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ChemoCentryx fourth quarter revenues increase to $26.1 million

ChemoCentryx, Inc. announced today its financial results for the fourth quarter and year ended December 31, 2011.

31 Mar 2012

Physicians advised to use caution in prescribing sedatives for patients taking opioids

Adverse events associated with taking opioid pain medications increase in patients who concurrently use sedatives and alcohol. A study in The Journal of Pain, published by the American Pain Society, advises physicians to use caution in prescribing sedatives for patients taking opioids, even if there is no history of substance abuse.

30 Mar 2012

Cancer cells grow and proliferate more robustly when exposed to human cells

New research from the Technion-Israel Institute of Technology Rappaport Faculty of Medicine and Research Institute and the Rambam Medical Center may lead to the development of new methods for controlling the growth of cancer, and perhaps lead to treatments that will transform cancer from a lethal disease to a chronic, manageable one, similar to AIDS.

30 Mar 2012

Ozone can trigger severe violent breathing attacks in many people

Ozone, the prevalent gas found in air pollution, and mostly experienced from March to October, can trigger severe violent breathing attacks in many people, particularly children and seniors, says a lung expert from Ben Taub General Hospital in Houston.

30 Mar 2012

Who was who during the Supreme Court arguments?

News outlets take a look at key personalities on the bench, in front of the justices, in the gallery and in the creation of the health law itself -- including examinations of the closing arguments by both the plantiffs' attorney and the federal government's lawyer.

30 Mar 2012

Health workers feeling effects of staff, supply shortages at clinics in southwestern Uganda

Health workers with Medical Teams International, a medical non-governmental organization, "say they are overwhelmed" by high demand at five health clinics in two southwestern Ugandan refugee centers, PlusNews reports.

30 Mar 2012

OMRF researchers identify three lupus genes

Three newly confirmed lupus genes are opening new avenues of research at the Oklahoma Medical Research Foundation.

30 Mar 2012

Researchers discover MicroRNAs as new switch of adipose cell development

Hunger has always threatened mankind. This makes it unsurprising that human bodies attempt to store all surplus nourishment in adipose tissue. In developed countries, this life-saving craving is turning into a problem and obesity—adiposity—is turning into a danger. Why, though, does excess fat the body ill? How does fat trigger diabetes? And can these superfluous fat reserves be turned into warmth and just as well burnt?

30 Mar 2012

Study explains how rapamycin also causes insulin resistance

A Penn- and MIT-led team explained how rapamycin, a drug that extends mouse lifespan, also causes insulin resistance. The researchers showed in an animal model that they could, in principle, separate the effects, which depend on inhibiting two protein complexes, mTORC1 and mTORC2, respectively.

30 Mar 2012

Cancer death rates declining but obesity still needs to be tackled

According to a new report from four major national cancer tracking groups there has been a steady decline in cancer death rates for men, women and children from 2004 to 2008. The declines in death and new cases of cancer reflect progress against the disease in terms of prevention, diagnosis and treatment, but experts say rising obesity may present a new challenge in the fight against cancer.

29 Mar 2012

Lilly's ixekizumab Phase II trial on plaque psoriasis meets primary endpoint

New Phase II data, published today in the New England Journal of Medicine, showed that Eli Lilly and Company's ixekizumab, an anti-IL-17 monoclonal antibody, met its primary endpoint in patients with moderate-to-severe plaque psoriasis, with significantly more patients achieving at least a 75 percent improvement in Psoriasis Area and Severity Index (PASI) scores from baseline (PASI 75) compared with placebo at week 12.

29 Mar 2012

State roundup: Georgia's child-only insurance policies; N.Y. exchange impasse

The Senate's Republican majority refused to agree to create a "health exchange," or state-based health insurance market required under President Barack Obama's health care overhaul, for individuals and small businesses to insure more Americans.

29 Mar 2012

Positive results from Nile's cenderitide Phase 1 trial on chronic heart failure

Nile Therapeutics, Inc., a biopharmaceutical company that develops novel therapeutics for heart failure patients, today announced results from its recently completed Phase 1 clinical trial evaluating the pharmacokinetics (PK), pharmacodynamics (PD), safety and tolerability of subcutaneous bolus and subcutaneous infusion of cenderitide in patients with chronic heart failure.

29 Mar 2012

FDA extends review period for Almirall and Forest Labs' aclidinium bromide NDA

Forest Laboratories, Inc. and Almirall, S.A. announced today that the U.S. Food and Drug Administration (FDA) will require a three-month extension to complete its review of the data supporting the New Drug Application (NDA) for aclidinium bromide, a new long-acting antimuscarinic for the maintenance treatment of Chronic Obstructive Pulmonary Disease.

29 Mar 2012

SafeStitch Medical's AMID Stapler to be presented at AHS 2012

SafeStitch Medical, Inc. will present the AMID Stapler® at the 5th International Hernia Congress in New York City, March 28-31, 2012.

29 Mar 2012

Daiichi Sankyo, NGM to discover and develop new treatments for diabetes

Daiichi Sankyo Company, Ltd. and NGM Biopharmaceuticals, Inc. announced today that they have entered into a research collaboration and license agreement to discover and develop novel therapeutics that modulate beta-cell regeneration for the treatment of diabetes.

29 Mar 2012

Obstacles standing in the way of cancer prevention

More than half of all cancer is preventable, and society has the knowledge to act on this information today, according to Washington University public health researchers at the Siteman Cancer Center in St. Louis.

29 Mar 2012

Change in registry protocols leads to underreporting of myeloid malignancies

Researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues from the UF Shands Cancer Center in Gainesville, Fla., have found that cases of myeloid malignancies are being underreported since a change in registry protocols and laboratory practices starting in 2001.

29 Mar 2012

DaVita thanks nearly 1,500 renal social workers during NASW

DaVita Inc., a leading provider of kidney care services that is committed to improving the quality of life for those diagnosed with chronic kidney disease (CKD), today thanks its nearly 1,500 social workers for the value and care they provide to patients and their families.

29 Mar 2012

Althea provides Allena exclusive worldwide rights to broad hyperoxaluria portfolio

Allena Pharmaceuticals, Inc., and Althea Technologies today announced a licensing agreement under which Allena has obtained the exclusive worldwide rights to Althea's broad hyperoxaluria portfolio including product patents, regulatory information and development data related to oxalate degrading enzymes.

29 Mar 2012