Cytokine News and Research

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Research unravels how cytokines prevent multi-organ damage during parasitic infection

Cytokines are proteins secreted by several types of immune cells in response to infection, inflammation, or injury. Interleukin-17 (IL-17) is one such cytokine that causes inflammation, by controlling the production of other cytokines and mobilizing a type of white blood cell (neutrophil) that fights infections.

3 Apr 2017

Research reveals dual role of TGF-beta cytokine in liver cancer

Recent research results from the TGF-beta and cancer research group at the Bellvitge Biomedical Research Institute, within IT-Liver, a collaborative European action among several research groups led by Dr. Isabel Fabregat, provide a better understanding of the role of the TGF-beta cytokine in liver cancer.

29 Mar 2017

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully developed a humanized mouse model showing that so-called NK cells that directly attacking tumors, can survive and maintain function in vivo.

28 Mar 2017

Review provides new understanding of cytokine mediated effects on inflammatory disorders

Researchers studying chronic inflammation that can lead to the development of lung diseases such as asthma, pulmonary fibrosis, and cancer, are focusing on the role cytokines play in regulating the behavior of fibroblast cells and the extracellular matrix.

24 Mar 2017

One-shot vaccine passes key preclinical test in newborn monkey models

Newborns are highly vulnerable to infections and don't respond optimally to most vaccines because their young immune systems typically mount weak antibody responses.

24 Mar 2017

Research findings hold promise to generate blood cell precursors from hPSCs

The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC).

21 Mar 2017

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options.

20 Mar 2017

MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs.

20 Mar 2017

Researchers discover new way to curb chronic pain

For millions of sufferers, there is nothing more debilitating than chronic back or joint pain. It can feel like a lifetime of misery.

14 Mar 2017

Inflammation acts as double-edge sword in regeneration, study reveals

Regeneration is an inherent property of life. However, the potential to regenerate differs across species: while fish and amphibians can re-grow appendages such as limbs, tails, and fins, mammals, including humans, cannot restore injured organs to their original shape and function.

7 Mar 2017

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

New research findings published in the Journal of Leukocyte Biology, suggest that synovial CD4+ T cells that produce IL-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients.

2 Mar 2017

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 - 400,000 people in Austria.

2 Mar 2017

Immune-stimulating chemical found in tumors may help stop cancer growth

A chemical found in tumors may help stop tumor growth, according to a new study.

2 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Scientists reveal how gluten plays role in development of rare form of cancer for coeliac patients

Scientists in The Netherlands have revealed how gluten plays a role in the development of a rare form of cancer, for some people with coeliac disease.

27 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

First breath of newborn shapes lifelong immunological milieu of lungs

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs every day and with this come numerous viruses, bacteria and pollutants, which need to be prevented from entering the body.

22 Feb 2017

Research may show new ways to repress inflammation at outset

Researchers at the University of Tübingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body.

21 Feb 2017

Baby’s sex linked to pregnant women's immune responses, study shows

Women have claimed for years that their bodies react differently whether they're pregnant with a male or female baby. Some studies suggest that a baby's sex could play a role in why some women report differences with morning sickness, cravings and other symptoms based on the sex of their baby.

10 Feb 2017

Penn scientists find cytokine as key to fighting and treating viral infection in the lungs

Viral infections that occur in a patient's lungs are a significant cause of hospitalization and death among children and the elderly.

3 Feb 2017

Cytokine News and Research

Research unravels how cytokines prevent multi-organ damage during parasitic infection

Research reveals dual role of TGF-beta cytokine in liver cancer

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Review provides new understanding of cytokine mediated effects on inflammatory disorders

One-shot vaccine passes key preclinical test in newborn monkey models

Research findings hold promise to generate blood cell precursors from hPSCs

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

Researchers discover new way to curb chronic pain

Inflammation acts as double-edge sword in regeneration, study reveals

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Immune-stimulating chemical found in tumors may help stop cancer growth

Using Spherical Nucleic Acids to Track and Treat Disease

Scientists reveal how gluten plays role in development of rare form of cancer for coeliac patients

Researchers discover promising target for treatment of leishmaniasis

First breath of newborn shapes lifelong immunological milieu of lungs

Research may show new ways to repress inflammation at outset

Baby’s sex linked to pregnant women's immune responses, study shows

Penn scientists find cytokine as key to fighting and treating viral infection in the lungs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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