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Study finds no link between gluten intake and heart disease risk in people without celiac disease

A study of more than 100,000 men and women revealed that dietary gluten is not associated with heart disease risk in people without celiac disease. The findings also suggest that limiting whole grains as part of a low-gluten diet may increase the risk of heart disease in people who do not have celiac disease.

3 May 2017

TSRI study reveals clues to where tumor metastases are born

Scientists at The Scripps Research Institute have discovered why some cancers may reoccur after years in remission.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

Discovery of protein that causes liver disease brings hope for new treatments

In a world-first discovery, scientists at Sydney’s Westmead Institute for Medical Research have identified a protein that causes liver fibrosis (scarring), paving the way for new treatments for liver disease to be developed.

3 May 2017

Researchers use simple blood tests to improve treatment for resistant hypertension in Africa

Using two simple blood tests, Western University researchers were able to drastically improve treatment for resistant hypertension across three sites in Nigeria, Kenya and South Africa.

2 May 2017

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

The formation of a human embryo starts with the fertilization of the oocyte by the sperm cell. This yields the zygote, the primordial cell that carries one copy each of the maternal and paternal genomes.

2 May 2017

Researchers uncover new potential target for treating spinal muscular atrophy

Though spinal muscular atrophy in its most severe form remains incurable and fatal in early childhood, researchers are sustaining a multipronged counterattack for patients and their families. The first treatment for the disease gained U.S. market approval in December.

2 May 2017

Researchers uncover molecule that may explain smoking-CHD connection

Cigarette smoking accounts for about one-fifth of cases of coronary heart disease, one of the leading causes of death worldwide, but precisely how smoking leads to CHD has long been unclear.

2 May 2017

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

Surgery and radiation remove, kill, or damage cancer cells in a certain area. But chemotherapy -- which uses medicines or drugs to treat cancer -- can work throughout the whole body, killing cancer cells that have spread far from the original tumor.

2 May 2017

Combination therapy may be effective option for treating some women with ovarian cancer

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer -- the most common subtype of ovarian cancer -- after standard treatment with the chemotherapy drug carboplatin.

2 May 2017

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.

2 May 2017

TAU researchers develop glow stick probes to detect cancerous cells

Chemiluminescence, or chemical light, is the principle behind the glow sticks (also known as light sticks) used at rock concerts and as quick tools to grab when the electricity goes out. But they can also be used to diagnose diseases by identifying concentrations of biological samples.

2 May 2017

Penn study sheds new light on mysterious powers of spider silk genes

They can be stronger than steel at a mere fraction of weight, and also can be tougher and more flexible. Spider silks also tend not to provoke the human immune system. Some even inhibit bacteria and fungi, making them potentially ideal for surgery and medical device applications.

2 May 2017

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

Powerful pain medicine may help reduce vision damage of glaucoma

The tip of our optic nerve is typically the first place injured by glaucoma. Now researchers want to know if the powerful pain medicine (+)-pentazocine can help avoid the damage.

2 May 2017

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

A noninvasive PET imaging method that measures granzyme B, a protein released by immune cells to kill cancer cells, was able to distinguish mouse and human tumors that responded to immune checkpoint inhibitors from those that did not respond early in the course of treatment.

1 May 2017

Experts highlight need for further research on differences between milk proteins

New knowledge on milk composition and quality is of essential importance to consumers as well as the industry. There are therefore considerable research efforts in milk worldwide.

28 Apr 2017

Newly discovered molecule plays central role in appetite control mechanisms

A newly discovered molecule increases appetite during fasting -- and decreases it during gorging. The neuron-exciting protein, named NPGL - apparently aims to maintain body mass at a constant, come feast or famine. An evolutionary masterstroke, but not great news for those looking to trim down -- or beef up for the summer.

28 Apr 2017

Researchers discover new mechanism that causes chronic intestinal inflammation

Researchers at the University Medical Center of Johannes Gutenberg University Mainz and the German Research Center for Environmental Health, Helmholtz Zentrum München have discovered that too much of the oncogene Bcl-3 leads to chronic intestinal diseases.

28 Apr 2017

Protein C News and Research

Study finds no link between gluten intake and heart disease risk in people without celiac disease

TSRI study reveals clues to where tumor metastases are born

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Researchers uncover new mechanism that explains cause of portal hypertension

Discovery of protein that causes liver disease brings hope for new treatments

Researchers use simple blood tests to improve treatment for resistant hypertension in Africa

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

Researchers uncover new potential target for treating spinal muscular atrophy

Researchers uncover molecule that may explain smoking-CHD connection

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

Combination therapy may be effective option for treating some women with ovarian cancer

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

TAU researchers develop glow stick probes to detect cancerous cells

Penn study sheds new light on mysterious powers of spider silk genes

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

Powerful pain medicine may help reduce vision damage of glaucoma

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

Experts highlight need for further research on differences between milk proteins

Newly discovered molecule plays central role in appetite control mechanisms

Researchers discover new mechanism that causes chronic intestinal inflammation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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