Laboratory News and Research

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Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors.

26 Jun 2013

UC professor receives Biemann Medal from ASMS for significant achievement in mass spectrometry

Yinsheng Wang, a professor of chemistry at the University of California, Riverside, has received the Biemann Medal, awarded by the American Society for Mass Spectrometry (ASMS) to an individual early in his or her career in recognition of significant achievement in basic or applied mass spectrometry.

26 Jun 2013

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Investigators from the Centers for Disease Control and Prevention describe pathologic findings from 40 case reports of fungal infection in patients who had been given contaminated epidural, paraspinal, or intra-articular (into joints) steroid injections and correlate these findings with clinical and laboratory data.

26 Jun 2013

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches.

26 Jun 2013

A paradigm shift for treatment of muscular dystrophy

Researchers at Boston University College of Health & Rehabilitation Sciences: Sargent College have identified a combinatorial therapeutic approach that has proven effective in treating muscular dystrophy in a mouse model.

26 Jun 2013

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives FDA clearance

BioFire Diagnostics, Inc., announced today the FDA clearance of its FilmArray Blood Culture Identification Panel. To date, the 27-target panel is the most comprehensive test to be approved by the FDA.

26 Jun 2013

Scientist discovers key mutations that sparked hormonal revolution 500 million years ago

Evolution, it seems, sometimes jumps instead of crawls. A research team led by a University of Chicago scientist has discovered two key mutations that sparked a hormonal revolution 500 million years ago.

25 Jun 2013

Study questions the beneficial effects of polyphenols on combating cardiovascular disease

Eating fruit or having a glass of red wine is seen as offering health benefits. The benefits are often pinned on polyphenols, natural chemicals—found in foods—referred to as flavonoids and phenolic acids, but also fragments of food proteins called peptides.

25 Jun 2013

Panasonic’s CO2 cell culture incubators deliver outstanding environmental reliability

Increasingly stringent regulation and the need for absolute sample security when working with human materials heightens the need for laboratory instrumentation that performs to the highest standards. Panasonic MCO-19 CO2 cell culture incubators deliver outstanding environmental reliability.

From PHC Europe B.V. 25 Jun 2013

Thermo Fisher Scientific and Newman-Lakka Institute collaborate to develop new diagnostic approaches for personalized cancer treatment

Thermo Fisher Scientific Inc., the world leader in serving science, and the Newman-Lakka Institute for Personalized Cancer Care at Floating Hospital for Children at Tufts Medical Center, announced an intended collaboration for research and development of new methods to detect and track circulating biomarkers in blood.

25 Jun 2013

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism, and bipolar disorder, according to new research by UC San Francisco scientists.

25 Jun 2013

Researchers find RNA molecule that interferes with lipoprotein production, reduces hyperlipidemia

Hyperlipidemia, a condition with high levels of fats circulating in the bloodstream, is a known risk factor for various cardiovascular and metabolic disorders. While the Western diet often contributes to high levels of lipids such as cholesterol and triglycerides, over-production of the body's own lipoproteins can lead to hyperlipidemia, independent of food intake.

25 Jun 2013

Research findings could lead to new potential treatment for multiple sclerosis

Myelin, the fatty coating that protects neurons in the brain and spinal cord, is destroyed in diseases such as multiple sclerosis. Researchers have been striving to determine whether oligodendrocytes, the cells that produce myelin, can be stimulated to make new myelin. Using live imaging in zebrafish to track oligodendrocytes in real time, researchers reporting in the June 24 issue of the Cell Press journal Developmental Cell discovered that individual oligodendrocytes coat neurons with myelin for only five hours after they are born. If the findings hold true in humans, they could lead to new treatment strategies for multiple sclerosis.

25 Jun 2013

Researchers provide new revelations about intricate pathways involved in turning on T cells

A major study from researchers at the La Jolla Institute for Allergy and Immunology provides new revelations about the intricate pathways involved in turning on T cells, the body's most important disease-fighting cells, and was published today in the prestigious scientific journal Nature.

24 Jun 2013

Compared with Medicaid enrollees, low-income uninsured adults are less likely to have chronic conditions

Compared with adults already enrolled in Medicaid, low-income uninsured adults who may be eligible for Medicaid under the Affordable Care Act were less likely to have chronic conditions such as hypertension, diabetes, and hypercholesterolemia, although those with 1 of these conditions were less likely to be aware they had it or to have the disease controlled, according to a study in the June 26 issue of JAMA. The study is being released early to coincide with its presentation at the AcademyHealth annual research meeting.

24 Jun 2013

First Edition: June 21, 2013

Today's headlines include reports about the rebates some insurers will provide to consumers as a result of a health law provision.

21 Jun 2013

TSRI neuroscientists fill in significant gap in the understanding of how neurons mature

Neuroscientists at The Scripps Research Institute have filled in a significant gap in the scientific understanding of how neurons mature, pointing to a better understanding of some developmental brain disorders.

21 Jun 2013

Th17 lymphocyte: The master coordinator of cellular inflammation in vessel wall

Every year, more than 16,000 Americans die as a result of what's known as an "aortic dissection" - a catastrophic rupture of the aorta, the body's largest artery. Once thought to be a simple structural failure, aortic dissection is now understood to be caused by an inflammatory process that weakens the artery's walls.

21 Jun 2013

Thirdhand smoke causes significant genetic damage in human cells

A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke-the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out-causes significant genetic damage in human cells.

21 Jun 2013

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to Moffitt Cancer Center research.

21 Jun 2013

Laboratory News and Research

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

UC professor receives Biemann Medal from ASMS for significant achievement in mass spectrometry

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

A paradigm shift for treatment of muscular dystrophy

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives FDA clearance

Scientist discovers key mutations that sparked hormonal revolution 500 million years ago

Study questions the beneficial effects of polyphenols on combating cardiovascular disease

Panasonic’s CO2 cell culture incubators deliver outstanding environmental reliability

Thermo Fisher Scientific and Newman-Lakka Institute collaborate to develop new diagnostic approaches for personalized cancer treatment

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Researchers find RNA molecule that interferes with lipoprotein production, reduces hyperlipidemia

Research findings could lead to new potential treatment for multiple sclerosis

Researchers provide new revelations about intricate pathways involved in turning on T cells

Compared with Medicaid enrollees, low-income uninsured adults are less likely to have chronic conditions

First Edition: June 21, 2013

TSRI neuroscientists fill in significant gap in the understanding of how neurons mature

Th17 lymphocyte: The master coordinator of cellular inflammation in vessel wall

Thirdhand smoke causes significant genetic damage in human cells

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

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