Chronic News and Research

RSS

New data shows consolidation of interferon-free revolution in HCV treatment

New data presented at the International Liver Congress 2012 shows consolidation of the interferon-free (IFN) revolution in HCV treatment. The much anticipated data from a number of clinical trials confirm that combinations of antivirals offer the hope of shorter, more effective treatment with fewer side effects.

20 Apr 2012

Longer looks: Rushed medicine; Exercising your way to a smarter brain

Something in the world of medicine is seriously amiss. Unhappy patients gripe about their doctors' brusque manner and give them bad marks on surveys and consumer websites like HealthGrades and Angie's List. They tell tales of being rushed out of the office by harried doctors who miss crucial diagnoses, never look up from their computers during an exam, make errors in prescriptions, and just plain don't listen to their patients. ... And things don't seem much better from the other side of the stethoscope.

20 Apr 2012

Roundup: State spending drops $290 billion in 5 years; Emory hospital loses data on 315,000 patients

News outlets examine a variety of state health policy issues, including articles from California, Colorado, Florida, Georgia, Kansas, Louisiana, Maine, Massachusetts, New Hampshire and Oregon.

20 Apr 2012

Mood disorders not linked to nasal obstruction

While mood disorders like depression or anxiety tend to negatively affect treatment for allergies and chronic rhinosinusitis, the same cannot be said for patients with nasal obstructions such as deviated septum, according to researchers at Henry Ford Hospital.

20 Apr 2012

Rare CARD14 gene mutations can lead to plaque psoriasis

Scientists led by Washington University School of Medicine in St. Louis have identified the first gene directly linked to the most common form of psoriasis, a chronic skin condition.

20 Apr 2012

Therapeutic hypothermia reduces in-hospital deaths among sudden cardiac arrest patients

Forced body cooling known as therapeutic hypothermia has reduced in-hospital deaths among sudden cardiac arrest patients nearly 12 percent between 2001 and 2009, according to a Mayo Clinic study being presented at the upcoming American Academy of Neurology 2012 Annual Meeting in New Orleans.

20 Apr 2012

ACS report outlines gaps and opportunities that contribute to cancer mortality

An annual report from the American Cancer Society says much of the suffering and death from cancer could be prevented by more systematic efforts to reduce tobacco use, improve diet and physical activity, reduce obesity, and expand the use of established screening tests. The report, Cancer Prevention and Early Detection Facts and Figures (CPED), outlines gaps and opportunities that contribute to cancer mortality, and says social, economic, and legislative factors profoundly influence individual health behaviors.

20 Apr 2012

Final results from MSD’s VICTRELIS plus PEGINTRON Phase III trial on HCV treatment-related anemia

MSD, known as Merck in the United States and Canada, announced final results from a Phase III, open-label study designed to compare the impact of two anaemia management strategies on sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) genotype 1 infection treated with VICTRELIS(boceprevir) in combination with PEGINTRON and ribavirin.

20 Apr 2012

NALFD patients with modest alcohol intake are half as likely to develop NASH

People with nonalcoholic fatty liver disease (NALFD) who consume alcohol in modest amounts - no more than one or two servings per day - are half as likely to develop hepatitis as non-drinkers with the same condition, reports a national team of scientists led by researchers at the University of California, San Diego School of Medicine.

20 Apr 2012

HDAC9 gene can lead to obesity-induced body fat dysfunction

Cardiac researchers at the University of Cincinnati (UC) have found that a certain cellular pathway is linked to obesity-related disorders, like diabetes, heart disease and fatty liver disease.

20 Apr 2012

Even a little physical activity a day keeps Alzheimer’s away

It is estimated that by 2030, the number of people with Alzheimer's disease worldwide is expected to double to 80 million. A new study shows a ray of hope. It found that daily physical activity might provide a person's best chances of staving off the degenerative brain disorder - even if they're over 80 years old.Additionally exercise does not have to be strenuous. Activities such as cooking and cleaning also led to a protective benefit.

19 Apr 2012

Study demonstrates far-reaching impact of voice disorders

Patients with voice problems have nearly as many days of short-term disability claim and work productivity losses as those with chronic conditions like asthma, heart disease and depression, according to new findings from Duke University Medical Center researchers. Per claim, voice disorders account for up to 40 lost workdays and about $3,400 in short-term disability payments annually.

19 Apr 2012

Soldiers, farmers can have common chronic exposure to nerve impacting chemicals

Soldiers in war zones and farmers tending their fields can have in common chronic exposure to chemicals that impact their nerves.

19 Apr 2012

EASL publishes new clinical practice guideline on ALD

EASL today announced the publication of a new clinical practice guideline (CPG) in the area of Alcoholic Liver Disease (ALD), bringing the number of CPGs published to date to eight.

19 Apr 2012

Two studies show true impact of liver disease across Europe

Two studies presented at the International Liver Congress- 2012 show the true impact that liver disease has across Europe. One highlights the financial cost of liver disease to the community and the second highlights the high mortality rates associated with cirrhosis.

19 Apr 2012

Final data from Santaris’ miravirsen Phase 2a trial on HCV to be presented at ILC 2012

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, will present final data from a Phase 2a trial showing that miravirsen given as a four-week monotherapy treatment provided robust dose-dependent anti-viral activity with a mean reduction of 2 to 3 logs from baseline in HCV RNA (log10 IU/mL) that was sustained well beyond the end of therapy.

19 Apr 2012

Researchers describe how they combine two pieces of technology to create neuroprosthesis

An artificial connection between the brain and muscles can restore complex hand movements in monkeys following paralysis, according to a study funded by the National Institutes of Health.

19 Apr 2012

Bristol-Myers Squibb, Janssen expand TMC435, BMS-986094 clinical collaboration agreement

Medivir AB, the research-based speciality pharmaceutical company focused on the development of high-value treatments for infectious diseases, announces that its development partner, Janssen R&D Ireland has broadened its clinical collaboration agreement with Bristol-Myers Squibb Company.

19 Apr 2012

Regular physical activity may decrease risk of AD even in very old adults

Daily physical activity may reduce the risk of Alzheimer's disease and cognitive decline, even in people over the age of 80, according to a new study by neurological researchers from Rush University Medical Center that will be published in the online issue of Neurology, the medical journal of the American Academy of Neurology on April 18.

19 Apr 2012

CRF announces top 10 clinical research achievement awards

Ten outstanding clinical research projects from institutions around the country have been selected to receive the inaugural Clinical Research Forum Top 10 Clinical Research Achievement Awards. The winning projects are compelling examples of the scientific innovation that results from the nation's investment in clinical research that can benefit human health and welfare.

19 Apr 2012