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NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

House Research Institute (HRI) and Children's Hospital Los Angeles Children's Hospital) announced today final approval of grant funding by the National Institutes of Health (NIH) National Institute on Deafness and Communications Disorders (NIDCD) for a major five-year, FDA-approved clinical trial of the auditory brainstem implant (ABI) in children.

21 Aug 2013

Study shows continuous CSF drainage is associated with complications in patients with SAH

Researchers at Duke University conducted a randomized clinical trial in patients with subarachnoid hemorrhage (SAH). In this study, the researchers compared two approaches to intracranial pressure management-continuous and intermittent drainage of cerebrospinal fluid (CSF)-and outcomes associated with those methods, focusing specifically on the incidence of cerebral vasospasm.

21 Aug 2013

Copper enhances progression of Alzheimer's disease

Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer's disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain. That is the conclusion of a study appearing today in the journal Proceedings of the National Academy of Sciences.

20 Aug 2013

Study: Cell cycle-related genes play important role in formation of neural tube defects

In the field of developmental neurobiology, accurate and ordered regulation of the cell cycle and apoptosis are crucial factors contributing to the normal formation of the neural tube.

16 Aug 2013

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

X-linked methyl-CpG binding protein 2 plays important role in the regulation of neuronal development, proliferation and maturation, and synaptic regeneration and apoptosis.

13 Aug 2013

Researchers identify clear genetic risk factors in patients with severe epilepsy

Neurologists and epilepsy researchers from NYU Langone Medical Center were among scientists who have 329 random genetic mutations associated with two of the most severe forms of epilepsy, according to a paper published today in Nature.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

There are two traits closely associated with the development of alcohol use disorders (AUDs). One is a lower subjective intoxication response, also known as a low level of response to alcohol.

12 Aug 2013

Complex and messy ethical, social and cultural issues often left on table

Resolving complex ethical, social and cultural issues in the early stage of a global health research project or clinical trial can improve the impact and quality of that research, a new report says.

12 Aug 2013

Study reveals gray matter atrophy in multiple sclerosis correlated with emotional decline

In multiple sclerosis, gray matter atrophy is extensive, and cognitive deficits and mood disorders are frequently encountered. It has been conjectured that focal atrophy is associated with emotional decline.

12 Aug 2013

Endovascular Therapy still "reasonable" option for patients with acute stroke

Despite recent discouraging results, endovascular treatment is still a "reasonable" treatment option for selected patients with acute stroke, according to a commentary in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

8 Aug 2013

Ohio State's Wexner Medical Center neurosurgeons implant MRI-safe spinal cord stimulator for pain

Neurosurgeons at The Ohio State University Wexner Medical Center are among the first in the United States to successfully implant an MRI-safe spinal cord stimulator to help patients suffering from chronic back or limb pain.

From Medtronic 7 Aug 2013

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center have successfully combined cellular therapy and gene therapy in a mouse-model system to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.

7 Aug 2013

Researchers identify new type of cell in brain that helps people to keep track of their relative location

Using direct human brain recordings, a research team from Drexel University, the University of Pennsylvania, UCLA and Thomas Jefferson University has identified a new type of cell in the brain that helps people to keep track of their relative location while navigating an unfamiliar environment.

6 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

Intrinsic Therapeutics enrolls 400th patient in randomized clinical trial to evaluate effectiveness of Barricaid prosthesis

Intrinsic Therapeutics today announced the enrollment of the 400th patient in a level 1, prospective, randomized, multi-center clinical trial evaluating the effectiveness of its Barricaid Prosthesis in improving outcomes for lumbar discectomy patients suffering from sciatica.

1 Aug 2013

Combination of tPA with infusion of antiplatelet drug dissolves blood clots safely

The combination of the clot-busting drug tPA with an infusion of the antiplatelet drug eptifibatide dissolves blood clots safely and more quickly than tPA alone, a study led by University of Cincinnati (UC) researchers has found.

31 Jul 2013

Less contact during practice can reduce exposure to head injuries for young football players

Less contact during practice could mean a lot less exposure to head injuries for young football players, according to researchers at Wake Forest Baptist Medical Center and Virginia Tech.

30 Jul 2013

Neurosurgery News and Research

NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

Study shows continuous CSF drainage is associated with complications in patients with SAH

Copper enhances progression of Alzheimer's disease

Study: Cell cycle-related genes play important role in formation of neural tube defects

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

Researchers identify clear genetic risk factors in patients with severe epilepsy

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Researchers explore potential of neural stem cells to repair brain damage

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

Complex and messy ethical, social and cultural issues often left on table

Study reveals gray matter atrophy in multiple sclerosis correlated with emotional decline

Endovascular Therapy still "reasonable" option for patients with acute stroke

Ohio State's Wexner Medical Center neurosurgeons implant MRI-safe spinal cord stimulator for pain

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

Researchers identify new type of cell in brain that helps people to keep track of their relative location

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Intrinsic Therapeutics enrolls 400th patient in randomized clinical trial to evaluate effectiveness of Barricaid prosthesis

Combination of tPA with infusion of antiplatelet drug dissolves blood clots safely

Less contact during practice can reduce exposure to head injuries for young football players

Neuroscience - Third Edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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