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Older age and certain health conditions increase risk of COVID-19 death in boosted individuals

Researchers identify patient groups at a higher risk of death due to COVID-19 among adults who received a second booster dose in England.

12 Jul 2023

Many patients with Lynch syndrome remain undiagnosed, study finds

New research from Cedars-Sinai Cancer investigators could warrant reconsideration of current screening guidelines to include a poorly recognized cause of Lynch syndrome, the most common cause of hereditary colorectal and endometrial cancers.

11 Jul 2023

Mouse model of Hutchinson-Gilford progeria syndrome shows reduction in hepatic H2S levels

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome."

11 Jul 2023

Study reveals how to customize artificial tears to alleviate dry eye symptoms

Compared to artificial tears, or eye drops, human tears are significantly more complex liquids, with a wide range of components including lipids, carbohydrates, proteins, water, and salt.

11 Jul 2023

Orexin is crucial to the regulation of pupil size, research shows

The way the brain regulates pupil size is different from previously thought: fundamentally responsible is the neurotransmitter orexin, as researchers at ETH Zurich have now shown.

11 Jul 2023

New mouse model mimics the development of frailty in older adults

Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals — likely including people — get older.

11 Jul 2023

Is constipation associated with hypertension and cardiovascular events in older Australian adults?

Scientists investigated the association between constipation and cardiovascular events such as angina, myocardial infarction, transient ischemic attack, and stroke, as well as hypertension among a representative population of elderly hospitalized patients in Australia.

11 Jul 2023

Could neutralizing SARS-CoV-2 monoclonal antibodies pre-exposure prophylaxis be cost-effective in a population at risk for severe COVID-19?

A recent study evaluated the cost-effectiveness of monoclonal antibodies as pre-exposure prophylaxis (PrEP) for COVID-19.

11 Jul 2023

mAb-based bELISA developed to detect SARS-CoV-2 antibodies in a broad spectrum of animal species

Researchers developed a mAb-based blocking enzyme-linked immunosorbent assay (bELISA) to detect SARS-CoV-2 in animals.

11 Jul 2023

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

7DW8-5, a glycolipid that utilizes the body's non-specific immune response to quickly combat viral infections, including COVID-19 in vivo.

11 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

How has the prevalence of psychological distress in the adult population of England changed since 2020?

Researchers estimated patterns of psychological distress.

10 Jul 2023

Depression after TBI may not be the same as depression related to other causes, study suggests

A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

10 Jul 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Alarming pediatric hospital admissions linked to COVID-19 in England

Most SARS-CoV-2 associated hospital admissions in children and adolescents in England were due to SARS-CoV-2 or SARS-CoV-2 was a contributory factor. These results should inform future public health initiatives and research.

9 Jul 2023

The vital role of smartphone apps during the COVID-19 pandemic

At the start of the coronavirus disease 2019 (COVID-19) pandemic, analog techniques like nasopharyngeal swab specimens for polymerase chain reaction (PCR) testing were prominent. The widespread use of nonpharmaceutical interventions (NPIs) such as facemasks and social distancing was reminiscent of the influenza outbreak in 1918.

9 Jul 2023

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

In a new study, National Institutes of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to a weaker and less diverse antibody response to viral infections.

7 Jul 2023

Medi-Cal’s fragmented system can make moving a nightmare

When Lloyd Tennison moved from Walnut Creek to Stockton last year, he assumed his coverage under Medi-Cal, California's safety-net health insurance program, would be transferred seamlessly.

7 Jul 2023

Study: Unprocessed red meat and whole grains can be included or left out of a healthy diet

Unprocessed red meat and whole grains can be included or left out of a healthy diet, according to a study conducted in 80 countries across all inhabited continents and published today in European Heart Journal, a journal of the European Society of Cardiology.

6 Jul 2023

Syndrome News and Research

Older age and certain health conditions increase risk of COVID-19 death in boosted individuals

Many patients with Lynch syndrome remain undiagnosed, study finds

Mouse model of Hutchinson-Gilford progeria syndrome shows reduction in hepatic H2S levels

Study reveals how to customize artificial tears to alleviate dry eye symptoms

Orexin is crucial to the regulation of pupil size, research shows

New mouse model mimics the development of frailty in older adults

Is constipation associated with hypertension and cardiovascular events in older Australian adults?

Could neutralizing SARS-CoV-2 monoclonal antibodies pre-exposure prophylaxis be cost-effective in a population at risk for severe COVID-19?

mAb-based bELISA developed to detect SARS-CoV-2 antibodies in a broad spectrum of animal species

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

How has the prevalence of psychological distress in the adult population of England changed since 2020?

Depression after TBI may not be the same as depression related to other causes, study suggests

How B-cells and androgens contribute to the development of PCOS

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Alarming pediatric hospital admissions linked to COVID-19 in England

The vital role of smartphone apps during the COVID-19 pandemic

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

Medi-Cal’s fragmented system can make moving a nightmare

Study: Unprocessed red meat and whole grains can be included or left out of a healthy diet

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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