Laboratory News and Research

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Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

A tiny, translucent zebrafish that glows green when its liver makes glucose has helped an international team of researchers identify a compound that regulates whole-body metabolism and appears to protect obese mice from signs of metabolic disorders.

2 Dec 2012

Researchers uncover molecular structure of master regulator central to melanoma

With the X-ray vision of DESY's light source DORIS, a research team from Hamburg and Iceland has uncovered the molecular structure of a master regulator central to the most deadly form of skin cancer, melanoma.

1 Dec 2012

Scientists can produce new proteins by following certain rules

By following certain rules, scientists can prepare architectural plans for building ideal protein molecules not found in the real world. Based on these computer renditions, previously non-existent proteins can be produced from scratch in the lab. The principles to make this happen appear this month in Nature magazine.

1 Dec 2012

Researchers study antimicrobial peptides in fish gills to find solution for blocking human infections

Living in an environment teaming with bacteria and fungi, fish have evolved powerful defenses against waterborne pathogens, including antimicrobial peptides located in their gills. Undergraduate researchers at Worcester Polytechnic Institute are studying the biology and the mechanics of one of those peptides with the hope they can use that knowledge to create engineered surfaces that kill bacteria responsible for foodborne illnesses and hospital-acquired infections.

1 Dec 2012

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Researchers in the Nutritional Immunology and Molecular Medicine Laboratory at Virginia Bioinformatics Institute have discovered how a common diarrhea-causing bacterium sends the body's natural defenses into overdrive, actually intensifying illness while fighting infection.

1 Dec 2012

Reduced production of myelin may play role in development of mental illness: Study

Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to researchers at the Graduate School of Biomedical Sciences at Mount Sinai School of Medicine.

1 Dec 2012

Study of hospital-acquired infection yields potential therapeutic target

30 Nov 2012

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings

Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective peptides, according to researchers at the National Institutes of Health.

30 Nov 2012

Mistletoe extract plays a vital role in treating colon cancer

Mistletoe has become an important symbol of Christmas but it also has the potential to play a vital role as an alternative therapy for sufferers of colon cancer.

30 Nov 2012

Medically unexplained symptoms cause relevant annual excess costs in health care

This study highlights that medically unexplained symptoms cause relevant annual excess costs in health care that are comparable to mental health problems like depression or anxiety disorders and which may be reduced by interventions targeting physicians as well as patients. More extensive research on indirect costs and cost-effectiveness is needed.

30 Nov 2012

December issue of Neurosurgical Focus explores sports-related concussions

The JNS Publishing Group is pleased to announce that the December issue of Neurosurgical Focus is dedicated to Concussion: Pathophysiology & Sequelae.

30 Nov 2012

Membrane-proximal external region of HIV could be used to design vaccines

Beatriz Apellaniz, PhD holder of the UPV/EHU-University of the Basque Country, has studied in her PhD thesis HIV regions that could be used to design a vaccine. The researcher has focussed her research on a specific region of the surface protein of the Human Immunodeficiency Virus (HIV), which is responsible for the Autoimmune Deficiency Syndrome (AIDS), one of the diseases with the greatest human morbidity and mortality.

30 Nov 2012

Home Access Health urges individuals at risk for HIV infection to get tested

Home Access Health Corporation, America's leading provider of at-home HIV tests, today recognized World Aids Day Saturday by urging individuals at risk for HIV infection to get tested.

30 Nov 2012

Primitive human stem cells resistant to human cytomegalovirus

A new study published online in PLOS ONE reveals that primitive human stem cells are resistant to human cytomegalovirus (HCMV), one of the leading prenatal causes of congenital intellectual disability, deafness and deformities worldwide.

30 Nov 2012

Two Sanford-Burnham projects win International Space Station Research Competition

Sanford-Burnham Medical Research Institute (Sanford-Burnham) today announced that two of the Institute's research teams have won Space Florida's International Space Station (ISS) Research Competition. Eight teams were selected from a pool of international applicants to send experiments to space in late 2013.

30 Nov 2012

Fn14 gene plays a role in growth and spread of non-small cell lung cancer tumors

Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options.

30 Nov 2012

Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).

29 Nov 2012

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

In November 2006, when Clara Marshall began suffering from the effects of dementia, her family moved her into ... an assisted living home in Vancouver, Wash. ... just five months into her stay, Ms. Marshall, 81, was found dead in her room apparently strangled after getting her neck caught in side rails used to prevent her from rolling out of bed.

29 Nov 2012

Combination of blood test and whole-genome sequencing technology could screen cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

29 Nov 2012

Laboratory News and Research

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

Researchers uncover molecular structure of master regulator central to melanoma

Scientists can produce new proteins by following certain rules

Researchers study antimicrobial peptides in fish gills to find solution for blocking human infections

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Reduced production of myelin may play role in development of mental illness: Study

Study of hospital-acquired infection yields potential therapeutic target

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings

Mistletoe extract plays a vital role in treating colon cancer

Medically unexplained symptoms cause relevant annual excess costs in health care

December issue of Neurosurgical Focus explores sports-related concussions

Membrane-proximal external region of HIV could be used to design vaccines

Home Access Health urges individuals at risk for HIV infection to get tested

Primitive human stem cells resistant to human cytomegalovirus

Two Sanford-Burnham projects win International Space Station Research Competition

Fn14 gene plays a role in growth and spread of non-small cell lung cancer tumors

Scientists define key underlying process implicated in multiple sclerosis

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

Combination of blood test and whole-genome sequencing technology could screen cancers

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