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Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus.

18 May 2017

KU Leuven researchers identify vital role of TET1 protein in earliest stages of embryonic development

In the earliest stages of embryonic development, a protein known as TET1 may be the factor that tips the balance toward health or disease.

18 May 2017

Research paves way for safer and more effective drugs to treat type 2 diabetes

Research led by the University of Adelaide is paving the way for safer and more effective drugs to treat type 2 diabetes, reducing side effects and the need for insulin injections.

18 May 2017

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

The U.S. Food and Drug Administration today expanded the approved use of Kalydeco (ivacaftor) for treating cystic fibrosis.

18 May 2017

Research findings may provide answers for infertility in older women

Findings from new research led by the Monash Biomedicine Discovery Institute and University College London may finally resolve, and potentially provide answers, as to why older women have higher incidences of miscarriage and have babies with chromosomal abnormalities.

18 May 2017

Scientists reveal new control mechanism for gene that causes Opitz syndrome

Opitz G/BBB (Opitz) syndrome is a hereditary disorder that affects people in different ways, causing malformations in medial (midline) organs and structures, intellectual disability and developmental disorders.

18 May 2017

Newly identified biomarkers could help predict cognitive deficits in Parkinson's disease patients

New biomarkers identified by a research team in the Perelman School of Medicine at the University of Pennsylvania could help predict which Parkinson's disease patients will suffer significant cognitive deficits within the first three years of their diagnosis.

18 May 2017

$Innovative technique could replace bone grafts to repair severe limb fractures$

Innovative technique could replace bone grafts to repair severe limb fractures

A Cedars-Sinai-led team of investigators has successfully repaired severe limb fractures in laboratory animals with an innovative technique that cues bone to regrow its own tissue.

17 May 2017

Microbes can manipulate molecular machinery of host cells to influence health

All animals -- from sea sponges to modern-day humans -- evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology as our own tissues and organs.

17 May 2017

Researchers identify new drug target for two common types of myeloid leukemia

University of Georgia researchers, with colleagues from the University of Tokyo, have identified a new drug target for the two most common types of myeloid leukemia, including a way to turn back the most aggressive form of the disease.

17 May 2017

Experimental gene therapy proven safe for preserving vision of people with AMD

In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it may be effective in preserving the vision of people with wet age-related macular degeneration.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Researchers from the University of Eastern Finland have discovered a likely cause for visual impairment and eventual loss of vision in the Finnish variant of Neuronal Ceroid Lipofuscinosis.

17 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

Researchers measure spread of tau protein in the brains of Alzheimer’s patients

In a new study presented in Molecular Psychiatry, researchers at Karolinska Institutet have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer's disease.

16 May 2017

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

Mayo Clinic study provides information on survival and death of patients with synucleinopathies

Faced with a serious disease, patients want to know the answer to a difficult question: "How long will I live?"

16 May 2017

Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

Protein C News and Research

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

KU Leuven researchers identify vital role of TET1 protein in earliest stages of embryonic development

Research paves way for safer and more effective drugs to treat type 2 diabetes

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

Research findings may provide answers for infertility in older women

Scientists reveal new control mechanism for gene that causes Opitz syndrome

Newly identified biomarkers could help predict cognitive deficits in Parkinson's disease patients

Innovative technique could replace bone grafts to repair severe limb fractures

Microbes can manipulate molecular machinery of host cells to influence health

Researchers identify new drug target for two common types of myeloid leukemia

Experimental gene therapy proven safe for preserving vision of people with AMD

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Researchers identify many dangerous strains of TB pathogens

Scientists unravel mystery of T cell signaling process vital to immune response

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Researchers measure spread of tau protein in the brains of Alzheimer’s patients

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Mayo Clinic study provides information on survival and death of patients with synucleinopathies

Study unravels new clues to cause and treatment of spinal muscular atrophy

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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