unravel the mystery of how acidity influences a small protein called serum amyloid A (SAA).

28 Jul 2017

Estrogen uses certain cell type as 'mediator' for beneficial effects on the bone, research shows

The female sex hormone estrogen plays an important role in the structural stability of bones. To date, however, it had been unclear exactly which cells were involved in the hormone's protective function in preventing changes in bone density.

28 Jul 2017

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers at UT Southwestern Medical Center have uncovered an intriguing clue.

28 Jul 2017

Research: Many UK parents unaware about detrimental effects of spouted baby food on child’s development

Watch our video featuring health care experts giving their top tips and professional advice on how to marry the best convenience food with your baby’s developmental needs.

28 Jul 2017

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity.

27 Jul 2017

Protein C News and Research

Latency reversing agent makes dormant HIV-infected cells vulnerable to clearance

Expert highlights CRISPR’s applications, limitations, and ethical concerns

Doctoral student works toward developing gluten-free children’s snack

Researchers streamline beta cell differentiation process to develop safer cell therapy for diabetes

WPI researchers receive NIH grant to develop heart muscle patch using biopolymer microthreads

Penn researchers discover how DNA damage turns immune cells against cancer

Biomedical researcher wins $1.9 million federal grant to develop enhanced influenza vaccines

Simple blood test could help identify patients at greater risk of cardiac event after orthopedic surgery

New substance restores brain function in Alzheimer's animal model

Structure of protein in salmon virus could inform strategies to treat flu in humans

Researchers compare bone-healing effects of three low-dose growth factors

Researchers unravel how acidic conditions favor protein misfolding in deadly diseases

Estrogen uses certain cell type as 'mediator' for beneficial effects on the bone, research shows

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Research: Many UK parents unaware about detrimental effects of spouted baby food on child’s development

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

Case Western Reserve University professor awarded $150,000 for pediatric cancer research

Gene editing technology shines light on rare dyskeratosis congenita

Immune system may wage a battle in Parkinson’s disease

UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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