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Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

It has been estimated that the number of people with diabetes worldwide reached 422 million in 2014, boosting prevalence to 8.5% among adults over 18 years of age. This figure is expected to rise to 642 million people by 2040.

16 Mar 2017

Refugees with PTSD regulate stress differently than individuals without the disorder, study finds

New Michigan State University research has found that refugees diagnosed with post-traumatic stress disorder regulate stress differently than those who don't have the disorder, but may have experienced similar suffering.

16 Mar 2017

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues.

15 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Antibody treats pediatric brain tumors safely and effectively in mice

Five types of pediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumors without hurting healthy brain cells, according to a new study by researchers at the Stanford University School of Medicine.

15 Mar 2017

New study sheds light on how dance moves matter in biological courtship

At every moment inside the human body, a carefully choreographed dance is being performed.

15 Mar 2017

Researchers make surprising and crucial discovery about Alexander disease

Researchers at the University of Wisconsin-Madison have made a surprising and potentially crucial discovery about Alexander disease, a rare and fatal neurological disorder with no known cure.

15 Mar 2017

Bacterial cell counting and sizing using the Multisizer

In this interview, Dr. Rich Jones introduces bacterial cell counting and an example of when the Multisizer 4e from Beckman Coulter has been used for this application.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 15 Mar 2017

Researchers devise new way of creating common anti-malarial medication

Researchers at Cardiff University have devised a new way of creating a drug commonly used as the first line of defence against malaria around the world.

15 Mar 2017

Breakthrough brain repair discovery could revolutionise treatment of Multiple Sclerosis

Queen's University Belfast scientists have discovered that specific cells from the immune system are key players in brain repair - a fundamental breakthrough that could revolutionise the treatment of debilitating neurological disorders such as Multiple Sclerosis.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Defect in non-coding DNA could give rise to language impairments in children

The human genome is made up of ~3 billion letters of DNA and at each position it is possible to have different letters, called variants. Some variants are harmless but others can be detrimental, making it a mammoth task to find out which variants cause a disorder.

14 Mar 2017

New research project unravels disease mechanisms of schizophrenia

Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia.

14 Mar 2017

New technique opens door for biochemists to create better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader.

14 Mar 2017

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Howard Hughes Medical Institute researchers have introduced a genetic mutation found in some patients with early onset Parkinson's disease into mice, creating a new animal model of the disease.

14 Mar 2017

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Beneficial bacteria may be the key to helping to reverse a cycle of gut inflammation seen in certain inflammatory bowel diseases, University of North Carolina Lineberger Comprehensive Cancer Center researchers have found.

13 Mar 2017

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund - the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed to be at the root of Alzheimer's disease.

13 Mar 2017

Evolution of immuno-oncology

Immuno-oncology did not exist four years ago, it's a term coined by Dr. Axel Hoos, Head of the newly defined immuno-oncology department at GSK. He is also Senior Vice President Therapeutic Area (TA) and Head for Oncology R&D. Previously, it was referred to as cancer immunotherapy, but now it is called immuno-oncology (IO).

13 Mar 2017

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma — the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry.

10 Mar 2017

Protein C News and Research

Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

Refugees with PTSD regulate stress differently than individuals without the disorder, study finds

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

LJI researchers unravel molecular underpinnings of exhausted T cells

Antibody treats pediatric brain tumors safely and effectively in mice

New study sheds light on how dance moves matter in biological courtship

Researchers make surprising and crucial discovery about Alexander disease

Bacterial cell counting and sizing using the Multisizer

Researchers devise new way of creating common anti-malarial medication

Breakthrough brain repair discovery could revolutionise treatment of Multiple Sclerosis

Researchers suggest potential new way to restore healthy intestinal function in older people

York researchers move closer to finding new treatments for chronic bladder diseases

Defect in non-coding DNA could give rise to language impairments in children

New research project unravels disease mechanisms of schizophrenia

New technique opens door for biochemists to create better therapeutic antibodies

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Evolution of immuno-oncology

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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