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ALN RNAi therapeutic program represents novel approach for treatment of AAT deficiency

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data with an RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of liver disease associated with AAT deficiency. These data were presented at the 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD, "The Liver Meeting") held November 9-13, 2012 in Boston.

15 Nov 2012

Potential diagnostic method to identify subset of patients with chronic fatigue syndrome

For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome (CFS), a complex disorder with no known definitive cause or cure.

15 Nov 2012

Obesity and dental cavities increase and become epidemic as homeless children age

Obesity and dental cavities increase and become epidemic as children living below the poverty level age, according to nurse researchers from the Case Western Reserve University and the University of Akron.

14 Nov 2012

Exposure to uranium may increase lupus rates

People living near a former uranium ore processing facility in Ohio are experiencing a higher than average rate of lupus, according a new study conducted by scientists at the University of Cincinnati and Cincinnati Children's Hospital Medical Center.

14 Nov 2012

Study indicates that impact of early-life abuse extend well into older age

The psychological scars of childhood abuse can last well into adulthood. New research from Concordia University shows the harm can have longterm negative physical effects, as well as emotional ones.

14 Nov 2012

Neuroticism can be good for health under certain circumstances

Under certain circumstances neuroticism can be good for your health, according to a University of Rochester Medical Center study showing that some self-described neurotics also tended to have the lowest levels of Interleukin 6 (IL-6), a biomarker for inflammation and chronic disease.

14 Nov 2012

Blood flow, temperature, reveal relationship between dental implants and healthy teeth

Blood flow in the tissue surrounding dental implants is reduced compared with that found around adjacent natural teeth, and the surface temperature of this implant-associated tissue is higher, show study results.

13 Nov 2012

Calcium-related hormone could help identify pneumonia

Serum procalcitonin measurements could improve the accuracy of pneumonia diagnoses when chest radiographs give indeterminate results, indicate US study findings.

12 Nov 2012

Weight-based ribavirin undertreats African–American HCV patients

African–Americans with hepatitis C virus genotype 1 infections have lower ribavirin plasma exposures than Caucasian Americans when treated with weight-based ribavirin plus peginterferon.

12 Nov 2012

Multivitamin disappoints in first long-term CV trial

Taking a daily multivitamin does not reduce the risk for major cardiovascular events or mortality in men, research suggests.

9 Nov 2012

OSA treatment reduces office blood pressure

Treatment of obstructive sleep apnea can reduce blood pressure in men with hypertension, a clinical practice study has shown.

9 Nov 2012

Metabolic syndrome linked to poorer cognition in schizophrenia

Schizophrenia patients with the metabolic syndrome have poorer cognitive functioning than those without, results from a US study show.

9 Nov 2012

Reminder of values helps African–Americans interact with physicians

Completing a values-affirmation task before a scheduled visit to the primary care physician could improve communications between African–American patients and their providers, show the results of a randomized, controlled study.

9 Nov 2012

Elevated ST2 biomarker levels strongly indicate heart failure and mortality in HIV patients

Critical Diagnostics, makers of the Presage ST2 Assay, announced today that during a presentation at the American Heart Association Scientific Sessions in Los Angeles, the results of a study demonstrated that elevated levels of the biomarker ST2 in HIV patients was strongly indicative of the development of heart failure and mortality.

9 Nov 2012

Regenstrief Institute and Merck sign five-year collaboration agreement

The Regenstrief Institute and Merck, known as MSD outside the United States and Canada, have signed a five-year agreement to collaborate on a range of projects that will use clinical data to inform personalized delivery of health care.

9 Nov 2012

SCCA to raise awareness about importance of lung cancer screening

Lung cancer is the No. 1 cause of cancer deaths in the United States, despite the fact it is largely preventable. For people at high risk of developing lung cancer, such as current or former longtime smokers, screening for the disease with low-dose CT scans is now a viable option that has been shown to significantly reduce mortality rates. In conjunction with National Lung Cancer Awareness Month, Seattle Cancer Care Alliance (SCCA) wants to raise awareness about the importance of prevention and early detection for at-risk populations.

9 Nov 2012

Avinger receives FDA clearance for Ocelot System

Avinger, Inc., a medical device manufacturer of innovative, multi-functional catheters for crossing chronic total occlusions (CTOs) in patients with Peripheral Artery Disease (PAD), announces its Ocelot System has been cleared for sale in the U.S. by the Food and Drug Administration (FDA).

9 Nov 2012