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Urine-based microRNA clock predicts biological aging without a blood test

Researchers developed and validated a non-invasive urinary microRNA aging clock using extracellular vesicle miRNAs from more than 6,000 adults. The model predicts age with about 4 to 5 years error and links accelerated aging signals to type 2 diabetes.

16 Dec 2025

Multiple biological systems show abnormalities in ME/CFS patients

New Australian research has identified simultaneous abnormalities across multiple biological systems in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

16 Dec 2025

Specific gut bacterium reduces weight gain and improves metabolic health

The gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.

16 Dec 2025

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

16 Dec 2025

New diagnostic chip enables rapid monitoring of brain cancer treatment

New diagnostic chip pulls packets released from tumor cells out of blood, showing whether cancer cells died during chemotherapy infusion.

16 Dec 2025

New rapid blood test enables early and accurate diagnosis of ALS

ALS is a debilitating paralytic disease characterized by the death of upper and lower motor neurons. Fortunately, ALS is relatively rare, with an incidence rate of 1.6 per 100,000 adults, resulting in about 30,000 cases in the United States at any one time.

16 Dec 2025

AI enables rapid detection of coronary microvascular dysfunction from standard EKGs

Doctors may soon be able to diagnose an elusive form of heart disease within seconds by using an AI model developed at University of Michigan, according to a recent study.

16 Dec 2025

Pathology AI models show demographic bias in cancer diagnosis

Pathology has long been the cornerstone of cancer diagnosis and treatment. A pathologist carefully examines an ultrathin slice of human tissue under a microscope for clues that indicate the presence, type, and stage of cancer.

16 Dec 2025

Revolutionary quantum sensors could enable earlier cancer diagnosis and treatment

A revolutionary quantum sensing project that could transform cancer treatment by tracking how immune cells interact with tumors has been awarded a prestigious £2 million Future Leaders Fellowship.

16 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

Injury burden is higher during menstruation in professional female footballers

The menstrual cycle is a key physiological process in women: it impacts performance, neuromuscular control, metabolism, and immune response.

16 Dec 2025

New data supports link between gum disease and heart disease

There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective prevention and treatment of gum disease, also called periodontal disease, could potentially decrease the burden of cardiovascular disease, according to a new scientific statement published today in the American Heart Association's flagship journal Circulation.

16 Dec 2025

Combining stem cell therapy and BDNF enhancement to manage Parkinson’s disease

Parkinson's disease (PD) is an age-related, progressive, neurodegenerative condition, caused by loss of dopamine-producing neurons.

16 Dec 2025

Study identifies molecular drivers of cerebral small vessel disease

A new study identifies molecular factors that promote small vessel disease - and an active drug that can restore impaired vascular functions.

16 Dec 2025

Functional MRI signals can misrepresent true brain activity

Researchers at the Technical University of Munich (TUM) and the Friedrich-Alexander-University Erlangen-Nuremberg (FAU) found that an increased fMRI signal is associated with reduced brain activity in around 40 percent of cases.

16 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

High fructose intake increases fatty liver risk

Excessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.

16 Dec 2025

One big beautiful bill act complicates state health care affordability efforts

As Congress debates whether to extend the temporary federal subsidies that have helped millions of Americans buy health coverage, a crucial underlying reality is sometimes overlooked: Those subsidies are merely a band-aid covering the often unaffordable cost of health care.

16 Dec 2025

Mediterranean diet and healthy habits improve cancer survival rates

Being more physically active, following a balanced diet, not smoking, and keeping body weight and blood pressure under control: the same habits that protect the heart also prove decisive after a cancer diagnosis.

16 Dec 2025