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New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Suppose you're a teen or young woman who starts putting on fat, mainly in your legs. Doctors say you're obese – but no matter how much you diet and exercise, you can't lose the fat. After years of weight gain, pain, and swelling, you're finally diagnosed with lipedema – a common but "enigmatic" disease of the peripheral fat.

19 Dec 2019

Study hints why some melanomas more likely to spread

Usually starting as a blemish, skin cancer can quickly develop and spread to other parts of the body. The deadliest form of skin cancer, melanoma proliferates rapidly through the lymph nodes, affecting important internal organs. The disease can be variable, wherein some cancer cells never metastasize to the blood and lymph nodes and throughout the body, while others, tend to metastasize.

19 Dec 2019

Experimental Zika vaccine improves fetal outcomes in rhesus macaque model

An experimental Zika vaccine lowered levels of virus in pregnant monkeys and improved fetal outcomes in a rhesus macaque model of congenital Zika virus infection, according to a new study in Science Translational Medicine.

19 Dec 2019

Edematous severe acute malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level - the chemical tags in DNA that help regulate gene expression - between two clinically distinct forms of acute childhood malnutrition known as edematous severe acute malnutrition (ESAM) and non-edematous SAM (NESAM).

19 Dec 2019

Powdered watermelon supplements provide health benefits to obese mice

Eating watermelon in the form of powdered supplements helped adult obese mice avoid some detrimental health effects of an unhealthy diet, according to a new Oregon State University study.

19 Dec 2019

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective.

19 Dec 2019

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

The U.S. Food & Drug Administration granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

19 Dec 2019

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Painful inflammatory lesions of the skin and mucous membranes may occur in children who develop bacterial pneumonia.

19 Dec 2019

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.

19 Dec 2019

Acute mountain sickness medication does not reduce exercise performance at high altitudes

A new study finds that a medication commonly prescribed to prevent and combat symptoms of acute mountain sickness does not reduce exercise performance at high altitudes. This may be especially important for military personnel and first responders not accustomed to working above sea level.

19 Dec 2019

Glutamine could help obese people reduce inflammation of fat tissue

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types.

19 Dec 2019

Gastric bypass associated with higher risk of additional operations

Research from the Harvard Pilgrim Health Care Institute finds that gastric bypass is associated with a higher risk of additional operations or other invasive procedures, compared to a gastric sleeve procedure.

19 Dec 2019

Science has not been able to create a substitute for human blood

Science has been able to create and employ a number of medical marvels, such as the artificial heart and synthetic insulin. But not a substitute for human blood.

19 Dec 2019

Declining dementia rates may be due to generational differences in lifetime lead exposure

To the medical community's surprise, several studies from the US, Canada, and Europe suggest a promising downward trend in the incidence and prevalence of dementia. Important risk factors for dementia, such as mid-life obesity and mid-life diabetes, have been increasing rapidly, so the decline in dementia incidence is particularly perplexing.

19 Dec 2019

Working for long hours linked to greater likelihood of having masked and sustained hypertension

Office workers who spend long hours on the job are more likely to have high blood pressure, including a type that can go undetected during a routine medical appointment, according to a new study published today in the American Heart Association's journal Hypertension.

19 Dec 2019

An innovative treatment for joint pain

Tired of living with painful arthritic knees, 54-year-old Deborah Brown's interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).

18 Dec 2019

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

A fast, inexpensive yet sensitive technique to detect cancer markers is bringing researchers closer to a "liquid biopsy" - a test using a small sample of blood or serum to detect cancer, rather than the invasive tissue sampling routinely used for diagnosis.

18 Dec 2019

Traffic-related pollution increases a pregnant woman’s risk for hypertension

A new report published by the National Toxicology Program (NTP) indicates that air pollution derived from traffic could make a pregnant woman more likely to develop hypertension than otherwise. The study is based on an analysis of the association between traffic-related air pollution, or TRAP, with hypertensive disorders of pregnancy.

18 Dec 2019

New paper-based test for early Lyme diagnosis

A new paper in the journal ACS Nano reports the development of an incredibly cheap and highly sensitive test to diagnose Lyme disease in its earliest stages, when it can be most easily, effectively and inexpensively treated.

18 Dec 2019

Blood News and Research

New antibody shows promise in active lupus

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Study hints why some melanomas more likely to spread

Experimental Zika vaccine improves fetal outcomes in rhesus macaque model

Edematous severe acute malnutrition linked to DNA modification

Powdered watermelon supplements provide health benefits to obese mice

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

Acute mountain sickness medication does not reduce exercise performance at high altitudes

Glutamine could help obese people reduce inflammation of fat tissue

Gastric bypass associated with higher risk of additional operations

Science has not been able to create a substitute for human blood

Declining dementia rates may be due to generational differences in lifetime lead exposure

Working for long hours linked to greater likelihood of having masked and sustained hypertension

An innovative treatment for joint pain

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

Traffic-related pollution increases a pregnant woman’s risk for hypertension

New paper-based test for early Lyme diagnosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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