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Common blood signals explain why chronic diseases cluster as we age

This population-based study shows that shared and pattern-specific blood biomarkers reflect biological vulnerability underlying multimorbidity and the pace at which chronic diseases accumulate in older adults. Metabolic and systemic stress markers such as GDF15, HbA1c, cystatin C, and insulin consistently tracked higher disease burden and faster accumulation, with findings replicated across cohorts.

5 Jan 2026

Injectable paste from human skin cells may improve breast reconstruction

Removing part or all of the breast during breast cancer treatment is a potential outcome for some people.

5 Jan 2026

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched a randomized phase III clinical trial called RECIPROCAL (Alliance A032304) to explore whether doctors can optimize the timing of targeted radiation therapy to minimize side effects while preserving efficacy in men with advanced prostate cancer.

5 Jan 2026

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.

5 Jan 2026

To knock down health-system hurdles between you and HIV prevention, try these 6 things

A couple of years ago, Matthew Hurley got the kind of text people fear.

5 Jan 2026

Weaker and fragmented circadian rhythms linked to higher dementia risk

Circadian rhythms that are weaker and more fragmented are linked to an increased risk of dementia, according to a new study published on December 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

4 Jan 2026

New method can help better assess precision genome editing technology

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources spent improving CRISPR gene editing technology focus on identifying small off-target sites that pose a safety risk, which is also technically challenging.

2 Jan 2026

Elevated bacteria levels in tumors weaken immune response, studies show

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

2 Jan 2026

New therapeutic approach converts immune cells inside tumors into anticancer cell therapies

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.

2 Jan 2026

Newly identified rare genetic variant reduces the risk of leukemia

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia.

2 Jan 2026

Advertisements promising patients a ‘dream body’ with minimal risk get little scrutiny

Lenia Watson-Burton, a 37-year-old U.S. Navy administrator, expected that cosmetic surgery would get rid of stubborn fat quickly and easily — just as the web advertising promised.

1 Jan 2026

Label-free polarized light reveals subtle red blood cell deformations

Red blood cells are essential for oxygen transport and immune function in the human body. When these cells become abnormally shaped, they can indicate serious health conditions, including diabetes, malaria, hereditary blood disorders, and vascular diseases.

1 Jan 2026

Small shifts in blood sodium may influence human brain excitability

This exploratory study in healthy young adults found that plasma sodium levels within the normal clinical range are significantly associated with resting motor threshold, an indirect measure of corticospinal excitability. Lower sodium concentrations were linked to lower thresholds, suggesting subtle physiological variation in electrolytes may relate to interindividual differences in brain excitability.

1 Jan 2026

Novel method can generate functional organoids from human adult adipose tissue

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

30 Dec 2025

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Minimal residual disease monitoring can transform breast cancer care

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

30 Dec 2025

Immune cell energy metabolism shapes the progression of atherosclerosis

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

30 Dec 2025

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

30 Dec 2025

New roadmap guides antiseizure medication adjustments during pregnancy and postpartum

For the first time, clinicians have access to a clear, evidence-based roadmap for adjusting antiseizure medication doses during pregnancy and after childbirth.

30 Dec 2025