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Research findings may offer new hope to stroke victims

A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims.

24 May 2013

Potential new treatment approaches for liver diseases

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

24 May 2013

Smartphone solutions for clinical trials

mHealth broadly refers to the use of a mobile device to send patient information to or from a medical service provider. In most medication management mobile applications that are out there now, the “information” sent is usually a unidirectional nagging reminder to the patient. The application may populate a diary or it may not.

24 May 2013

Caregivers experience less stress when family members with dementia attend ADS program

Family caregivers of older adults with dementia are less stressed and their moods are improved on days when dementia patients receive adult day services (ADS), according to Penn State researchers.

24 May 2013

Lifestyle behaviors can lower risk of kidney failure in people with CKD

Lifestyle behaviors like working out and improving nutrition can lower the risk of kidney failure in people with chronic kidney disease, according to new research from the University of Alabama at Birmingham.

24 May 2013

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Linneah sat at a desk at the Center for Sexual Medicine at Sheppard Pratt in the suburbs of Baltimore and filled out a questionnaire. She read briskly, making swift checks beside her selected answers, and when she was finished, she handed the pages across the desk to Martina Miller, who gave her a round of pills.

24 May 2013

Spring Bank Pharmaceuticals starts Phase I study of SB 9200 for treatment of HCV infection

Spring Bank Pharmaceuticals, Inc., a biopharmaceutical company developing innovative medicines for the treatment of viral infections, today announced that it has initiated dosing in a Phase I study of SB 9200, its investigational, once daily, oral therapy for the treatment of HCV infection.

24 May 2013

New study determines that children with temporal lobe epilepsy likely to have depression

A new study determined that children and adolescents with seizures involving the temporal lobe are likely to have clinically significant behavioral problems and psychiatric illness, especially depression.

24 May 2013

FDA approves Tina-quant HbA1cDx assay for diagnosis of diabetes

Today the U.S. Food and Drug Administration announced that it is allowing marketing of the COBAS INTEGRA 800 Tina-quant HbA1cDx assay (Tina-quant HbA1cDx assay) for the diagnosis of diabetes by health care professionals.

24 May 2013

Lightlake Therapeutics announces Phase II clinical trial results of nasal spray treatment for BED

Lightlake Therapeutics Inc., a biopharmaceutical company developing addiction treatments based on its expertise in opioid antagonists, announced today that results of the Company's Phase II clinical trial of its nasal spray treatment for Binge Eating Disorder were presented at the American Psychiatric Association Annual Meeting in San Francisco by Professor Hannu Alho, MD, professor of addiction medicine at the University of Helsinki and Principal Investigator for the trial.

23 May 2013

New data highlights urgent crisis posed on US healthcare system by DFUs and VLUs

Organogenesis Inc., a commercial leader in the field of regenerative medicine, presented new data generated in collaboration with a team of expert economists from Analysis Group (a leading health economics consultancy) demonstrating the significant healthcare resource and economic burden that diabetic foot ulcers and venous leg ulcers place upon the US healthcare system.

23 May 2013

Long-term depression linked with life-threatening chronic disease, earlier death

The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk factors have been taken into account.

23 May 2013

Innovative nebulizer to treat cystic fibrosis developed by Cambridge Consultants

Observing surfers with cystic fibrosis (CF) led scientists to discover that the inhaled mist of seawater has a therapeutic effect on the lung problems associated with the disease. Now the findings have been used by pharmaceutical company Parion Sciences and product development firm Cambridge Consultants in a revolutionary new aerosol delivery system. It enables CF sufferers to get the benefits of saltwater treatment in their own homes overnight while they sleep.

23 May 2013

Immune system attacks beneficial bacteria in several chronic human diseases

The human gut is loaded with commensal bacteria - "good" microbes that, among other functions, help the body digest food. The gastrointestinal tract contains literally trillions of such cells, and yet the immune system seemingly turns a blind eye. However, in several chronic human diseases such as inflammatory bowel disease, HIV/AIDS, cancer, cardiovascular disease, and diabetes, the immune system attacks these normally beneficial bacteria, resulting in chronic inflammation and contributing to disease progression.

23 May 2013

Prosonix commences Phase 2 clinical study of PSX1002 for treatment of moderate to severe COPD

Prosonix, an innovative speciality pharmaceutical company developing a portfolio of inhaled Respiratory Medicines by Design, has initiated a Phase 2 clinical study with PSX1002 that will assess its effect on lung function and the safety of a range of doses in patients with moderate to severe chronic obstructive pulmonary disease.

23 May 2013

Study: Sleep disturbance may contribute to depression risk by impairing emotion regulation

A new study provides neurobiological evidence for dysfunction in the neural circuitry underlying emotion regulation in people with insomnia, which may have implications for the risk relationship between insomnia and depression.

23 May 2013

Researchers find that over 40% of patients treated for COPD did not actually have the disease

More than 40 percent of patients being treated for COPD at a federally funded clinic did not have the disease, researchers found after evaluating the patients with spirometry, the diagnostic "gold standard" for chronic obstructive pulmonary disease.

23 May 2013

MUC5B gene variation improves survival in patients with idiopathic pulmonary fibrosis

Variation in the gene MUC5B among patients with idiopathic pulmonary fibrosis was associated with improved survival, according to a study published online by JAMA. The study is being released early online to coincide with its presentation at the American Thoracic Society international conference.

22 May 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

Systemic inflammation is linked with depression in COPD patients, say researchers

Depression is common in patients with chronic obstructive pulmonary disease (COPD) and has been linked with disease severity and impaired quality of life. Now, for the first time, researchers at the University of Pittsburgh have linked the systemic inflammation associated with COPD with depression in these patients.

22 May 2013

Chronic News and Research

Research findings may offer new hope to stroke victims

Potential new treatment approaches for liver diseases

Smartphone solutions for clinical trials

Caregivers experience less stress when family members with dementia attend ADS program

Lifestyle behaviors can lower risk of kidney failure in people with CKD

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Spring Bank Pharmaceuticals starts Phase I study of SB 9200 for treatment of HCV infection

New study determines that children with temporal lobe epilepsy likely to have depression

FDA approves Tina-quant HbA1cDx assay for diagnosis of diabetes

Lightlake Therapeutics announces Phase II clinical trial results of nasal spray treatment for BED

New data highlights urgent crisis posed on US healthcare system by DFUs and VLUs

Long-term depression linked with life-threatening chronic disease, earlier death

Innovative nebulizer to treat cystic fibrosis developed by Cambridge Consultants

Immune system attacks beneficial bacteria in several chronic human diseases

Prosonix commences Phase 2 clinical study of PSX1002 for treatment of moderate to severe COPD

Study: Sleep disturbance may contribute to depression risk by impairing emotion regulation

Researchers find that over 40% of patients treated for COPD did not actually have the disease

MUC5B gene variation improves survival in patients with idiopathic pulmonary fibrosis

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

Systemic inflammation is linked with depression in COPD patients, say researchers

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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