Cell News and Research

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How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver.

4 Mar 2020

Novel compounds show promise as potent new treatment for malaria

A novel class of antimalarial compounds that can effectively kill malaria parasites has been developed by Australian and US researchers.

4 Mar 2020

New repair mechanism for alcohol-induced DNA damage discovered

Researchers of the Hubrecht Institute in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol.

4 Mar 2020

New experimental platform for cancer diagnostics, prognoses and testing drugs

Parts of tumor tissue, which is normally discarded in cancer surgery, bear information about the disease. So far, as studies at the University of Gothenburg show, this has been unexploited.

4 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

A new, promising method for developing drugs that target, block macropinocytosis

With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle.

3 Mar 2020

New UCLA study reveals mechanism underlying breathing rhythm generation

Breathing propels everything we do--so its rhythm must be carefully organized by our brain cells, right?

3 Mar 2020

Chemists develop promising molecular tool to target cell immortality's underlying gears

One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: the enzyme telomerase.

3 Mar 2020

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Desperate times need desperate measures. Accordingly, scientists, today published a new study in the journal Cell Host and Microbe in March 2020, showing that drugs that prevent the acquisition of DNA-borne antibiotic resistance traits from their surroundings by bacteria can stop mice from becoming resistant to the action of the antibiotics.

3 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

Observation of telomerase activity at a single-molecule level using 'optical tweezers'

Stem cells involved in replenishing human tissues and blood depend on an enzyme known as telomerase to continue working throughout our lives. When telomerase malfunctions, it can lead to both cancer and premature aging conditions.

3 Mar 2020

Researchers establish a gene expression profile associated with cachexia in cancer patients

It is estimated that as many as 80% of advanced-stage cancer patients may develop cachexia, a potentially fatal metabolic syndrome characterized by extreme weight loss and muscle wasting, but scientists do not yet fully understand why it is more frequently associated with certain kinds of tumor than others, or why not all cancer patients develop it.

3 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Boosting energy levels within damaged nerve fibers may promote axonal regeneration

Each year, thousands of people in the United States experience a spinal cord injury, damaging the system of nerves that the brain and body use to communicate.

3 Mar 2020

Study reveals the mechanisms in our brains that lead to satiety after a meal

You just finished a good meal and are feeling full? Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm, and University of Luxembourg have just revealed the mechanisms in our brains that lead to this state.

3 Mar 2020

New method maps 3D forces exerted by tiny cell clusters

A team of researchers has developed a new technique to map the three-dimensional forces that clusters of human cells exert on their surrounding environment. The method could potentially help scientists better understand how tissue forms, how wounds heal or how tumors spread.

3 Mar 2020

Research opens up new prospects for prevention and treatment of bacterial pneumonia

Researchers from the Lille Centre for Infection and Immunity, INRAE and from Brazilian (Belo Horizonte), Scottish (Glasgow) and Danish (Copenhagen) laboratories have shown for the first time in mice that perturbation of the gut microbiota caused by the influenza virus favors secondary bacterial superinfection.

3 Mar 2020

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

Researchers detect a novel cause of acquired lipodystrophy

Nonalcoholic fatty liver disease (NAFLD) is mostly diagnosed in overweight and obese people. However, severe forms of NAFLD can also be detected in rare genetic diseases such as lipodystrophy or in patients with HIV, putting them at a high risk for developing liver failure, diabetes and cardiovascular diseases.

3 Mar 2020

Cell News and Research

How do cells protect themselves from viruses?

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Novel compounds show promise as potent new treatment for malaria

New repair mechanism for alcohol-induced DNA damage discovered

New experimental platform for cancer diagnostics, prognoses and testing drugs

Antidepressant shows promise in helping men with recurrent prostate cancer

A new, promising method for developing drugs that target, block macropinocytosis

New UCLA study reveals mechanism underlying breathing rhythm generation

Chemists develop promising molecular tool to target cell immortality's underlying gears

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

Observation of telomerase activity at a single-molecule level using 'optical tweezers'

Researchers establish a gene expression profile associated with cachexia in cancer patients

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Boosting energy levels within damaged nerve fibers may promote axonal regeneration

Study reveals the mechanisms in our brains that lead to satiety after a meal

New method maps 3D forces exerted by tiny cell clusters

Research opens up new prospects for prevention and treatment of bacterial pneumonia

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Researchers detect a novel cause of acquired lipodystrophy

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