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GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

German scientists design molecular paintbrush technique to control and monitor key intracellular processes

The plasma membrane serves as a major hub for signal cascades to control crucial cellular processes. But it is a fluid medium, which makes the signaling processes difficult to monitor.

31 Mar 2017

Novel Research Grants bring new insight to complexities of lupus

The Lupus Research Alliance announced today the Novel Research Grant Class of 2017. The Lupus Research Alliance Novel Research Grants, the proven platform for innovation, make discovery and scientific progress possible.

30 Mar 2017

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

Researchers from the Epigenetics and Cancer Biology Program led by Dr. Manel Esteller at the Bellvitge Biomedical Research Institute have discovered how an epigenetic lesion can lead to T-cell acute lymphoblastic leukemia.

30 Mar 2017

Fluctuation in intracellular calcium ion concentration impacts brain shape

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Assistant Professor Makoto Suzuki of the National Institute for Basic Biology, Professor Naoto Ueno, and their colleagues have shown that during the process of neural tube formation a transient increase in the concentration of calcium ions in cells causes these morphological changes and is essential for neural tube formation.

30 Mar 2017

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Even a single dose of a specific ribonucleic acid molecule, known as a small interfering RNA (siRNA), offers patients at high risk of cardiovascular disease long-lasting protection against high LDL cholesterol - one of the main risk factors for heart attack and stroke.

30 Mar 2017

Finalists for Pittcon's excellence awards released

Pittcon, the world’s leading conference and exposition for laboratory science, is pleased to announce the selection of eight finalists in the first ever Pittcon Today Excellence Awards conducted by CE Communications, official publishers of Pittcon Today and Pittcon Buzz.

From Pittcon 30 Mar 2017

Study shows protective link between consumption of legumes and risk of developing type 2 diabetes

Legumes are a food group rich in B vitamins, contain different beneficial minerals (calcium, potassium and magnesium) and sizeable amounts of fibre and are regarded as a low-glycemic index food, which means that blood glucose levels increase only slowly after consumption.

30 Mar 2017

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

By engineering an on/off switch into a weakened form of HIV, University of Nebraska-Lincoln researchers have enhanced the safety and effectiveness of a potential vaccine for the virus that has killed approximately 35 million people during the past 35 years.

30 Mar 2017

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Natural genetic changes can put some people at high risk of certain conditions, such as breast cancer, Alzheimer's disease or high blood pressure. But in rare cases, genetic errors also can have the opposite effect, protecting individuals with these helpful genetic mistakes from developing common diseases.

30 Mar 2017

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

An article published in Experimental Biology and Medicine identifies a new signaling pathway involved in breast cancer cell growth. The study, led by Dr. Chan-Wha Kim, from the Department of Biotechnology at Korea University in Seoul, reports that inhibition of the actin-binding protein transgelin prevents vasculogenic mimicry (VM), a process that provides tumor cells with the nutrients required for growth.

29 Mar 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017

Scientists developing new method for drug discovery using simple models and small data sets

Drug discovery is in essence the designing of compounds to interact with disease-related proteins. And in many recent development efforts, this process increasingly relies on "big data" and complex "deep learning", requiring the harnessing of supercomputing power.

29 Mar 2017

Simple finger-prick blood test can help doctors prescribe treatment for depression

Doctors for the first time can determine which medication is more likely to help a patient overcome depression, according to research that pushes the medical field beyond what has essentially been a guessing game of prescribing antidepressants.

29 Mar 2017

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Discoveries of hormones related to weight and appetite in the '90s helped spur a search for obesity treatments targeting those hormones-- with disappointing results.

29 Mar 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis

Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a cellular fuel sensor, known to control energy processes in the cells, is involved in the regulation of the contact of cells with their surrounding environment.

29 Mar 2017

Study identifies how BPA may encourage inflammatory breast cancer growth

The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute.

28 Mar 2017

Survey finds alarming rates of shared decision making for prostate cancer screening

A new study finds that while a blood test that helps to screen for prostate cancer remains common, only 30 percent of men in a large national survey reported having a balanced discussion of the advantages and disadvantages of the screening with their doctor.

28 Mar 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

Protein C News and Research

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

German scientists design molecular paintbrush technique to control and monitor key intracellular processes

Novel Research Grants bring new insight to complexities of lupus

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

Fluctuation in intracellular calcium ion concentration impacts brain shape

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Finalists for Pittcon's excellence awards released

Study shows protective link between consumption of legumes and risk of developing type 2 diabetes

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

Scientists developing new method for drug discovery using simple models and small data sets

Simple finger-prick blood test can help doctors prescribe treatment for depression

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis

Study identifies how BPA may encourage inflammatory breast cancer growth

Survey finds alarming rates of shared decision making for prostate cancer screening

TSRI researchers reveal how viruses incapacitate bacterial defense system

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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