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Study identifies a new detrimental effect of genes that cause inherited diseases

Scientists have identified a new detrimental effect of genes that cause inherited diseases, publishing their results today in eLife.

12 Oct 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021

New modeling highlights the role of socio-economic status in Covid-19 transmission in Kenya

Combining data on antibody prevalence, PCR test results, genomic surveillance and population mobility from smartphones has allowed infectious disease modelers to explain the evolution of the first three Covid-19 waves that have affected Kenya since the start of the pandemic.

12 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

A new study assesses antibody and functional T-cell responses at 6 months after complete vaccination with the Pfizer-BioNTech vaccine.

11 Oct 2021

New molecular understanding of variations in salmonella virulence

Researchers from the University of Seville, in collaboration with the universities of Zaragoza and Kansas (USA), have managed to describe hitherto unknown processes that allow us to understand the virulence of a Salmonella infection.

11 Oct 2021

Research finds different antibody responses following COVID vaccination and natural infection

A new study published in the journal Nature attempted to investigate memory B cell evolution 5 months after vaccination with mRNA vaccines such as Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) in SARS-CoV-2 naïve individuals. The study explored various aspects of memory B cell antibody response like neutralizing response, affinity, epitope targeting, and neutralizing breadth.

10 Oct 2021

Role of S-acylation in SARS-CoV-2 infectivity

A new study published in Developmental Cell investigates S-acylation of the SARS-CoV-2 S protein.

10 Oct 2021

Study traces the evolution of hepatitis B virus since prehistoric times

A study published in the journal Science traces the evolution of the hepatitis B virus from prehistory to the present, revealing dissemination routes and changes in viral diversity. Domingo Carlos Salazar García, researcher from the Prehistory, Archeology and Ancient History Department of the University of Valencia, has participated in this study led by the Max Planck Institute for the Science of Human History (Germany).

8 Oct 2021

Referential alarm calling elicits future vigilance in brood parasite hosts

Yellow warblers are hosts to brood parasitic brown-headed cowbirds, which rely on other species to raise their offspring. Warblers use referential "seet" calls to warn female warblers specifically of the brood parasitic brown-headed cowbirds that may try to lay eggs in their nests.

8 Oct 2021

Machine learning algorithms accelerate the protein engineering process

Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts.

7 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Novel technique enables 3D visualization of cells containing melanin pigment

To understand the biological underpinnings of skin and hair pigmentation and related diseases such as albinism or melanoma, scientists and doctors need quantitative, three-dimensional information about the architecture, content and location of pigment cells. Penn State College of Medicine researchers have developed a new technique that allows scientists to visualize every cell containing melanin pigment in 3D, in whole zebrafish.

6 Oct 2021

Study uncovers a gene that plays key role in the evolution of limb development

University of Kentucky College of Medicine researchers were part of a new study that gives insight into how limb development evolved in vertebrates.

5 Oct 2021

Emergence and evolution of endemic and emerging coronavirus diversity in humans and animals

A study aimed to understand the evolutionary and epidemiology dynamics of coronavirus diversity in animals, humans, and wildlife at ecosystem interfaces.

5 Oct 2021

New mathematical tool used to study the genetic interactions associated with cancer

Biologists at Cold Spring Harbor Laboratory are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems.

5 Oct 2021

What makes SARS-CoV-2 variants more virulent?

Researchers in the Republic of Korea have conducted a study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that could help to inform further studies investigating the increased virulence of variants of concern and interest.

4 Oct 2021

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

A new study aimed to analyze the nasopharyngeal microbiota of patients who were hospitalized with COVID-19.

4 Oct 2021

Prevalence of adaptive and prolonged infections’ mutations in receptor-binding domain of SARS-CoV-2 spike protein

A new study used the available nucleotide sequence data on the NCBI COVID-19 database and estimated the global prevalence of adaptive and prolonged infections' mutations in the RBD of the S protein.

4 Oct 2021

REGEN-COV shown to reduce risk of COVID-19–related hospitalization or death from any cause

The phase 1-2 clinical trials conducted using REGEN-COV had shown promising therapeutic benefits in COVID-19 outpatients. Its effect was further investigated in the present phase 3 clinical trial, the findings of which have been published in the "The New England Journal of Medicine".

3 Oct 2021

Evolution News and Research

Study identifies a new detrimental effect of genes that cause inherited diseases

Single-genome sequencing reveals malaria parasite genetics and evolution

New modeling highlights the role of socio-economic status in Covid-19 transmission in Kenya

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

New molecular understanding of variations in salmonella virulence

Research finds different antibody responses following COVID vaccination and natural infection

Role of S-acylation in SARS-CoV-2 infectivity

Study traces the evolution of hepatitis B virus since prehistoric times

Referential alarm calling elicits future vigilance in brood parasite hosts

Machine learning algorithms accelerate the protein engineering process

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Novel technique enables 3D visualization of cells containing melanin pigment

Study uncovers a gene that plays key role in the evolution of limb development

Emergence and evolution of endemic and emerging coronavirus diversity in humans and animals

New mathematical tool used to study the genetic interactions associated with cancer

What makes SARS-CoV-2 variants more virulent?

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

Prevalence of adaptive and prolonged infections’ mutations in receptor-binding domain of SARS-CoV-2 spike protein

REGEN-COV shown to reduce risk of COVID-19–related hospitalization or death from any cause

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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