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Selcia's radiochemistry facility granted GMP certificate

Selcia Limited, a leading independent provider of Carbon-14 (C-14) radiolabelling services, is pleased to announce that its radiochemistry facility has been granted a Good Manufacturing Practice (GMP) certificate for the preparationand C-14 labellingofActive Pharmaceutical Ingredients (APIs)for clinical trials following a successful inspection by the UK's Medicines and Healthcare products Regulatory Agency (MHRA).

7 Dec 2010

Virally structured nano-electrodes boost energy capacity ten-fold

Viruses have a bad rep—and rightly so. The ability of a virus to quickly and precisely replicate itself makes it a destructive scourge to animals and plants alike. Now an interdisciplinary team of researchers at the University of Maryland's A. James Clark School of Engineering and College of Agriculture and Natural Resources, brought together by Professor Reza Ghodssi, is turning the tables, harnessing and exploiting the "self-renewing" and "self-assembling" properties of viruses for a higher purpose: to build a new generation of small, powerful and highly efficient batteries and fuel cells.

7 Dec 2010

Sequella files SQ109 IND for Phase 2 studies in H. pylori-related duodenal ulcers

Sequella, Inc., a clinical-stage company focused on commercializing novel drugs for treatment of infectious diseases, announced it has successfully filed an Investigational New Drug (IND) application with the U.S. Food & Drug Administration (FDA) to test SQ109 in patients suffering from H. pylori-related duodenal ulcers, and can now begin Phase 2 studies.

7 Dec 2010

Researchers develop new drugs to prevent post-traumatic stress syndrome

Post-traumatic stress syndrome - when a severely stressful event triggers exaggerated and chronic fear - affects nearly 8 million people in the United States and is hard to treat. In a preclinical study, Northwestern Medicine scientists have for the first time identified the molecular cause of the debilitating condition and prevented it from occurring by injecting calming drugs into the brain within five hours of a traumatic event.

7 Dec 2010

No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Investigators report no evidence of toxicity in the four hemophilia B patients enrolled to date in a gene therapy trial using a vector under development at St. Jude Children's Research Hospital and UCL (University College London) to correct the inherited bleeding disorder.

7 Dec 2010

Asuragen, Novartis to develop ARQ BCR-ABL1 RNA IS Calibrators, laboratory software reporting tools

Asuragen, Inc. announced today that it has entered into an exclusive agreement with Novartis to develop worldwide Armored RNA Quant BCR-ABL1 RNA International Scale Calibrators and laboratory software reporting tools, intended to aid laboratories with standardization of BCR-ABL1 RT-qPCR testing to the International Scale. As part of this agreement, Asuragen will develop and, if successful, distribute the ARQ BCR-ABL1 IS RNA Calibrators and software reporting tools to laboratories globally directly or through its distributors.

6 Dec 2010

Elsevier announces title change for Cancer Genetics and Cytogenetics journal

Elsevier, the world's leading publisher of scientific, technical and medical information, announced today that its highly respected Cancer Genetics and Cytogenetics journal is changing its title to Cancer Genetics and has named Dr. Jaclyn A. Biegel as editor-in-chief.

6 Dec 2010

$Updated Phase 1 study data of ponatinib in patients with refractory CML, Ph+ ALL presented at ASH$

Updated Phase 1 study data of ponatinib in patients with refractory CML, Ph+ ALL presented at ASH

ARIAD Pharmaceuticals, Inc. today announced updated clinical data from a fully enrolled and ongoing Phase 1 study of its investigational pan-BCR-ABL inhibitor, ponatinib, in patients with resistant and refractory chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia.

6 Dec 2010

MRI scans quantifies disruptions in blood brain barrier, identifies TBI patients at risk of developing PTE

Approximately 5 - 30% of patients with traumatic brain injury (TBI) develop post traumatic epilepsy (PTE). The onset of seizures in patients who are susceptible to PTE can range from weeks or months to more than a decade after TBI. In a presentation today at the 64th American Epilepsy Society annual meeting, scientists report that the analysis of routine MRI scans can reliably quantify the disruptions in the blood brain barrier that are increasingly believed to be a prominent contributor to epilepsy development.

6 Dec 2010

Study: REVLIMID and dexamethasone for high-risk smoldering multiple myeloma reduce risk of disease progression

Celgene International Sàrl (NASDAQ: CELG) announced that data evaluating combination therapy REVLIMID® (lenalidomide) and dexamethasone in patients with high-risk asymptomatic smoldering multiple myeloma were presented during the American Society of Hematology's annual meeting. The study reported REVLIMID and dexamethasone prolonged time to progression.

6 Dec 2010

Clinical data of PCI-32765 in patients with CLL presented at ASH Annual Meeting

Pharmacyclics, Inc. today announced data from three Chronic Lymphocytic Leukemia presentations at the American Society of Hematology Annual Meeting describing the Btk-selective inhibitor PCI-32765. Two presentations report preclinical data, and one presentation reports clinical data from a pooled analysis of 54 patients with CLL or Small Lymphocytic Lymphoma treated with PCI-32765.

