Laboratory News and Research

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Accumulation of plaques in brain may serve as powerful biomarker for early detection of cognitive decline

The trajectory of amyloid plaque buildup-clumps of abnormal proteins in the brain linked to Alzheimer's disease-may serve as a more powerful biomarker for early detection of cognitive decline rather than using the total amount to gauge risk, researchers from Penn Medicine's Department of Radiology suggest in a new study published online July 15 in Neurobiology of Aging.

16 Jul 2013

Researchers identify genes that allow animal hepatitis E virus strains to infect humans

X.J. Meng, a University Distinguished Professor at Virginia Tech and a virologist at the Virginia-Maryland Regional College of Veterinary Medicine, has received a four-year, nearly $1.6 million grant from the National Institutes of Health to better understand the genetic elements that allow hepatitis E virus to transfer from animals to people.

16 Jul 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time.

16 Jul 2013

Use of electronic health records can reduce costs of outpatient care, says study

Use of electronic health records can reduce the costs of outpatient care by roughly 3 percent, compared to relying on traditional paper records.

16 Jul 2013

Specific types of intestinal bacteria are major contributors to lymphoma

Researchers from UCLA's Jonsson Comprehensive Cancer Center (JCCC) have discovered that specific types of bacteria that live in the gut are major contributors to lymphoma, a cancer of the white blood cells that are part of the human immune system.

16 Jul 2013

Fixed-ratio transfusion protocol in trauma patients is feasible, but wastes blood plasma

The use of a 1:1:1 blood transfusion protocol in patients with severe trauma is feasible in hospitals, although it is associated with higher waste of plasma, according to a randomized trial published in CMAJ (Canadian Medical Association Journal).

16 Jul 2013

Obese fathers may pass their obesity to children and grandchildren

New research from the University of Adelaide shows that the sperm of obese fathers could increase the risk of both their children and their grandchildren to inherit obesity.

16 Jul 2013

Cranberry consumption may prevent chronic infections

Consuming cranberry products has been anecdotally associated with prevention of urinary tract infections (UTIs) for over 100 years. But is this popular belief a myth, or scientific fact?

16 Jul 2013

Study provides first novel insights into neural origins of hot flashes in menopausal women

A new study from neuroscientists at the Wayne State University School of Medicine provides the first novel insights into the neural origins of hot flashes in menopausal women in years.

16 Jul 2013

Exalenz Bioscience launches BreathID Hp to test and treat H. pylori

Exalenz Bioscience, developer of advanced diagnostic systems that use a patient's breath to detect and help manage gastrointestinal and liver conditions, announced today the global launch of the BreathID Hp, a next generation device in the company's BreathID product line.

15 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

TSRI scientists design drug candidate that increases exercise endurance in animal models

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models.

15 Jul 2013

Scientists discover new details of biochemical interactions necessary for cell division

Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target.

15 Jul 2013

Scientists uncover mechanism that controls cell death processes

Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.

15 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Study provides new relationship clue between motivational deficits, functional impairment

Many people with schizophrenia have marked problems with motivation, failing to initiate and persist in goal-directed behavior. These negative symptoms of schizophrenia can be disabling and prevent individuals from realizing their potential.

12 Jul 2013

Research: Sharp edged graphene sheets can easily pierce cell membranes

Researchers from Brown University have shown how tiny graphene microsheets - ultra-thin materials with a number of commercial applications - could be big trouble for human cells.

12 Jul 2013

New noninvasive technique for tracking stem cells after transplantation

A new, noninvasive technique for tracking stem cells after transplantation - developed by a cross-disciplinary team of radiologists, chemists, statisticians and materials scientists at the Stanford University School of Medicine - could help surgeons determine whether a procedure to repair injured or worn-out knees is successful.

12 Jul 2013

Researchers develop new cry analyzer to look for clues about baby's health

To parents, a baby's cry is a signal of hunger, pain, or discomfort. But to scientists, subtle acoustic features of a cry, many of them imperceptible to the human ear, can hold important information about a baby's health.

12 Jul 2013

Patients suffering from severe Charcot-Marie-Tooth disease can benefit from reconstructive surgery

For patients suffering from Charcot-Marie-Tooth disease - a surprisingly common neurological disorder that can cause the feet to become weak and contorted - surgery is considered a last resort. But for patients like Elissa Williams and her brother Kyle, surgery can bring an end to crippling pain and lead to active lives with feet facing forward and balanced on the ground.

12 Jul 2013

Laboratory News and Research

Accumulation of plaques in brain may serve as powerful biomarker for early detection of cognitive decline

Researchers identify genes that allow animal hepatitis E virus strains to infect humans

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Use of electronic health records can reduce costs of outpatient care, says study

Specific types of intestinal bacteria are major contributors to lymphoma

Fixed-ratio transfusion protocol in trauma patients is feasible, but wastes blood plasma

Obese fathers may pass their obesity to children and grandchildren

Cranberry consumption may prevent chronic infections

Study provides first novel insights into neural origins of hot flashes in menopausal women

Exalenz Bioscience launches BreathID Hp to test and treat H. pylori

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

TSRI scientists design drug candidate that increases exercise endurance in animal models

Scientists discover new details of biochemical interactions necessary for cell division

Scientists uncover mechanism that controls cell death processes

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

Study provides new relationship clue between motivational deficits, functional impairment

Research: Sharp edged graphene sheets can easily pierce cell membranes

New noninvasive technique for tracking stem cells after transplantation

Researchers develop new cry analyzer to look for clues about baby's health

Patients suffering from severe Charcot-Marie-Tooth disease can benefit from reconstructive surgery

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