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Study evaluates patients with regional myocardial wall thinning

Among patients with coronary artery disease referred for cardiovascular magnetic resonance and found to have regional myocardial wall thinning (of the heart muscle), limited scar burden was associated with improved contraction of the heart and reversal of wall thinning after revascularization, suggesting that myocardial thinning is potentially reversible, according to a study appearing in the March 6 issue of JAMA.

7 Mar 2013

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Kidney failure affects 25 million individuals in the U.S. and many more throughout the world. Loss of kidney function means the majority of these patients must undergo dialysis treatments to remove excess fluids and waste products. Although dialysis therapy coupled with medication has improved the life expectancy for people with kidney failure, for unknown reasons, patients' risk of sudden heart failure and death remains 10 to 20 times greater than average.

7 Mar 2013

BIDMC investigator receives $50,000 CCF grant for research on pediatric cardiomyopathy

Maria Kontaridis, PhD, an investigator in the Division of Cardiology at Beth Israel Deaconess Medical Center (BIDMC), has received a $50,000 grant from the Children's Cardiomyopathy Foundation (CCF) for her research on pediatric cardiomyopathy.

7 Mar 2013

Primary Practice Physician Program for Chronic Pain and its impact on patients and providers

Patients who experience chronic pain may experience improvement in symptoms if their primary care providers are specifically trained in multiple aspects of pain, including emotional consequences.

6 Mar 2013

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

In a world first, a team of researchers at the Krembil Neuroscience Centre and the University Health Network have shown that Deep Brain Stimulation (DBS) in patients with chronic, severe and treatment-resistant Anorexia Nervosa (anorexia) helps some patients achieve and maintain improvements in body weight, mood, and anxiety.

6 Mar 2013

FDA accepts AMAG’s Feraheme sNDA for review

AMAG Pharmaceuticals, Inc. today announced that the United States Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use, which was submitted to the FDA in December 2012.

6 Mar 2013

Drug to relieve pain of feline osteoarthritis identified

The non-steroidal anti-inflammatory drug meloxicam significantly improves nighttime physical activity in cats with osteoarthritis, indicating its potential as a pain reliever in this feline population, report Canadian researchers.

6 Mar 2013

Pain self-management and exercise ‘effective in elderly’

Techniques for the self-management of chronic pain based on cognitive behavioral therapy significantly reduce disability, suggest results from a randomized controlled trial in older adults.

6 Mar 2013

UK’s health performance declining compared with 14 EU countries over past 20 years

Six decades of universal free health care, the introduction of widespread public health initiatives (eg, tobacco control, cancer screening, and immunisation), and substantial increases in health expenditure have failed to improve the UK’s health outcomes or longevity ranking against the average of 14 other original members of the European Union, Australia, Canada, Norway, and the USA (EU15+) over the past 20 years.

6 Mar 2013

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

Array BioPharma Inc. and Global Blood Therapeutics today announced a multi-target drug discovery collaboration agreement to identify small molecule lead compounds targeting chronic blood-based diseases.

6 Mar 2013

New tool can help determine senior citizens' 10-year survivability rates

A UC San Francisco team has developed a tool that can help determine - and perhaps influence - senior citizens' 10-year survivability rates.

6 Mar 2013

University of Manchester leads systems medicine research network for inflammatory bowel disease

The University of Manchester is leading a €12 million systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease.

6 Mar 2013

Continuous dyskinesia monitoring technology for Parkinson’s to be developed by Great Lakes NeuroTechnologies

Great Lakes NeuroTechnologies (GLNT) announced today that they are launching commercialization and clinical studies to validate a system for objective, continuous monitoring of dyskinesias associated with Parkinson’s disease.

5 Mar 2013

Benefits of diastolic function improvement in heart failure questioned

The importance of left ventricular diastolic function improvement in patients with heart failure with preserved ejection fraction has been questioned, after researchers found that treatment with spironolactone resulted in some functional improvements but failed to impact on patients’ exercise capacity.

5 Mar 2013

Omalizumab scratches the itch for urticaria patients

The monoclonal antibody omalizumab seems to be effective at relieving symptoms for patients with chronic idiopathic urticaria who have not responded to H1-antihistamine therapy, report US researchers.

5 Mar 2013

FES cycling associated with improvements in individuals with chronic spinal cord injury

A new study by Kennedy Krieger Institute's International Center for Spinal Cord Injury finds that long-term lower extremity functional electrical stimulation (FES) cycling, as part of a rehabilitation regimen, is associated with substantial improvements in individuals with chronic spinal cord injury (SCI).

5 Mar 2013

Chronic News and Research

Study evaluates patients with regional myocardial wall thinning

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

BIDMC investigator receives $50,000 CCF grant for research on pediatric cardiomyopathy

Primary Practice Physician Program for Chronic Pain and its impact on patients and providers

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

FDA accepts AMAG’s Feraheme sNDA for review

Drug to relieve pain of feline osteoarthritis identified

Pain self-management and exercise ‘effective in elderly’

UK’s health performance declining compared with 14 EU countries over past 20 years

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

New tool can help determine senior citizens' 10-year survivability rates

University of Manchester leads systems medicine research network for inflammatory bowel disease

Continuous dyskinesia monitoring technology for Parkinson’s to be developed by Great Lakes NeuroTechnologies

Benefits of diastolic function improvement in heart failure questioned

Omalizumab scratches the itch for urticaria patients

FES cycling associated with improvements in individuals with chronic spinal cord injury

Microcystins in drinking water

HIV might promote aging and disease progression in people with HCV, study results suggest

Cognitive behavioral therapy brings relief to people with diabetic neuropathies, researchers find

Oxidative stress turns protein that protects healthy cells into executioner: Study

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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