Life Expectancy News and Research

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Life expectancy is the expected (in the statistical sense) number of years of life remaining at a given age. It is denoted by e''x'', which means the average number of subsequent years of life for someone now aged ''x'', according to a particular mortality experience.

Research finding could yield new ideas for treating symptoms of motor neurone disease

Scientists in Aberdeen have discovered a mechanism that muscles use to regulate the nerves which control them. They believe their finding could yield new ideas for treating symptoms of motor neurone disease - a progressive and incurable neurodegenerative condition that leads to muscle weakness and wasting - and other neuromuscular conditions.

13 Jul 2010

Behavioral change programs help lower risk for cardiovascular diseases: Scientific statement

Combining counseling, extended follow-up with a healthcare provider and self-monitoring of diet and exercise is the most effective way to help patients embrace lifestyle changes that can lower their risk for heart and blood vessel (cardiovascular) diseases, according to a scientific statement published in Circulation: Journal of the American Heart Association.

13 Jul 2010

Biogen Idec, Swedish Orphan Biovitrum present results from rFIXFc Phase 1/2a study in hemophilia B

Biogen Idec and Swedish Orphan Biovitrum AB today announced results from a Phase 1/2a open-label, dose-escalation, safety and pharmacokinetic study of the companies' long-lasting, fully-recombinant factor IX Fc fusion protein (rFIXFc) in hemophilia B patients. The data, which were presented at the World Federation of Hemophilia Congress in Buenos Aires, Argentina, on July 11, 2010, showed that rFIXFc was well tolerated and demonstrated an approximately three-fold increase in half-life compared to historical data for existing therapies.

12 Jul 2010

Biogen Idec, Swedish Orphan Biovitrum announce advancement of rFVIIIFc into registrational study

Biogen Idec and Swedish Orphan Biovitrum today announced that they plan to advance the companies' long-lasting, fully-recombinant factor VIII Fc fusion protein (rFVIIIFc) into a registrational clinical trial in people with hemophilia A. The decision to advance the program is based on promising data from a Phase 1/2a open-label, cross-over, multi-center, dose-escalation study that evaluated the safety and pharmacokinetics of an intravenous injection of rFVIIIFc in 16 previously-treated patients with severe hemophilia A.

12 Jul 2010

Study examines impact of universal HIV testing, immediate ART program in Washington, DC

Implementing a program of universal HIV testing and immediate antiretroviral treatment for infected individuals could have a major impact on the HIV/AIDS epidemic in Washington, DC, but a new study finds that it would not halt the epidemic, something that a previous report had projected. In a paper that will appear in the August 15 issue of Clinical Infectious Diseases and has been released online, researchers find that the so-called "test-and-treat" strategy could reduce new HIV infections by 15 percent over the next five years while conferring large survival benefits to HIV-infected patients.

12 Jul 2010

Men with higher baseline PSA value more likely to die from prostate cancer, say researchers

Men who have a baseline PSA value of 10 or higher the first time they are tested are up to 11 times more likely to die from prostate cancer than are men with lower initial values, according to Duke University Medical Center researchers.

9 Jul 2010

First patient enrolled in Boston Scientific's MultiSENSE clinical trial

Boston Scientific Corporation today announced enrollment of the first patient in its MultiSENSE clinical trial. The trial is designed to evaluate multiple physiologic sensors in the Company's COGNIS cardiac resynchronization therapy defibrillators. Boston Scientific plans to use the trial data to help develop a clinical alert that identifies the early onset of worsening heart failure.

8 Jul 2010

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today it has initiated dosing in a Phase I human clinical study with ALN-TTR01. The study is aimed at evaluating the safety and tolerability of ALN-TTR01 in patients with transthyretin -mediated amyloidosis, and is also designed to provide preliminary data on human proof of concept based on measurements of TTR serum levels.

7 Jul 2010

Elsevier, SIOG launch Journal of Geriatric Oncology

Elsevier, the world-leading publisher of scientific, technical and medical information products and services, and the International Society of Geriatric Oncology (SIOG) announced today the launch of the Journal of Geriatric Oncology. The journal is focused on advancing research in the pathogenesis, biology, treatment, and survivorship issues of older adults with cancer. It covers all aspects of geriatric oncology, from basic scientific research through to clinical research, as well as research that is relevant to education and policy development.

6 Jul 2010

Women have longer life expectancy, but with prevalence of disability in old age

Although women have a longer life expectancy, they experience a much greater prevalence of disability in old age than men do. This is the main conclusion of the study published in the latest issue of the Journal of Women's Health.

3 Jul 2010

Research Roundup: 'Pay-for-performance' unintended effects; Lessons from Mass.; End of life treatment

Archives of Internal Medicine: The Quality Of Care Provided To Hospitalized Patients At The End of Life - In this study, researchers used a set of quality indicators to assess the end-of-life care and pain management received by 496 patients who died three or more days after admission at the University of California-Los Angeles Medical Center. The authors found "pain assessments (94%) and treatments for pain (95%) and dyspnea [breathing problems] (87%) were performed with fidelity."

