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Iclusig gets FDA approval for two rare blood and bone marrow diseases

The U.S. Food and Drug Administration today approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases.

15 Dec 2012

Significant correlation between vitamin D and excessive daytime sleepiness

A new study suggests that there is a significant correlation between excessive daytime sleepiness and vitamin D, and race plays an important factor.

14 Dec 2012

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

The plague-causing bacteria Yersinia pestis evades detection and establishes a stronghold without setting off the body's early alarms.

14 Dec 2012

FDA grants accelerated approval to ARIAD’s Iclusig for treatment of CML, Ph+ ALL

ARIAD Pharmaceuticals, Inc. today announced that following a priority review, the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Iclusig (ponatinib) for the treatment of adult patients with chronic, accelerated or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor (TKI) therapy or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) that is resistant or intolerant to prior TKI therapy.

14 Dec 2012

Researchers question animal models that measure generalized anxiety disorder

Pre-clinical trials - the stage at which medications or therapies are tested on animals like laboratory mice - is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before a drug is administered to patients.

14 Dec 2012

Novel antibodies can aid in early diagnosis of Sjogren's Syndrome

Patients suffering from the painful autoimmune disease, Sjogren's Syndrome, will soon be able to be properly diagnosed much earlier, thanks to the discovery of novel antibodies by researchers at the University at Buffalo and Immco Diagnostics, Inc. The breakthrough, described in a paper in the December issue of Clinical Immunology, will allow patients to be treated sooner when they are much more likely to benefit.

14 Dec 2012

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Kentucky REC representatives receive top honors in Washington for health IT implementation

Representatives from the Kentucky Regional Extension Center (Kentucky REC), housed at the University of Kentucky College of Medicine, and the Kentucky Health Information Exchange (KHIE), part of the Kentucky Cabinet of Health and Family Services, received top honors in Washington, D.C. for exemplary work in health IT implementation.

14 Dec 2012

SLU researchers to study physiological and biochemical functions in lupus

Two researchers at Saint Louis University's division of rheumatology in the department of internal medicine have been awarded a $1.8 million NIH grant to study the physiological and biochemical functions in lupus, an autoimmune disease, and develop possible new medications for its treatment.

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the publication of data from its first-in-human Phase 1 study of its NDV-3 vaccine program in the journal Vaccine.

13 Dec 2012

Arginase, IDO could hold clues to help 79 million Americans with prediabetes

Two enzymes that are elevated in prediabetes could hold clues to helping the 79 million Americans with the condition avoid serious vascular complications and maybe even identify those most at risk for full-blown diabetes, researchers say.

13 Dec 2012

UCL scientists discover more than 200 gene locations for Crohn's disease

More than two hundred gene locations have now been identified for the chronic bowel condition Crohn's Disease, in a study that analysed the entire human genome.

13 Dec 2012

Modified eyelid surgery techniques reap rewards

Research suggests that modifying buried suture double-eyelid blepharoplasty may decrease the risk for complications and double-eyelid fold loss rate.

13 Dec 2012

LED light instantly triggers or reverses depression-like behavior in rodents

A specific pattern of neuronal firing in a brain reward circuit instantly rendered mice vulnerable to depression-like behavior induced by acute severe stress, a study supported by the National Institutes of Health has found. When researchers used a high-tech method to mimic the pattern, previously resilient mice instantly succumbed to a depression-like syndrome of social withdrawal and reduced pleasure-seeking - they avoided other animals and lost their sweet tooth.

13 Dec 2012

Doctors should use different therapies when treating older and younger patients with CLL

Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

13 Dec 2012

Medivir commences cohort 2 simeprevir and sofosbuvir phase II combination trial in HCV GT1

Medivir AB, announced today the initiation of cohort 2 in the interferon-free phase II trial combining simeprevir with sofosbuvir (GS7977) based on a safety and efficacy planned interim analysis of cohort 1 including prior null responder HCV genotype 1 infected patients without advanced hepatic fibrosis.

13 Dec 2012

Roadmap outlines steps that are necessary to improve healthcare delivery in the U.S.

Regardless of what you think about the Affordable Care Act (ACA), also called Obama Care, healthcare in the U.S. needs a major overhaul. That overhaul began with ACA, and now additional changes are going to be needed in order to make healthcare more economically sustainable in the U.S.

13 Dec 2012

ACS announces creation of Georgia Surgical Quality Collaborative

Today, the American College of Surgeons (ACS), in association with the American Cancer Society, hosted the ACS Surgical Health Care Quality Forum Georgia, the 11th program in a series of events to drive national discussions on effective quality improvement methods that surgeons, physicians and hospitals are using to improve patient safety and reduce costs.

13 Dec 2012

Chronic News and Research

Iclusig gets FDA approval for two rare blood and bone marrow diseases

Significant correlation between vitamin D and excessive daytime sleepiness

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

FDA grants accelerated approval to ARIAD’s Iclusig for treatment of CML, Ph+ ALL

Researchers question animal models that measure generalized anxiety disorder

Novel antibodies can aid in early diagnosis of Sjogren's Syndrome

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Kentucky REC representatives receive top honors in Washington for health IT implementation

SLU researchers to study physiological and biochemical functions in lupus

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

Arginase, IDO could hold clues to help 79 million Americans with prediabetes

UCL scientists discover more than 200 gene locations for Crohn's disease

Modified eyelid surgery techniques reap rewards

LED light instantly triggers or reverses depression-like behavior in rodents

Doctors should use different therapies when treating older and younger patients with CLL

Medivir commences cohort 2 simeprevir and sofosbuvir phase II combination trial in HCV GT1

Roadmap outlines steps that are necessary to improve healthcare delivery in the U.S.

ACS announces creation of Georgia Surgical Quality Collaborative

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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