Cell News and Research

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Individual response to Ebola predicted by new method

The Ebola virus produces widely varying reactions, from asymptomatic illness to death, in people depending on the individual's susceptibility. But what drives this difference in response? A new study published in the journal Cell Reports on February 2020 goes one step further in understanding how the immune system reacts to the virus causing varying levels of severity of disease between cases.

11 Feb 2020

MGH researchers uncover potential antiviral drug target for treating infectious diseases

As the coronavirus outbreak shows, viruses are a constant threat to humanity. Vaccines are regularly developed and deployed against specific viruses, but that process takes a lot of time, doesn't help everyone who needs protection, and still leaves people exposed to new outbreaks and new viruses.

11 Feb 2020

New technique may yield insights on the immune response to intestinal parasite infections

A new technique may help scientists study the body's immune response to intestinal parasite infections one gut cell at a time, according to a study published today in eLife.

11 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

Using synthetic cell scaffolds to replace animal testing in cancer research

In the field of cancer research, the idea that scientists can disrupt cancer growth by changing the environment in which cancerous cells divide is growing in popularity. The primary way researchers have tested this theory is to conduct experiments using animals.

11 Feb 2020

Fossilized dinosaur tail is home to a 60-million-year-old tumor

The fossilized tail of a young dinosaur that lived on a prairie in southern Alberta, Canada, is home to the remains of a 60-million-year-old tumor.

11 Feb 2020

DNA misfolding linked to heightened risk for Type 1 diabetes

It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome--about six feet of DNA--is compressed into the micrometer space of the nucleus via a three-dimensional folding process.

11 Feb 2020

Major breakthrough in understanding how malaria parasite grows and multiplies

Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has evolved, and how it can be stopped.

11 Feb 2020

NSF CAREER award supports research into biomaterial that promotes osteochondral tissue regeneration

If you're able to walk without pain, give a silent shout-out to your cartilage.

11 Feb 2020

New prophylactic and therapeutic avenues to fight against rabies

Rabies is still responsible for approximately 60,000 human deaths per year mostly in Asia and Africa and affects especially underserved people.

11 Feb 2020

Developing enhanced personalized cancer vaccines

Therapeutic cancer vaccines were first developed 100 years ago and have remained broadly ineffective to date. Before tangible results can be achieved, two major obstacles must be overcome.

11 Feb 2020

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.

11 Feb 2020

Developmental shape-shifting is key to cancer's ability to spread and evade immune defenses

Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don't one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells.

11 Feb 2020

Blue Water Vaccines enters into agreement to develop Streptococcus pneumoniae vaccine with St. Jude

Blue Water Vaccines Inc., a biopharmaceutical company focused on creating transformative vaccines solving global health challenges, has entered into an exclusive worldwide license agreement for the development of a Streptococcus Pneumoniae vaccine with St. Jude Children's Research Hospital, the nation's leading hospital dedicated to understanding, treating and curing childhood cancer and other life-threatening diseases.

11 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

Bats' fierce immune response to viruses could drive zoonotic emergence

It's no coincidence that some of the worst viral disease outbreaks in recent years -- SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus -- originated in bats.

10 Feb 2020

Study explores how some mammals postpone development of their embryos

How do some mammals postpone the development of their embryos to await better conditions for having offspring? A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive enigma, which can occur in more than 130 species of mammals as well as in some marsupials.

10 Feb 2020

New method to treat cancer with iron oxide nanoparticles

The concept is based on the interaction of resonant semiconductor iron oxide Fe2O3 nanoparticles with light. Particles previously loaded with the antitumor drug are injected in vivo and further accumulate at the tumor areas.

10 Feb 2020

New summary report highlights advances and challenges in small cell lung cancer research

In 2017, a group of lung cancer experts posed the question: "Can recent advances in tumor biology that have led to progress treating non-small cell lung cancer translate into improved outcomes for small cell lung cancer?"

10 Feb 2020

Researchers culture human blood-brain barrier on a chip

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's or cancer from getting into the brain.

10 Feb 2020

Cell News and Research

Individual response to Ebola predicted by new method

MGH researchers uncover potential antiviral drug target for treating infectious diseases

New technique may yield insights on the immune response to intestinal parasite infections

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Using synthetic cell scaffolds to replace animal testing in cancer research

Fossilized dinosaur tail is home to a 60-million-year-old tumor

DNA misfolding linked to heightened risk for Type 1 diabetes

Major breakthrough in understanding how malaria parasite grows and multiplies

NSF CAREER award supports research into biomaterial that promotes osteochondral tissue regeneration

New prophylactic and therapeutic avenues to fight against rabies

Developing enhanced personalized cancer vaccines

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

Developmental shape-shifting is key to cancer's ability to spread and evade immune defenses

Blue Water Vaccines enters into agreement to develop Streptococcus pneumoniae vaccine with St. Jude

Finding a cure for canine gliomas may help find treatment for human brain cancer

Bats' fierce immune response to viruses could drive zoonotic emergence

Study explores how some mammals postpone development of their embryos

New method to treat cancer with iron oxide nanoparticles

New summary report highlights advances and challenges in small cell lung cancer research

Researchers culture human blood-brain barrier on a chip

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