3 Jul 2010

LPD study unveils similarities, differences among Life Expectancy Underwriters

A study just released by Life Policy Dynamics (LPD) revealed some significant differences among Life Expectancy Underwriters, as well as some similarities.

2 Jul 2010

Malnutrition during childhood diminishes brain function in late life

Malnutrition early in life appears to diminish brain function in older adulthood, according to a study led by a Michigan State University researcher that has implications for many poor, developing nations.

2 Jul 2010

Behavioral intervention program can reduce incidence of HIV, STIs among female sex workers: Researchers

A team of researchers from the University of California San Diego and Mexico has found that even a modest behavioral intervention program averaging just 35 minutes can measurably reduce the incidence of HIV and sexually transmitted infections among female sex workers in the U.S.-Mexico border region - and that the program succeeds at comparatively little expense.

1 Jul 2010

Alnylam receives Portuguese, Swedish, British approvals to initiate ALN-TTR01 Phase I study in ATTR

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that its applications for ALN-TTR01 have been given clearance by Portuguese, Swedish, and British regulatory authorities to begin clinical testing. The trial will begin enrolling patients shortly in a blinded, randomized, placebo-controlled, multicenter Phase I study.

29 Jun 2010

Young breast cancer patients more likely to discontinue hormone therapy

A new study of nearly 8,800 women with early-stage breast cancer found that fewer than half - approximately 49 percent - completed their full regimen of hormone therapy according to the prescribed schedule.

29 Jun 2010

US lags in health system performance

Despite having the most expensive health care system, the United States ranks last overall compared to six other industrialized countries-Australia, Canada, Germany, the Netherlands, New Zealand, and the United Kingdom-on measures of health system performance in five areas: quality, efficiency, access to care, equity and the ability to lead long, healthy, productive lives, according to a new Commonwealth Fund report.

23 Jun 2010

Active surveillance sufficient for patients with low-risk prostate cancer

Active surveillance or watchful waiting might be sufficient treatment for patients with prostate cancer that has a low risk of progression, according to a new study published online June 18 in The Journal of the National Cancer Institute.

19 Jun 2010

Also in Global Health News: Clinton to Haiti; Global Fund suspends Zambian aid; Ugandan health workers; MDG summit; Rwandan health insurance; HIV drugs in Kenya

Reuters reports that former President Bill Clinton will return to Haiti to "jump-start" the country's post-earthquake reconstruction. Clinton will head the first meeting of Haiti's reconstruction commission, "part of a sorely needed effort to better coordinate international aid efforts, [Prime Minister Jean-Max] Bellerive said." Bellerive hopes the meeting will "establish clear-cut guidelines" for distributing more than $5 billion in aid from 140 countries following the Jan. 12 earthquake (Brown, 6/16).

16 Jun 2010

NBC's TODAY Show to focus on PF in an interview with a patient from California

The Coalition for Pulmonary Fibrosis announced today one of the first major national media coverage opportunities for the CPF and Pulmonary Fibrosis. NBC's TODAY Show will focus on the disease in an interview with California patient Bob O'Rourke, who suffers from the disease and will die from it unless he receives a lung transplant in time.

15 Jun 2010

Life Expectancy News and Research

Further Reading

Research finding could yield new ideas for treating symptoms of motor neurone disease

Behavioral change programs help lower risk for cardiovascular diseases: Scientific statement

Biogen Idec, Swedish Orphan Biovitrum present results from rFIXFc Phase 1/2a study in hemophilia B

Biogen Idec, Swedish Orphan Biovitrum announce advancement of rFVIIIFc into registrational study

Study examines impact of universal HIV testing, immediate ART program in Washington, DC

Men with higher baseline PSA value more likely to die from prostate cancer, say researchers

First patient enrolled in Boston Scientific's MultiSENSE clinical trial

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Elsevier, SIOG launch Journal of Geriatric Oncology

Women have longer life expectancy, but with prevalence of disability in old age

Research Roundup: 'Pay-for-performance' unintended effects; Lessons from Mass.; End of life treatment

LPD study unveils similarities, differences among Life Expectancy Underwriters

Malnutrition during childhood diminishes brain function in late life

Behavioral intervention program can reduce incidence of HIV, STIs among female sex workers: Researchers

Alnylam receives Portuguese, Swedish, British approvals to initiate ALN-TTR01 Phase I study in ATTR

Young breast cancer patients more likely to discontinue hormone therapy

US lags in health system performance

Active surveillance sufficient for patients with low-risk prostate cancer

Also in Global Health News: Clinton to Haiti; Global Fund suspends Zambian aid; Ugandan health workers; MDG summit; Rwandan health insurance; HIV drugs in Kenya

NBC's TODAY Show to focus on PF in an interview with a patient from California

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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