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Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell.

30 Aug 2013

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

Researchers at Lund University have unexpectedly discovered that an old cancer drug can be used to prevent rejection of transplanted tissue. The researchers now have high hopes that their discovery could lead to new treatments for both transplant patients and patients with autoimmune diseases.

29 Aug 2013

JHI signs agreement with HMV to enhance clinical care, patient safety and nursing education

Enhancements in clinical care and patient safety, medical research and nursing initiatives are at the core of a new affiliation agreement signed on Aug. 27 by Johns Hopkins Medicine International, Baltimore, USA, and Hospital Moinhos de Vento of Porto Alegre, one of Brazil’s leaders in health care delivery and innovation.

28 Aug 2013

Researchers suggest new therapeutic target for brain tumor

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas — the most common form of brain tumor — suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Researchers find specific protein in nearly all high-grade meningiomas

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas -- the most common form of brain tumor -- suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Ability to draw spontaneously may be preserved in brains of artists even after vascular dementia

The ability to draw spontaneously as well as from memory may be preserved in the brains of artists long after the deleterious effects of vascular dementia have diminished their capacity to complete simple, everyday tasks, according to a new study by physicians at St. Michael's Hospital.

26 Aug 2013

Scientists Shed New Light On Malignant Pancreatic Cancer

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23 Aug 2013

Scientists identify molecular mechanism that contributes to pancreatic cancer

New research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) and Baylor College of Medicine could aid efforts to diagnose and treat one of the most lethal and hard-to-treat types of cancer.

23 Aug 2013

Chronic traumatic encephalopathy may affect people's thinking, memory, behavior and mood

New research suggests that chronic traumatic encephalopathy, a brain disease associated with repeat brain trauma including concussions in athletes, may affect people in two major ways: initially affecting behavior or mood or initially affecting memory and thinking abilities.

22 Aug 2013

Study: Mother's mitochondrial DNA seems to influence our own aging

As we age, our cells change and become damaged. Now, researchers at Karolinska Institutet and the Max Planck Institute for Biology of Aging have shown that aging is determined not only by the accumulation of changes during our lifetime but also by the genes we acquire from our mothers.

22 Aug 2013

NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

House Research Institute (HRI) and Children's Hospital Los Angeles Children's Hospital) announced today final approval of grant funding by the National Institutes of Health (NIH) National Institute on Deafness and Communications Disorders (NIDCD) for a major five-year, FDA-approved clinical trial of the auditory brainstem implant (ABI) in children.

21 Aug 2013

Study shows continuous CSF drainage is associated with complications in patients with SAH

Researchers at Duke University conducted a randomized clinical trial in patients with subarachnoid hemorrhage (SAH). In this study, the researchers compared two approaches to intracranial pressure management-continuous and intermittent drainage of cerebrospinal fluid (CSF)-and outcomes associated with those methods, focusing specifically on the incidence of cerebral vasospasm.

21 Aug 2013

Copper enhances progression of Alzheimer's disease

Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer's disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain. That is the conclusion of a study appearing today in the journal Proceedings of the National Academy of Sciences.

20 Aug 2013

Study: Cell cycle-related genes play important role in formation of neural tube defects

In the field of developmental neurobiology, accurate and ordered regulation of the cell cycle and apoptosis are crucial factors contributing to the normal formation of the neural tube.

16 Aug 2013

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

X-linked methyl-CpG binding protein 2 plays important role in the regulation of neuronal development, proliferation and maturation, and synaptic regeneration and apoptosis.

13 Aug 2013

Researchers identify clear genetic risk factors in patients with severe epilepsy

Neurologists and epilepsy researchers from NYU Langone Medical Center were among scientists who have 329 random genetic mutations associated with two of the most severe forms of epilepsy, according to a paper published today in Nature.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

There are two traits closely associated with the development of alcohol use disorders (AUDs). One is a lower subjective intoxication response, also known as a low level of response to alcohol.

12 Aug 2013

Neurosurgery News and Research

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

JHI signs agreement with HMV to enhance clinical care, patient safety and nursing education

Researchers suggest new therapeutic target for brain tumor

Researchers find specific protein in nearly all high-grade meningiomas

Ability to draw spontaneously may be preserved in brains of artists even after vascular dementia

Scientists Shed New Light On Malignant Pancreatic Cancer

Scientists identify molecular mechanism that contributes to pancreatic cancer

Chronic traumatic encephalopathy may affect people's thinking, memory, behavior and mood

Study: Mother's mitochondrial DNA seems to influence our own aging

NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

Study shows continuous CSF drainage is associated with complications in patients with SAH

Copper enhances progression of Alzheimer's disease

Study: Cell cycle-related genes play important role in formation of neural tube defects

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

Researchers identify clear genetic risk factors in patients with severe epilepsy

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Researchers explore potential of neural stem cells to repair brain damage

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

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