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Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Patients with autoimmune diseases like multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis have an imbalance between two types of immune system T cells.

26 Feb 2020

Breakthrough research may lead to improved therapeutic options for people with asthma

Researchers from Trinity College Dublin have made a breakthrough that may eventually lead to improved therapeutic options for people living with asthma.

26 Feb 2020

Stem cell discovery could open the door to new approach for bone marrow transplantation

Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study being published on February 27 in Cell Stem Cell.

26 Feb 2020

Study sheds new light on the immune system’s ability to deal with co-infection

The body’s immune response to fungal infections changes when a patient is also infected by a virus, according to new research which investigated the two types of infection together for the first time.

26 Feb 2020

Gene-editing is more error-prone than thought, new findings suggest

The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences.

26 Feb 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.

25 Feb 2020

Targeting overactive immune cells with experimental drug could improve TBI symptoms

Researchers at the University of Maryland School of Medicine found that targeting overactive immune cells in the brain with an experimental drug could limit brain cell loss and reverse cognitive and motor difficulties caused by traumatic brain injury.

25 Feb 2020

Scientists discover new biological mechanism of insulin signaling

In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling.

25 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Researchers reveal new details about how joint inflammation evolves in rheumatoid arthritis

Walter and Eliza Hall Institute researchers have revealed new details about how joint inflammation evolves in rheumatoid arthritis, and the cells that prolong the inflammatory attack.

25 Feb 2020

Chronic inflammation in pregnancy associated with neurodevelopmental delays in offspring

In pregnant women, obesity, diabetes, hypertension, depression and anxiety can increase the chances of learning delays, behavior problems and mental health issues in their children's early years.

25 Feb 2020

Effects of obesity mirror those of aging, study shows

Globally, an estimated 1.9 billion adults and 380 million children are overweight or obese. According to the World Health Organization, more people are dying from being overweight than underweight. Researchers at Concordia are urging health authorities to rethink their approach to obesity.

25 Feb 2020

Cell News and Research

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Breakthrough research may lead to improved therapeutic options for people with asthma

Stem cell discovery could open the door to new approach for bone marrow transplantation

Study sheds new light on the immune system’s ability to deal with co-infection

Gene-editing is more error-prone than thought, new findings suggest

Aggressive cancers set up a structural framework to keep the immune system at bay

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Targeting overactive immune cells with experimental drug could improve TBI symptoms

Scientists discover new biological mechanism of insulin signaling

Ulcerative colitis and a missing microbe in the gut

Researchers reveal new details about how joint inflammation evolves in rheumatoid arthritis

Chronic inflammation in pregnancy associated with neurodevelopmental delays in offspring

Effects of obesity mirror those of aging, study shows

Researchers succeed in beating-heart surgery to repair mitral valve

Common challenges facing drug development and reimbursement for rare diseases

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

New imaging tool to track cellular events that may initiate obesity-related conditions

Researchers uncover how cancer cells override environmental cues to consume energy

A promising new oral therapy to speed up healing of broken bones

Researchers identify mechanisms underlying immunotherapy-associated tuberculosis

What are the challenges of cell line development? eBook

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Evaluating new approaches for rare disease genomics