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Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Galapagos NV and AbbVie announced today an extension of their GLPG0634 clinical development collaboration to include Crohn's disease. Galapagos will fund and complete a Phase 2 program in Crohn's disease, which is designed to facilitate rapid progression into Phase 3.

17 May 2013

Communication with parents has effects on college students' eating and physical activity behaviors

College students eat more fruits and vegetables and exercise more on days when they communicate more with their parents, according to researchers at Penn State.

17 May 2013

Women with chronic physical disabilities do become pregnant, new study finds

Like the general public, health care professionals may hold certain stereotypes regarding sexual activity and childbearing among women with disabilities. But a new study finds that women with chronic physical disabilities are about as likely as nondisabled women to say they are currently pregnant, after age and other sociodemographic factors are taken into account.

17 May 2013

New research reveals how endothelium maintains highly efficient barrier function

The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely withstands blood flow, hydrostatic pressure, stretch and tissue compression to create a unique and highly dynamic barrier that maintains the organization necessary to partition tissues from the body's circulatory system.

17 May 2013

Robotic transplantation may reduce health disparities for obese patients with chronic kidney failure

Obese patients who received robotic kidney transplants had fewer wound complications than patients who received traditional "open" transplant surgery, according to surgeons at the University of Illinois Hospital & Health Sciences System.

17 May 2013

Simvastatin hinders positive effects of exercise for obese adults, say researchers

Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combination of medical disorders including excess body fat and/or high levels of blood pressure, blood sugar and/or cholesterol.

17 May 2013

Changes in specific proteins contribute to 'leaky-gut' wall

Scientists at Trinity College Dublin have made an important advance in understanding the biological factors that keep the lining of the gut wall intact. Associate Professor, Maria O'Sullivan at Trinity's School of Medicine and St James's Hospital and colleagues, showed that changes in specific proteins may contribute to a 'leaky-gut' wall which may have important implications for common chronic digestive diseases such as irritable bowel syndrome and inflammatory bowel disease.

17 May 2013

LDL cholesterol less useful in assessing kidney disease patients' cardiovascular health

LDL cholesterol is not a useful marker of heart disease risk in patients with kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

17 May 2013

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body.

17 May 2013

Depressive symptoms linked to early death in cancer survivors

Depressed cancer survivors are twice as likely to die prematurely than those who do not suffer from depression, irrespective of the cancer site. That's according to a new study, by Floortje Mols and colleagues, from Tilburg University in The Netherlands.

17 May 2013

Pennsylvania receives grant to design state healthcare innovation plan

Governor Tom Corbett today announced that Pennsylvania was awarded a $1.5 million grant from the Center for Medicare and Medicaid Innovation to design a state healthcare innovation plan.

17 May 2013

Researchers reveal new molecular mechanisms that resist visceral leishmaniasis

Researchers from CNRS, Université Toulouse III - Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection.

16 May 2013

People suffering from PTSD have risk of developing type 2 diabetes

The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gieβen and Marburg who worked with data from the population-based KORA cohort study.

16 May 2013

American Association for Respiratory Care names Jefferson a Quality Respiratory Care Institution

Thomas Jefferson University Hospital was recently bestowed the title of "Quality Respiratory Care Institution" for 2013 by the American Association for Respiratory Care.

16 May 2013

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia, according to a study led in part by Dana-Farber Cancer Institute investigators.

16 May 2013

$Study: Long-term mortality in patients with refractory angina is surprisingly low$

Study: Long-term mortality in patients with refractory angina is surprisingly low

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and improving the quality of life in these patients according to an article published online this week in the European Heart Journal.

16 May 2013

Community Catalyst study shows dental therapists expand access to people in remote areas

Lack of access to dental care in the United States has reached epic proportions. Dental disease is the number one chronic illness affecting children - more common than asthma. The Institute of Medicine clearly states that the current dental delivery system doesn't work for a third of the people in the U.S.

16 May 2013

Chronic News and Research

Galapagos, AbbVie announce extension of GLPG0634 clinical development collaboration

Communication with parents has effects on college students' eating and physical activity behaviors

Women with chronic physical disabilities do become pregnant, new study finds

New research reveals how endothelium maintains highly efficient barrier function

Robotic transplantation may reduce health disparities for obese patients with chronic kidney failure

Simvastatin hinders positive effects of exercise for obese adults, say researchers

Changes in specific proteins contribute to 'leaky-gut' wall

LDL cholesterol less useful in assessing kidney disease patients' cardiovascular health

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Depressive symptoms linked to early death in cancer survivors

Pennsylvania receives grant to design state healthcare innovation plan

Researchers reveal new molecular mechanisms that resist visceral leishmaniasis

People suffering from PTSD have risk of developing type 2 diabetes

American Association for Respiratory Care names Jefferson a Quality Respiratory Care Institution

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

Study: Long-term mortality in patients with refractory angina is surprisingly low

Community Catalyst study shows dental therapists expand access to people in remote areas

Simponi injection gets FDA approval to treat adults with ulcerative colitis

Research shows fish oils could minimize effects of junk food on brain

Study shows drama therapy improves mood and reduces pain for hemodialysis patients

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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