6 Dec 2010

Seasonal light cycles can affect development of babies' specific brain function: Study

The season in which babies are born can have a dramatic and persistent effect on how their biological clocks function.

6 Dec 2010

Marine life-inspired anti-microbial surfaces

Taking a leaf from animals like dolphins and pilot whales that are known to have anti-fouling skins, researchers from A*STAR's Industrial Consortium On Nanoimprint (ICON) are using nanotechnology to create synthetic, chemical-free, anti-bacterial surfaces. The surfaces can reduce infections caused by pathogens such as S. aureus and E. coli and can be used on common plastics, medical devices, lenses and even ship hulls. Conventional methods for preventing bacterial surface attachment may use potentially harmful metal ions, nanoparticles, chemicals or UV-radiation.

5 Dec 2010

Multiple sclerosis therapy breakthrough with stem cells

There seems to a glimmer of hope for tens of thousands of multiple sclerosis sufferers as researchers discover a way to repair damaged nerves with stem cells. The British team says their findings could lead to the development of drugs that repair nerves in the brain and spinal cord and potentially reverse some of the symptoms of MS.

5 Dec 2010

Closer to restoring vision loss due to optic nerve damage

Damage to the optic nerve, connecting the eye with the brain, is a major cause of blindness. The most common culprit is glaucoma, estimated to affect more than 4 million Americans. There is currently no way to restore the lost vision, because the optic nerve, like other nerves in the mature central nervous system (CNS), cannot regenerate. Now, scientists at Children's Hospital Boston report achieving the greatest regeneration to date in the mammalian optic nerve.

4 Dec 2010

Exposure to nicotine during pregnancy may cause learning disabilities in children: Research

Exposure to nicotine during pregnancy leads to a decrease in adult stem cells and a change in synaptic plasticity in the hippocampus of the offspring, according to new research from the University of Alabama at Birmingham presented at Neuroscience 2010, the annual Society for Neuroscience meeting in San Diego in November.

4 Dec 2010

Gene mutation can lead to different mental illnesses when influenced by same environmental factor

Male mice born with a genetic mutation that's believed to make humans more susceptible to schizophrenia develop behaviors that mimic other major psychiatric illnesses when their mothers are exposed to an assault to the immune system while pregnant, according to new Johns Hopkins research.

4 Dec 2010

Key findings on plasma cell disorders to be presented at American Society of Hematology Annual Meeting

Caris Life Sciences, Inc., a leading biosciences company focused on enabling precise and personalized healthcare through the highest quality anatomic pathology, molecular profiling, and blood-based diagnostic services, announced that Dr. Raul Braylan, Hematopathologist and Clinical Medical Director of Hematopathology Services, will present key findings related to plasma cell disorders at the upcoming 52nd Annual Meeting and Exposition of the American Society of Hematology.

4 Dec 2010

Moderate consumption of 'energy drinks' can improve people's response time

Moderate consumption of so-called energy drinks can improve people's response time on a lab test measuring behavioral control, but those benefits disappear as people drink more of the beverage, according to a study published by the American Psychological Association.

3 Dec 2010

Prostate cancer imaging shows real-time tumor metabolism

A UCSF research collaboration with GE Healthcare has produced the first results in humans of a new technology that promises to rapidly assess the presence and aggressiveness of prostate tumors in real time, by imaging the tumor's metabolism.

3 Dec 2010

Laboratory News and Research

Selcia's radiochemistry facility granted GMP certificate

Virally structured nano-electrodes boost energy capacity ten-fold

Sequella files SQ109 IND for Phase 2 studies in H. pylori-related duodenal ulcers

Researchers develop new drugs to prevent post-traumatic stress syndrome

No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Asuragen, Novartis to develop ARQ BCR-ABL1 RNA IS Calibrators, laboratory software reporting tools

Elsevier announces title change for Cancer Genetics and Cytogenetics journal

Updated Phase 1 study data of ponatinib in patients with refractory CML, Ph+ ALL presented at ASH

MRI scans quantifies disruptions in blood brain barrier, identifies TBI patients at risk of developing PTE

Study: REVLIMID and dexamethasone for high-risk smoldering multiple myeloma reduce risk of disease progression

Clinical data of PCI-32765 in patients with CLL presented at ASH Annual Meeting

Seasonal light cycles can affect development of babies' specific brain function: Study

Marine life-inspired anti-microbial surfaces

Multiple sclerosis therapy breakthrough with stem cells

Closer to restoring vision loss due to optic nerve damage

Exposure to nicotine during pregnancy may cause learning disabilities in children: Research

Gene mutation can lead to different mental illnesses when influenced by same environmental factor

Key findings on plasma cell disorders to be presented at American Society of Hematology Annual Meeting

Moderate consumption of 'energy drinks' can improve people's response time

Prostate cancer imaging shows real-time tumor metabolism

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Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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