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Deletion of a protein improves ability to fight bacteria in mice with CGD

Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes of Health study. CGD, a genetic disorder also found in people, is marked by recurrent, life-threatening infections. The study's findings appear online in The Journal of Clinical Investigation.

2 Aug 2013

Breath analysis: Noninvasive way to quickly determine severity of bacterial infections

Breath analysis may prove to be an accurate, noninvasive way to quickly determine the severity of bacterial and other infections, according to a UC Irvine study appearing online today in the open-access journal PLOS ONE.

2 Aug 2013

New report shows that access to clean water and soap may boost growth in children

Improving water quality and hygiene practices may improve the growth of children, according to a new report. The Cochrane review – authored by the London School of Hygiene & Tropical Medicine and WaterAid – found evidence of small but significant improvements in growth of children under the age of five who have access to clean water and soap.

1 Aug 2013

UNICEF: Breastfeeding is the most effective life-saver for children

During World Breastfeeding Week starting today, UNICEF is focusing on breastfeeding as the most effective and inexpensive way of saving a child’s life. But with less than half of all children under six months benefitting from exclusive breastfeeding, strong leadership in promoting the practice is essential.

1 Aug 2013

Boehringer Ingelheim, Lilly initiate linagliptin clinical trial in adults with Type 2 Diabetes

Boehringer Ingelheim and Eli Lilly and Company today announced enrollment of the first patient into a cardiovascular and renal outcomes trial for linagliptin (Trajenta).

1 Aug 2013

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cancer immunotherapy aims to recruit a patient’s immune system to recognize cancer as foreign and dangerous and to remove it from the body, as it would an infection.

1 Aug 2013

Intrinsic Therapeutics enrolls 400th patient in randomized clinical trial to evaluate effectiveness of Barricaid prosthesis

Intrinsic Therapeutics today announced the enrollment of the 400th patient in a level 1, prospective, randomized, multi-center clinical trial evaluating the effectiveness of its Barricaid Prosthesis in improving outcomes for lumbar discectomy patients suffering from sciatica.

1 Aug 2013

Genetic testing launched to identify genetic risk for kidney disease in patients with hypertension

The Icahn School of Medicine at Mount Sinai is partnering with the Institute for Family Health to launch the first-ever genetic testing program in the primary care setting to identify genetic risk for kidney disease in patients with hypertension.

1 Aug 2013

Researchers contribute to key step in finding cure for prion-folding diseases in humans

The work of University of Alberta researchers and their teams has contributed to an important next step in finding a cure for deadly prion-folding diseases in humans and animals.

1 Aug 2013

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Administering the drug rituximab once weekly for one month provides the same benefits as 18 months of daily immunosuppressive therapy in people with severe forms of vasculitis, or inflammation of the blood vessels, a study has found.

1 Aug 2013

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Scientists seeking to harness the healing power of a miniscule signaling molecule that plays a critical role in certain acute and chronic diseases have been awarded a Program Project Grant (PPG) of nearly $10 million by the National Heart, Lung and Blood Institute of the National Institutes of Health.

1 Aug 2013

Novel protein could lead to development of new drugs to treat variety of cancers

In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting.

1 Aug 2013

Article suggests socially-based approach for treating Alzheimer's, other cognitive disorders

In the article "The Challenges of Cognitive Aging: Integrating Approaches from Neuroscience to Intergenerational Relationships," published in the Journal of Intergenerational Relationships, author Peter Whitehouse suggests a more socially-based approach to treating Alzheimer's and other cognitive disorders.

31 Jul 2013

MiMedx Group Q2 revenue increases more than 175%

MiMedx Group, Inc., an integrated developer, manufacturer and marketer of patent protected regenerative biomaterials and bioimplants processed from human amniotic membrane, announced today its results for the quarter ended June 30, 2013.

31 Jul 2013

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Pain is defined by the sufferer’s experience. Pain may be severe because it is intense, frequent or sustained, and because it is distressing. The severity of pain is not simply due to what is going on in the joint, but is also affected by how the body processes the pain signals, and the context in which it is experienced.

31 Jul 2013

Taxing on sugary beverages may not reduce obesity rates, say researchers

Taxing sugary beverages may help reduce calories, but the health benefits may be offset as consumers substitute other unhealthy foods, according to a joint study by researchers at RTI International, Duke University, and the U.S. Department of Agriculture.

31 Jul 2013

New treatment options give hope to people with psoriasis

Psoriasis expert and researcher Steve Feldman, M.D., says there are many new treatment options giving hope to the millions of people who suffer from the chronic skin condition.

31 Jul 2013

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center today announced they received a $16 million grant from the National Institutes of Health to investigate the impact of HIV and AIDS on women.

31 Jul 2013

State highlights: Mandatory treatment for mental illness working in NY, study finds; Ore. regulators lower insurance rates $69M

A year ago, Montana opened the nation's first clinic for free primary health care services to its state government employees. The Helena, Mont., clinic was pitched as a way to improve overall employee health, but the idea has faced its fair share of political opposition. A year later, the state says the clinic is already saving money (Boyce, 7/30).

31 Jul 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Chronic News and Research

Deletion of a protein improves ability to fight bacteria in mice with CGD

Breath analysis: Noninvasive way to quickly determine severity of bacterial infections

New report shows that access to clean water and soap may boost growth in children

UNICEF: Breastfeeding is the most effective life-saver for children

Boehringer Ingelheim, Lilly initiate linagliptin clinical trial in adults with Type 2 Diabetes

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Intrinsic Therapeutics enrolls 400th patient in randomized clinical trial to evaluate effectiveness of Barricaid prosthesis

Genetic testing launched to identify genetic risk for kidney disease in patients with hypertension

Researchers contribute to key step in finding cure for prion-folding diseases in humans

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Novel protein could lead to development of new drugs to treat variety of cancers

Article suggests socially-based approach for treating Alzheimer's, other cognitive disorders

MiMedx Group Q2 revenue increases more than 175%

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Taxing on sugary beverages may not reduce obesity rates, say researchers

New treatment options give hope to people with psoriasis

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

State highlights: Mandatory treatment for mental illness working in NY, study finds; Ore. regulators lower insurance rates $69M

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

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