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FDA clears Insmed IND for ARIKACE Phase 3 clinical trial in nontuberculous mycobacteria lung infections

Insmed Incorporated, a biopharmaceutical company, announced today that the Company's Investigational New Drug Application (IND) to conduct a pivotal Phase 3 clinical trial of ARIKACE™ (liposomal amikacin for inhalation) in nontuberculous mycobacteria (NTM) lung infections has been cleared by the U.S. Food and Drug Administration (FDA).

21 Mar 2011

Life Technologies enters clinical trials for DNA SBT platform for analysis of Human Leukocyte Antigen system

Life Technologies Corporation today announced that it is the first life science tools provider entering clinical trials to prove the safety and effectiveness of their DNA sequence-based typing (SBT) platform for analysis of the Human Leukocyte Antigen (HLA) system. Submission for 510(k) clearance of this SBT platform will follow completion of the clinical trials, which is anticipated this summer.

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

EDMA endorses the campaign against excessive use of salt

EDMA, the European Diagnostic Manufacturers Association, fully endorses the 2011 World Salt Awareness Week theme “Salt and Men’s Health” as the latter reminds that more men than women die prematurely of cardiovascular diseases (CVD).

21 Mar 2011

U-M professor shows how plasticity of brain restores critical functions related to learning, memory

When Geoffrey Murphy, Ph.D., talks about plastic structures, he's not talking about the same thing as Mr. McGuire in The Graduate. To Murphy, an associate professor of molecular and integrative physiology at the University of Michigan Medical School, plasticity refers to the brain's ability to change as we learn.

19 Mar 2011

ACRIN, ECOG, NCI intent to merge their clinical cancer research programs

The American College of Radiology's Imaging Network and the Eastern Cooperative Oncology Group, National Cancer Institute Clinical Trials Cooperative Group members, today announced their intent to merge their clinical cancer research programs.

19 Mar 2011

Scientists devise new strategy to prevent spread of drug-resistant bacteria

A team of scientists from the University of Oxford, U.K. have taken lessons from Adam Smith and Charles Darwin to devise a new strategy that could one day slow, possibly even prevent, the spread of drug-resistant bacteria. In a new research report published in the March 2011 issue of GENETICS, the scientists show that bacterial gene mutations that lead to drug resistance come at a biological cost not borne by nonresistant strains.

19 Mar 2011

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced publication of a clinical study in the Journal of Clinical Lipidology demonstrating that in many people, low density lipoprotein cholesterol is a less accurate predictor of cardiovascular disease events than LDL particle number.

19 Mar 2011

CDC to award $2M grant to continue CARPE program in preventing healthcare-associated infections

The federal Centers for Disease Control and Prevention is awarding researchers at the Cook County Health & Hospitals System and Rush University Medical Center a $2 million grant to continue a successful program aimed at preventing healthcare-associated infections, antibiotic resistance, and other adverse events associated with healthcare.

19 Mar 2011

BUSM professors highlight increased risks of naturally occurring infections

Paul Duprex, PhD, and Elke M-hlberger, PhD, both associate professors of microbiology at Boston University School of Medicine, recently co-authored a commentary about viruses for Microbiology Today, the monthly publication of the Society of General Microbiology, which is the largest microbiological society in Europe.

19 Mar 2011

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Polaris Group announced today the enrollment of the first patient in a Phase 2 clinical trial of ADI-PEG 20, the company's novel enzyme-based treatment for malignant mesothelioma.

19 Mar 2011

Scientists to develop new MR imaging techniques for brain study

A Norwegian research centre is developing new magnetic resonance imaging techniques to study the brain. This could have impact for victims of brain damage as well as Alzheimer patients.

19 Mar 2011

Commentary on the global challenges of emerging viral infections

Paul Duprex, PhD, and Elke Mühlberger, PhD, both associate professors of microbiology at Boston University School of Medicine (BUSM), recently co-authored a commentary about viruses for Microbiology Today, the monthly publication of the Society of General Microbiology, which is the largest microbiological society in Europe. The article focuses on the history of viruses and vaccines and gives their perspective on what is necessary to evolve to the next era of virology research.

18 Mar 2011

RainDance Technologies launches ASDSeq and XSeq Research Screening Panels

RainDance Technologies, Inc., today announced the commercial availability of the ASDSeq™ and XSeq™ Research Screening Panels. Developed in collaboration with Emory University and Greenwood Genetic Center, the two comprehensive panels enable researchers to simultaneously interrogate key genes known to be linked to X-chromosome disorders and syndromic forms of Autism Spectrum Disorder (ASD) using next-generation sequencing.

18 Mar 2011

Celera reports net revenue of $34.9 million for fourth quarter of 2010

Celera Corporation today reported net revenues of $34.9 million for the fourth quarter of 2010 that ended December 25, 2010, compared to $39.2 million for the prior year quarter.

18 Mar 2011

M7T, MGH collaborate to implement Keystone Engine for radiology workflow scenario

Mach 7 Technologies, a global provider of vendor neutral medical image management solutions, has collaborated with Massachusetts General Hospital to implement Keystone Engine to improve a highly specialized radiology department workflow scenario.

18 Mar 2011

UCLA researchers identify new biomarker that can help track amyloid beta in Alzheimer's

UCLA researchers have identified a new biomarker that could help them track how effectively the immune system is able to clear the brain of amyloid beta, which forms the plaques considered one of the hallmarks of Alzheimer's disease.

18 Mar 2011

Vitamin A may play key role in sperm cell formation and development of central nervous system

In a recently-published study mapping the structure and function of the so-called "orphan" nuclear receptor TR4, Van Andel Research Institute (VARI) investigators suggest that Vitamin A may play a more direct role than was previously known in certain physiological functions including sperm cell formation and the development of the central nervous system.

18 Mar 2011

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

Quest Diagnostics Incorporated, the world's leading cancer diagnostics company, today announced that its ColoVantage test has been approved by New York State's Department of Health for testing on samples of patients in the state. It is believed to be the first molecular colorectal cancer detection method that employs a venal blood specimen to be approved by the state.

From Quest Diagnostics 18 Mar 2011

Low calorie diet may delay or prevent aging and neurodegenerative diseases

Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers. A team of scientists from Paul Greengard's Rockefeller University laboratory have linked a molecule that stimulates autophagy with the reduction of one of Alzheimer's disease's major hallmarks, amyloid peptide.

17 Mar 2011

Laboratory News and Research

FDA clears Insmed IND for ARIKACE Phase 3 clinical trial in nontuberculous mycobacteria lung infections

Life Technologies enters clinical trials for DNA SBT platform for analysis of Human Leukocyte Antigen system

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

EDMA endorses the campaign against excessive use of salt

U-M professor shows how plasticity of brain restores critical functions related to learning, memory

ACRIN, ECOG, NCI intent to merge their clinical cancer research programs

Scientists devise new strategy to prevent spread of drug-resistant bacteria

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

CDC to award $2M grant to continue CARPE program in preventing healthcare-associated infections

BUSM professors highlight increased risks of naturally occurring infections

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Scientists to develop new MR imaging techniques for brain study

Commentary on the global challenges of emerging viral infections

RainDance Technologies launches ASDSeq and XSeq Research Screening Panels

Celera reports net revenue of $34.9 million for fourth quarter of 2010

M7T, MGH collaborate to implement Keystone Engine for radiology workflow scenario

UCLA researchers identify new biomarker that can help track amyloid beta in Alzheimer's

Vitamin A may play key role in sperm cell formation and development of central nervous system

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

Low calorie diet may delay or prevent aging and neurodegenerative diseases

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