Laboratory News and Research

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Study links vitamin D deficiency to accelerated aging of bones

Everyone knows that as we grow older our bones become more fragile. Now a team of U.S. and German scientists led by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley has shown that this bone-aging process can be significantly accelerated through deficiency of vitamin D - the sunshine vitamin.

11 Jul 2013

Research finding may offer novel path for cancer drug design

Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.

10 Jul 2013

Agreement expands national presence of Cleveland Clinic Laboratories

Cleveland Clinic Laboratories will now be the main provider of specialized testing and diagnostics services for ACL Laboratories, one of the largest hospital system laboratories in the United States.

10 Jul 2013

Researchers discover new class of antimalarial compounds

Despite renewed global efforts for eradication, malaria continues to exert devastating effects on human health. An estimated 220 million people are infected each year by malaria-causing Plasmodium parasites, which are transmitted by the bite of an infected mosquito. This enormous infection burden leads to some 660,000 lives lost to malaria each year, the majority of these young children in sub-Saharan Africa. While a vaccine to prevent malaria remains elusive, we depend on antimalarial compounds both to treat infections and prevent disease.

10 Jul 2013

Study examines whether better sleep lowers risk of heart disease

The University of South Florida College of Nursing is conducting research to improve sleep in those caring for people with dementia and Alzheimer's disease, with the aim of determining if better sleep affects heart health.

10 Jul 2013

Psychologists find that bad night's sleep worsens relationship conflicts

Relationship problems can keep us awake at night. But new research from UC Berkeley suggests that sleepless nights also can worsen lovers' fights.

10 Jul 2013

Researchers show cerebrovascular disease affecting blood circulation in brain associated with dementia

Researchers in the Perelman School of Medicine at the University of Pennsylvania found that, across a variety of neurodegenerative diseases, cerebrovascular disease affecting circulation of blood in the brain was significantly associated with dementia.

10 Jul 2013

Soy protein supplement does not reduce recurrence of prostate cancer post radical prostatectomy

Among men who had undergone radical prostatectomy, daily consumption of a beverage powder supplement containing soy protein isolate for 2 years did not reduce or delay development of biochemical recurrence of prostate cancer compared to men who received placebo, according to a study in the July 10 issue of JAMA.

10 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Age-old practice of annual screening exams for cervical cancer may be harmful than helpful

For decades, women between the ages of 21 and 69 were advised to get annual screening exams for cervical cancer. In 2009, however, accumulating scientific evidence led major guideline groups to agree on a new recommendation that women be screened less frequently: every three years rather than annually.

10 Jul 2013

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile - established when it afflicted the New York Yankees' Lou Gehrig - ALS remains a disease that scientists are unable to predict, prevent, or cure.

10 Jul 2013

Viewpoints: Health care's hidden consensus; Examining the fee-for-service payment system; Alternative medicine's allure

The politicians' consensus is that health care reform shouldn't alter or disrupt the way the majority of Americans get their insurance today. ... The policy consensus, though, is that the status quo is actually the problem, and that it deserves to be threatened, undermined and replaced as expeditiously as possible. Wonks of the left and right disagree on what that replacement should look like. But they're united in regarding employer-provided coverage as an unsustainable relic (Ross Douthat, 7/6).

9 Jul 2013

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

FORMA Therapeutics and Cancer Research Technology, Ltd., the commercialization company of Cancer Research UK, announced today a bold research initiative to discover innovative tools, technologies and therapeutic drug candidates against a variety of protein homeostasis regulators called, deubiquitinating enzymes.

9 Jul 2013

Middle East respiratory syndrome coronavirus currently unlikely to cause a pandemic, finds study

New estimates of the transmissibility of the Middle East respiratory syndrome coronavirus (MERS-CoV) in humans suggest that it does not yet have pandemic potential, according to research published in The Lancet.

9 Jul 2013

Stem cells in the aesthetic industry: an interview with Dr. Norma Kassardjian

Stem Cells are special “master” cells in your body. Stem cells are the building blocks that can replicate into other kinds of cells like blood cells, heart, muscle, blood vessels and cartilage.

9 Jul 2013

Physicians have new resource for managing disease in patients with early-stage breast cancer

Physicians have a new resource for managing disease in patients with early-stage breast cancer. Patients diagnosed with ductal carcinoma in situ -- cancer that has not left the breast ducts -- now have the benefit of a multi-gene analysis that considers gene patterns to individualize therapy and determine the chance for recurrence, potentially sparing the patient additional therapy.

9 Jul 2013

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

9 Jul 2013

Macrophages play essential role in production of progesterone hormone

New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.

9 Jul 2013

Oklahoma Norman campus researchers receive OCAST grants for health research projects

Four University of Oklahoma Norman campus researchers were awarded OCAST grants for health research projects on subjects that range from the development of bone grafts using adult stem cells to the identification of genes to block parasite development in mosquitoes to new drug development pipelines to improvements in limb movement.

9 Jul 2013

New low-cost method of in-vitro fertilization may help infertile couples in developing countries

A new low-cost method of in-vitro fertilization developed at the University of Colorado Boulder that performed successfully in recent human clinical trials in Belgium may help thousands of infertile couples in developing countries.

9 Jul 2013

Laboratory News and Research

Study links vitamin D deficiency to accelerated aging of bones

Research finding may offer novel path for cancer drug design

Agreement expands national presence of Cleveland Clinic Laboratories

Researchers discover new class of antimalarial compounds

Study examines whether better sleep lowers risk of heart disease

Psychologists find that bad night's sleep worsens relationship conflicts

Researchers show cerebrovascular disease affecting blood circulation in brain associated with dementia

Soy protein supplement does not reduce recurrence of prostate cancer post radical prostatectomy

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Age-old practice of annual screening exams for cervical cancer may be harmful than helpful

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Viewpoints: Health care's hidden consensus; Examining the fee-for-service payment system; Alternative medicine's allure

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

Middle East respiratory syndrome coronavirus currently unlikely to cause a pandemic, finds study

Stem cells in the aesthetic industry: an interview with Dr. Norma Kassardjian

Physicians have new resource for managing disease in patients with early-stage breast cancer

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

Macrophages play essential role in production of progesterone hormone

Oklahoma Norman campus researchers receive OCAST grants for health research projects

New low-cost method of in-vitro fertilization may help infertile couples in developing countries

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